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Verkalkender epithelialer odontogener Tumor des Oberkiefers (Pindborg-Tumor)

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Zusammenfassung

Es wird über die Diagnose und Behandlung eines 49-jährigen Patienten mit einem ungewöhnlich großen kalzifizierenden epithelialen odontogenen Tumor („calcifying epithelial odontogenic tumor“, CEOT) des Oberkiefers berichtet. Diese auch unter der Bezeichnung „Pindborg-Tumor“ bekannte Entität zeichnet sich durch ein langsam verdrängendes Wachstum aus. Metastasen sind sehr selten. Radiologisch sind Verkalkungszonen innerhalb des Tumors charakteristisch, jedoch nicht obligat. Die Behandlung bestand aus der lokalen Resektion des Tumors mit Sicherheitsabstand. In zahntragenden Kieferabschnitten ist die Erhaltung der Zähne in der Regel nicht möglich. Über 3 Jahre nach Tumorresektion ist der Patient tumorfrei und prothetisch rehabilitiert. Die Prognose ist günstig. Lokalrezidive sind selten und werden in der Literatur vereinzelt noch Jahrzehnte nach der Erstbehandlung beobachtet. Eine langjährige Verlaufskontrolle ist anzuraten.

Abstract

A male patient presented with an extraordinarily large calcifying epithelial odontogenic tumor (CEOT or Pindborg-tumor) that affected the maxilla. The disease became evident due to alterations in the facial aspect, in particular of the perioral region, caused by the expanding tumor. CEOT is characterised by the slowly growing mass of part of the jaws. Multilocular or extraosseous manifestations are extremely rare. Malignant transformation with metastases is rare. Radiography depicts characteristic, but not obligatory, areas of calcification inside the tumor. The surgical therapy for CEOT is complete local resection with safe margins. If tooth bearing parts of the jaws are affected, these teeth almost always have to be removed. The prognosis is excellent for overall survival. Local recurrences have rarely been reported but may be found even decades after primary treatment. Three years following surgical therapy there is no evidence of local recurrence. A long-term follow-up control is recommended.

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Authors and Affiliations

  1. Klinik und Poliklinik für Zahn-, Mund-, Kiefer- und Gesichtschirurgie (Nordwestdeutsche Kieferklinik), Universität Hamburg

    L. Li &  R. E. Friedrich

  2. Abteilung für Oralpathologie am Institut für Pathologie des Universitätsklinikum Hamburg-Eppendorf, Universität Hamburg

    K. T. Jäkel

  3. Klinik für ZMKG-Chirurgie des Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246 , Hamburg

    R. E. Friedrich

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  1. L. Li
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  2. K. T. Jäkel
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  3. R. E. Friedrich
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Correspondence to R. E. Friedrich.

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Li, L., Jäkel, K.T. & Friedrich, R.E. Verkalkender epithelialer odontogener Tumor des Oberkiefers (Pindborg-Tumor). Mund Kiefer GesichtsChir 8, 46–50 (2004). https://doi.org/10.1007/s10006-003-0517-5

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