Abstract
To explore the efficacy and acceptability of a second dose of the 12-session ecological executive skills training (EEST) 1 year after the initial training in children with ADHD. A total of 97 children (aged 6–12) with ADHD who finished the first dose for about 1 year were recruited in the current study. 70 children who agreed to participate the second dose were randomized to the second dose or waitlist group. Both groups were followed up 1 year after the second dose. Executive function, core symptoms were assessed at the time of pre-intervention first dose, pre-intervention second dose, post-intervention second dose and follow-up 1 year after second dose (phase 0–3). For the immediate efficacy, the improvements in the second dose group were greater than the waitlist group on planning by Stockings of Cambridge and delay aversion by Cambridge gambling task (P = 0.02–0.04, η2 = 0.07–0.08). The parent rating of symptoms assessed by ADHD-RS-IV of the second dose group were also greater than the waitlist group rated by self-report. For long term efficacy, Linear mixed model indicated that there was significant time effect for both groups between phase 3 and phase 1, phase 1 and phase 0 on Behavior Rating Scales of Executive Function and ADHD-RS-IV (F = 2.849–21.560, P = 0.001–0.048). The compliance rate was 94.3% for the second dose group and 49% for waitlist group. A second dose of EEST program might bring further efficacy of EF and core symptoms for children with ADHD and it was well accepted.
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Thomas R, Sanders S, Doust J, Beller E, Glasziou P (2015) Prevalence of attention-deficit/hyperactivity disorder: a systematic review and meta-analysis. Pediatrics 135(4):e994–e1001. https://doi.org/10.1542/peds.2014-3482
van Lieshout M, Luman M, Twisk JW, van Ewijk H, Groenman AP, Thissen AJ, Faraone SV, Heslenfeld DJ, Hartman CA, Hoekstra PJ, Franke B, Buitelaar JK, Rommelse NN, Oosterlaan J (2016) A 6-year follow-up of a large European cohort of children with attention-deficit/hyperactivity disorder-combined subtype: outcomes in late adolescence and young adulthood. Eur Child Adolesc Psychiatry 25(9):1007–1017. https://doi.org/10.1007/s00787-016-0820-y
McGough JJ, Biederman J, Wigal SB, Lopez FA, McCracken JT, Spencer T, Zhang Y, Tulloch SJ (2005) Long-term tolerability and effectiveness of once-daily mixed amphetamine salts (Adderall XR) in children with ADHD. J Am Acad Child Adolesc Psychiatry 44(6):530–538. https://doi.org/10.1097/01.chi.0000157550.94702.a2
Serrano-Troncoso E, Guidi M, Alda-Diez JA (2013) Is psychological treatment efficacious for attention deficit hyperactivity disorder (ADHD)? Review of non-pharmacological treatments in children and adolescents with ADHD. Actas espanolas de psiquiatria 41(1):44–51
Cortese S, Ferrin M, Brandeis D, Buitelaar J, Daley D, Dittmann RW, Holtmann M, Santosh P, Stevenson J, Stringaris A, Zuddas A, Sonuga-Barke EJ (2015) Cognitive training for attention-deficit/hyperactivity disorder: meta-analysis of clinical and neuropsychological outcomes from randomized controlled trials. J Am Acad Child Adolesc Psychiatry 54(3):164–174. https://doi.org/10.1016/j.jaac.2014.12.010
Fowler PJ, Henry DB, Schoeny M, Gorman-Smith D, Tolan PH (2014) Effects of the SAFE Children preventive intervention on developmental trajectories of attention-deficit/hyperactivity disorder symptoms. Dev Psychopathol 26(4 Pt 1):1161–1179. https://doi.org/10.1017/S0954579414000170
Pfiffner LJ, Rooney ME, Jiang YY, Haack LM, Beaulieu A, McBurnett K (2018) Sustained effects of collaborative school-home intervention for attention-deficit/hyperactivity disorder symptoms and impairment. J Am Acad Child Adolesc Psychiatry 57(4):245–251. https://doi.org/10.1016/j.jaac.2018.01.016
Lim CG, Lee TS, Guan C, Fung DS, Zhao Y, Teng SS, Zhang H, Krishnan KR (2012) A brain-computer interface based attention training program for treating attention deficit hyperactivity disorder. PLoS One 7(10):e46692. https://doi.org/10.1371/journal.pone.0046692
Craig F, Margari F, Legrottaglie AR, Palumbi R, de Giambattista C, Margari L (2016) A review of executive function deficits in autism spectrum disorder and attention-deficit/hyperactivity disorder. Neuropsychiatr Dis Treatm 12:1191–1202. https://doi.org/10.2147/ndt.S104620
Klingberg T (2010) Training and plasticity of working memory. Trends Cogn Sci 14(7):317–324. https://doi.org/10.1016/j.tics.2010.05.002
Rapport MD, Orban SA, Kofler MJ, Friedman LM (2013) Do programs designed to train working memory, other executive functions, and attention benefit children with ADHD? A meta-analytic review of cognitive, academic, and behavioral outcomes. Clin Psychol Rev 33(8):1237–1252. https://doi.org/10.1016/j.cpr.2013.08.005
Tamm L, Nakonezny PA, Hughes CW (2014) An open trial of a metacognitive executive function training for young children with ADHD. J Atten Disord 18(6):551–559. https://doi.org/10.1177/1087054712445782
Qian Y, Chen M, Shuai L, Cao QJ, Yang L, Wang YF (2017) Effect of an ecological executive skill training program for school-aged children with attention deficit hyperactivity disorder: a randomized controlled clinical trial. Chin Med J (Engl) 130(13):1513–1520. https://doi.org/10.4103/0366-6999.208236
