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Orale Manifestation einer miliaren Tuberkulose

Oral manifestation of miliary tuberculosis

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Zusammenfassung

Fallbericht

Es wird über den klinischen Verlauf eines 40-jährigen Patienten mit der oralen Manifestation einer miliaren Tuberkuloseinfektion berichtet. Neben Mundschleimhaut und Lunge waren Kolon und Ileum ebenfalls befallen. Diese oralen Schleimhautläsionen können einer malignen Erkrankung ähneln und sind klinisch schwierig zu differenzieren, insbesondere da die Tuberkulose in den industrialisierten Ländern selten geworden ist.

Diskussion

Orale Läsionen und auffallende pulmonale Beschwerden sollten ein Alarmsignal für eine bestehende Tuberkulose sein. Patienten mit derartigen Beschwerden sind einer geeigneten Diagnostik zu unterziehen. Die wichtigsten Diagnostikschritte sind eine Röntgenaufnahme des Thorax und Biopsie aus dem verdächtigen Bereich der Mundhöhle für histologische Untersuchungen. Parallel sollte mit der Koch-Diagnostik, dem Nachweis säurefester Stäbchen in Sputum, Magensaft und Urin, begonnen und Kulturen angelegt werden. Bei negativem Ergebnis kann ggf. im Rahmen einer PCR die DNA von Mycobacterium tuberculosis nachgewiesen werden.

Abstract

Case report

We report on the clinical course of a 40-year-old patient with an oral manifestation of miliary tuberculosis. In addition to oral mucosa and lung, the colon and ileum were also infested. The oral lesions may resemble malignant tumors and are difficult to diagnose, especially because tuberculosis has become a rare disease in industrialized countries.

Discussion

Oral lesions and concomitant pulmonary complaints can be a sign for existing tuberculosis. Patients with these problems should undergo a chest X-ray and a biopsy from the oral mucosa. In addition, tests should be conducted to determine if mycobacteria are present in the sputum, gastric fluid, and urine and cultures grown. In cases with negative results PCR may detect DNA of Mycobacterium tuberculosis.

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Correspondence to M. Krimmel.

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Heigis, G., Krimmel, M., Hoffmann, J. et al. Orale Manifestation einer miliaren Tuberkulose. Mund Kiefer GesichtsChir 9, 180–183 (2005). https://doi.org/10.1007/s10006-005-0596-6

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  • DOI: https://doi.org/10.1007/s10006-005-0596-6

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