Skip to main content

Advertisement

SpringerLink
Log in

Management of malignant parotid tumors

  • Original Article
  • Published:
Oral and Maxillofacial Surgery Aims and scope Submit manuscript

Abstract

Introduction

The aims of this study were to review our experience in the treatment of malignant parotid tumors in material from one center over a 12-year period and to assess treatment outcome and particularly survival.

Materials and methods

Thirty-one patients treated primarily by surgery were included in the study. Complete data regarding the demographic details of the patients, tumor stage, presence of regional/distant metastases, treatment, tumor histology, grade, and follow up were compiled. With reference to the extent of tissue removed, partial superficial parotidectomy was performed in 11 patients, superficial parotidectomy, in 14 patients, and total radical parotidectomy, in six patients.

Results

The median time of follow-up was 64 months, ranging from 8 to 144 months. Eight patients developed recurrences. Six patients died within the follow-up time. The overall survival rates at 5 and 10 years were 82.2% and 76.7%, respectively. The 5- and 10-year disease-free survival rates were 74.8% and 69.8%, respectively.

Discussion

For patients with malignant parotid tumors, the treatment should be individualized according to the findings of each specific case, and regarding surgery, particular care and attention should be paid to maintaining all or part of the facial nerve whenever possible.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Armstrong JG, Harrison LB, Spiro RH, Fass DE, Strong EW, Fuks ZY (1990) Malignant tumors of major salivary gland origin. A matched-pair analysis of the role of combined surgery and postoperative radiotherapy. Arch Otolaryngol Head Neck Surg 116:290–293

    Article  PubMed  CAS  Google Scholar 

  2. Armstrong JG, Harrison LB, Thaler HT, Friedlander-Klar H, Fass DE, Zelefsky MJ, Shah JP, Strong EW, Spiro RH (1992) The indications for elective treatment of the neck in cancer of the major salivary glands. Cancer 69:615–619

    Article  PubMed  CAS  Google Scholar 

  3. Ball AB, Fish S, Thomas JM (1995) Malignant epithelial parotid tumours, a rational treatment policy. Br J Surg 82:621–623

    Article  PubMed  CAS  Google Scholar 

  4. Byers RM (1979) The use of postoperative irradiation–its goals and 1978 attainments. Laryngoscope 89:567–572

    Article  PubMed  CAS  Google Scholar 

  5. Calearo C, Pastore A, Storchi OF, Polli G (1998) Parotid gland carcinoma: analysis of prognostic factors. Ann Otol Rhinol Laryngol 107:969–973

    PubMed  CAS  Google Scholar 

  6. Carrillo JF, Vázquez R, Ramírez-Ortega MC, Cano A, Ochoa-Carrillo FJ, Oñate-Ocaña LF (2007) Multivariate prediction of the probability of recurrence in patients with carcinoma of the parotid gland. Cancer 109:2043–2051

    Article  PubMed  Google Scholar 

  7. Frankenthaler RA, Byers RM, Luna MA, Callender DL, Wolf P, Goepfert H (1993) Predicting occult lymph node metastasis in parotid cancer. Arch Otolaryngol Head Neck Surg 119:517–520

    Article  PubMed  CAS  Google Scholar 

  8. Freling NJ, Molenaar WM, Vermey A, Mooyaart EL, Panders AK, Annyas AA, Thijn CJ (1992) Malignant parotid tumors: clinical use of MR imaging and histologic correlation. Radiology 185:691–696

    PubMed  CAS  Google Scholar 

  9. Fu KK, Leibel SA, Levine ML, Friedlander LM, Boles R, Phillips TL (1977) Carcinoma of the major and minor salivary glands: analysis of treatment results and sites and causes of failures. Cancer 40:2882–2890

    Article  PubMed  CAS  Google Scholar 

  10. Harish K (2004) Management of primary malignant epithelial parotid tumors. Surg Oncol 13:7–16

    Article  PubMed  CAS  Google Scholar 

  11. Horn-Ross PL, West DW, Brown SR (1991) Recent trends in the incidence of salivary gland cancer. Int J Epidemiol 20:628–633

    Article  PubMed  CAS  Google Scholar 

  12. Jackson GL, Luna MA, Byers RM (1983) Results of surgery alone and surgery combined with postoperative radiotherapy in the treatment of cancer of the parotid gland. Am J Surg 146:497–500

