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Ciliary ultrastructure in two sisters with Kartagener's syndrome

Medical Molecular Morphology volume 40, pages 34–39 (2007)Cite this article

Abstract

Kartagener's syndrome (KS) is a clinical variant of primary ciliary dyskinesia involving situs inversus associated with chronic airway infections. We studied two sisters; the elder one had dextrocardia and scoliosis, and the younger one had situs inversus of the lung, liver, and stomach as well as dextrocardia. Both patients had chronic sinusitis and chronic bronchitis with bronchiectasis. In both cases, the ciliary defect associated with this syndrome is the absence of inner dynein arms.

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Affiliations

  1. Division of Morphological Science, Biomedical Research Center, Saitama Medical University, 38 Moroyama, Iruma-gun, Saitama, 350-0495, Japan

    Kayoko Tanaka & Masumi Akita

  2. Department of Respiratory Medicine, Saitama Medical University, Saitama, Japan

    Akihisa Sutani & Yuka Uchida

  3. Department of Pathology, Saitama Medical University, Saitama, Japan

    Yoshihiko Shimizu & Michio Shimizu

Authors
  1. Kayoko Tanaka
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  2. Akihisa Sutani
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  3. Yuka Uchida
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  4. Yoshihiko Shimizu
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  5. Michio Shimizu
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  6. Masumi Akita
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Corresponding author

Correspondence to Masumi Akita.

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Tanaka, K., Sutani, A., Uchida, Y. et al. Ciliary ultrastructure in two sisters with Kartagener's syndrome. Med Mol Morphol 40, 34–39 (2007). https://doi.org/10.1007/s00795-007-0354-y

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  • DOI: https://doi.org/10.1007/s00795-007-0354-y

Key words

  • Kartagener's syndrome
  • Primary ciliary dyskinesia
  • Situs inversus
  • Dynein arm
  • Electron microscopy