Shuai L, Daley D, Wang YF, Zhang JS, Kong YT, Tan X, Ji N (2017) Executive function training for children with attention deficit hyperactivity disorder. Chin Med J (Engl) 130(5):549–558. https://doi.org/10.4103/0366-6999.200541
Diamond A, Ling DS (2016) Conclusions about interventions, programs, and approaches for improving executive functions that appear justified and those that, despite much hype, do not. Dev Cogn Neurosci 18:34–48. https://doi.org/10.1016/j.dcn.2015.11.005
Boyer BE, Geurts HM, Prins PJ, Van der Oord S (2016) One-year follow-up of two novel CBTs for adolescents with ADHD. Eur Child Adolesc Psychiatry 25(3):333–337. https://doi.org/10.1007/s00787-015-0776-3
Taylor SJ, Barker LA, Heavey L, McHale S (2015) The longitudinal development of social and executive functions in late adolescence and early adulthood. Front Behav Neurosci 9:252. https://doi.org/10.3389/fnbeh.2015.00252
Barkley RA (1997) Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD. Psychol Bull 121(1):65–94. https://doi.org/10.1037/0033-2909.121.1.65
Gau SS, Shang CY (2010) Executive functions as endophenotypes in ADHD: evidence from the Cambridge Neuropsychological Test Battery (CANTAB). J Child Psychol Psychiatry 51(7):838–849. https://doi.org/10.1111/j.1469-7610.2010.02215.x
DeVito EE, Blackwell AD, Fau-Kent L, Ersche KD, Clark L, Salmond CH, Dezsery AM, Sahakian BJ (2008) The effects of methylphenidate on decision making in attention-deficit/hyperactivity disorder. Biol Psychiatry 64(7):636–639. https://doi.org/10.1016/j.biopsych.2008.04.017
Coghill DR, Banaschewski T, Bliss C, Robertson B, Zuddas A (2018) Cognitive function of children and adolescents with attention-deficit/hyperactivity disorder in a 2-year open-label study of lisdexamfetamine dimesylate. CNS Drugs 32(1):85–95. https://doi.org/10.1007/s40263-017-0487-z
Gioia GA, Isquith PK, Kenworthy L, Barton RM (2002) Profiles of everyday executive function in acquired and developmental disorders. Child Neuropsychol 8(2):121–137. https://doi.org/10.1076/chin.8.2.121.8727
Qian Y, Wang YF (2007) Reliability and validity of behavior rating scale of executive function parent form for school age children in China. Beijing Da Xue Xue Bao Yi Xue Ban 39(3):277–283
Su LY, Geng YG, Wang H, Du YS, Zhao LS, Fan F (2006) Norm of ADHD diagnostic scale-parent version in chinese urban children. Chin J Pract Pediatr 11:833–836. https://doi.org/10.3969/j.issn.1005-2224.2006.11.013
Qian Y, Du QX, Qu S, Wang YF (2011) Reliability and validity of the Chinese version of Weiss functional impairment scale-parent form for school age children. Chin Mental Health J 25(10):767–771. https://doi.org/10.1007/s12264-011-1035-3
Sonuga-Barke EJS (2003) The dual pathway model of AD/HD: an elaboration of neuro-developmental characteristics. Neurosci Biobehav Rev 27(7):593–604. https://doi.org/10.1016/j.neubiorev.2003.08.005
Dittner AJ, Hodsoll J, Rimes KA, Russell AJ, Chalder T (2018) Cognitive-behavioural therapy for adult attention-deficit hyperactivity disorder: a proof of concept randomised controlled trial. Acta Psychiatr Scand 137(2):125–137. https://doi.org/10.1111/acps.12836
Titz C, Karbach J (2014) Working memory and executive functions: effects of training on academic achievement. Psychol Res 78(6):852–868. https://doi.org/10.1007/s00426-013-0537-1
Bennett SJ, Holmes J, Buckley S (2013) Computerized memory training leads to sustained improvement in visuospatial short-term memory skills in children with down syndrome. Am J Intellect Dev Disabil 118(3):179–192. https://doi.org/10.1352/1944-7558-118.3.179
Qian Y, Shuai L, Chan RC, Qian QJ, Wang Y (2013) The developmental trajectories of executive function of children and adolescents with attention deficit hyperactivity disorder. Res Dev Disabil 34(5):1434–1445. https://doi.org/10.1016/j.ridd.2013.01.033
Evans SW, Owens JS, Bunford N (2014) Evidence-based psychosocial treatments for children and adolescents with attention-deficit/hyperactivity disorder. J Clin Child Adolesc Psychol 43(4):527–551. https://doi.org/10.1080/15374416.2013.850700
Horigian VE, Anderson AR, Szapocznik J (2016) Family-based treatments for adolescent substance use. Child Adolesc Psychiatr Clin N Am 25(4):603–628. https://doi.org/10.1016/j.chc.2016.06.001
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This work was supported by Beijing Municipal Science & Technology Commission (Grant number Z191100006619047), the Major State Basic Research Development Program of China (973 Program, 2014CB846100), and Capital Health Development Research Fund (2011-4024-04).
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Qian, Y., Fan, Z., Gao, B. et al. Efficacy and acceptability of a second dose of ecological executive skills training for children with ADHD: a randomized controlled study and follow-up. Eur Child Adolesc Psychiatry 30, 921–935 (2021). https://doi.org/10.1007/s00787-020-01571-y
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DOI: https://doi.org/10.1007/s00787-020-01571-y