    Article  PubMed  CAS  Google Scholar 

  13. Johns ME, Goldsmith MM (1989) Current management of salivary gland tumors. Part 2. Oncology (Williston Park) 3:85–91, discussion 94–99

    CAS  Google Scholar 

  14. Kelley DJ, Spiro RH (1996) Management of the neck in parotid carcinoma. Am J Surg 172:695–697

    Article  PubMed  CAS  Google Scholar 

  15. King JJ, Fletcher GH (1971) Malignant tumors of the major salivary glands. Radiology 100:381–384

    PubMed  CAS  Google Scholar 

  16. Klussmann JP, Ponert T, Mueller RP, Dienes HP, Guntinas-Lichius O (2008) Patterns of lymph node spread and its influence on outcome in resectable parotid cancer. Eur J Surg Oncol 34:932–937

    Article  PubMed  CAS  Google Scholar 

  17. Laudadio P, Caliceti U, Cerasoli PT, Rinaldi Ceroni A (1987) Mucoepidermoid tumour of the parotid gland: a very difficult prognostic evaluation. Clin Otolaryngol Allied Sci 12:177–1782

    Article  PubMed  CAS  Google Scholar 

  18. Lim YC, Lee SY, Kim K, Lee JS, Koo BS, Shin HA, Choi EC (2005) Conservative parotidectomy for the treatment of parotid cancers. Oral Oncol 41:1021–1027

    Article  PubMed  Google Scholar 

  19. Lima RA, Tavares MR, Dias FL, Kligerman J, Nascimento MF, Barbosa MM, Cernea CR, Soares JR, Santos IC, Salviano S (2005) Clinical prognostic factors in malignant parotid gland tumors. Otolaryngol Head Neck Surg 133:702–708

    Article  PubMed  Google Scholar 

  20. Luna MA (1999) Pathology of tumors of the salivary glands. In: Thawley SE, Panje WR, Batsakis JG, Lindberg RD (eds) Comprehensive management of head and neck tumors, 2nd edn. WB Saunders, London, pp 1106–1146

    Google Scholar 

  21. O'Brien CJ, Soong SJ, Herrera GA, Urist MM, Maddox WA (1986) Malignant salivary tumors–analysis of prognostic factors and survival. Head Neck Surg 9:82–92

    Article  PubMed  Google Scholar 

  22. Papadogeorgakis N, Skouteris CA, Mylonas AI, Angelopoulos AP (2004) Superficial parotidectomy: technical modifications based on tumour characteristics. J Craniomaxillofac Surg 32:350–353

    Article  PubMed  Google Scholar 

  23. Pedersen D, Overgaard J, Sogaard H, Elbrond O, Overgaard M (1992) Malignant parotid tumors in 110 consecutive patients: treatment results and prognosis. Laryngoscope 102:1064–1069

    Article  PubMed  CAS  Google Scholar 

  24. Sobin LH, Wittekind CH (eds) (1997) UICC TNM classification of malignant tumors, 5th edn. Wiley-Liss, New York

    Google Scholar 

  25. Som PM, Biller HF (1989) High-grade malignancies of the parotid gland: identification with MR imaging. Radiology 173:823–826

    PubMed  CAS  Google Scholar 

  26. Spiro RH (1986) Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 8:177–184

    Article  PubMed  CAS  Google Scholar 

  27. Trappe M, Marsot-Dupuch K, Le Roux C (1991) Study of the salivary glands in 1990. Ann Radiol 34:98–109

    PubMed  CAS  Google Scholar 

  28. Zbären P, Schüpbach J, Nuyens M, Stauffer E (2005) Elective neck dissection versus observation in primary parotid carcinoma. Otolaryngol Head Neck Surg 132:387–391

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, “Evangelismos” General Hospital of Athens, Dental School, University of Athens, Ipsilantou 45-47, Athens, 10676, Greece

    Nikolaos Papadogeorgakis, Lampros Goutzanis, Vassilis Petsinis & Constantinos Alexandridis

  2. Thermopilon 5, Vyron, Athens, 16232, Greece

    Vassilis Petsinis

Authors
  1. Nikolaos Papadogeorgakis
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Lampros Goutzanis
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vassilis Petsinis
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Constantinos Alexandridis
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vassilis Petsinis.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Papadogeorgakis, N., Goutzanis, L., Petsinis, V. et al. Management of malignant parotid tumors. Oral Maxillofac Surg 16, 29–34 (2012). https://doi.org/10.1007/s10006-010-0259-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10006-010-0259-0

Keywords

Search

Navigation