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Hemangioma of the mandible: case report with special emphasis on bone degradation

Oral and Maxillofacial Surgery volume 13, Article number: 239 (2009) Cite this article

Abstract

Purpose

Intraosseous hemangioma of the mandible is a rare tumor. In this report, we present a case with a particularly prominent osteolysis and discuss the histological features of bone degradation.

Materials and methods

We describe a 64-year-old female patient with a cystic tumor mass of the mandible leading to pathologic bone fracture. X-ray analysis was suggestive for aneurysmatic bone cyst. A segment resection was performed.

Results

The histological examination revealed a mesenchymal tumor with numerous capillaries and dilated vessels immunohistochemically being positive for CD31, but not for D2-40. In addition, there was a remarkable increase of osteoclasts that sometimes exhibited Howship’s lacunae. The tumor was diagnosed as intraosseous hemangioma with prominent bone degradation.

Conclusions

Based on our histological findings, it should be further investigated whether there could be an association between angiogenesis and osteoclastogenesis as a central pathway leading to bone destruction in the case of intraosseous hemangiomas.

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Conflict of interest statement

We declare that we have no conflict of interest.

Author information

Affiliations

  1. Institute of Pathology, Johannes Gutenberg University of Mainz, Langenbeckstr. 1, 55101, Mainz, Germany

    Torsten Hansen

  2. Department of Oral and Maxillofacial Surgery, University of Bochum, Bochum, Germany

    Martin Kunkel

  3. Institute of Pathology, Friedrich Schiller University of Jena, Jena, Germany

    Detlef Katenkamp

  4. Department of Oral and Maxillofacial Surgery, Johannes Gutenberg University of Mainz, Mainz, Germany

    Sami Eletr & Wilfried Wagner

Authors
  1. Torsten Hansen
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  2. Martin Kunkel
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  3. Detlef Katenkamp
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  4. Sami Eletr
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  5. Wilfried Wagner
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Corresponding author

Correspondence to Torsten Hansen.

Additional information

T. Hansen and M. Kunkel equally contributed to this case report and share first authorship.

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Hansen, T., Kunkel, M., Katenkamp, D. et al. Hemangioma of the mandible: case report with special emphasis on bone degradation. Oral Maxillofac Surg 13, 239 (2009). https://doi.org/10.1007/s10006-009-0172-6

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  • DOI: https://doi.org/10.1007/s10006-009-0172-6

Keywords

  • Hemangioma
  • Mandible
  • Bone degradation
  • Osteoclast
  • Angiogenesis