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Pretreatment thrombocytosis

A prognostic marker for oral squamous cell carcinoma?

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Abstract

Purpose

Thrombocytosis associated with poorer prognoses seems to be a frequent preoperative finding in different kind of cancers. The aim of the present study was to evaluate whether thrombocytosis can be used as a prognostic marker for oral squamous cell carcinoma (SCC).

Methods

Altogether, 288 patients with oral SCC were considered, as well as all platelet counts between 1 and 5 days prior to surgical treatment, recurrence rate, and lymph node metastasis. The minimum follow-up time was 12 months.

Results

The mean preoperative thrombocyte score of the patients who received surgery was 259.55 ± 83.8 Tsd/μl; 273 out of 288 patients were in the normal thrombocyte range, and 12 had a thrombocytosis. From 51 patients with recurrence, three were in the thrombocytosis group, and 45 patients with recurrence were in the normal thrombocyte range.

Conclusion

The present results do not confirm that thrombocytosis can be seen as marker for poor tumor prognosis.

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Conflict of interests

The authors declare that they have no competing interests.

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Authors and Affiliations

  1. Department of Craniomaxillofacial and Oral Surgery, University Hospital Zurich, Frauenklinikstr. 24, 8091, Zurich, Switzerland

    Steffen Kargus, Franz E. Weber, Heinz T. Luebbers, Wolfgang Zemann, Klaus W. Graetz & Astrid L. Kruse

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  1. Steffen Kargus
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  2. Franz E. Weber
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  3. Heinz T. Luebbers
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  4. Wolfgang Zemann
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  5. Klaus W. Graetz
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  6. Astrid L. Kruse
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Corresponding author

Correspondence to Astrid L. Kruse.

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Kargus, S., Weber, F.E., Luebbers, H.T. et al. Pretreatment thrombocytosis. Oral Maxillofac Surg 16, 197–200 (2012). https://doi.org/10.1007/s10006-011-0305-6

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  • DOI: https://doi.org/10.1007/s10006-011-0305-6

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