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European Child & Adolescent Psychiatry

, Volume 28, Issue 11, pp 1499–1506 | Cite as

Maternal pre-pregnancy weight status and health care use for mental health conditions in the offspring

  • Alexa Grudzinski
  • Leslie Anne Campbell
  • Lihui Liu
  • Mary Margaret Brown
  • Linda Dodds
  • Stefan KuhleEmail author
Original Contribution
  • 218 Downloads

Abstract

The objective of this study was to examine the relationship between pre-pregnancy maternal weight status and offspring physician visits for mental health conditions in childhood and adolescence. We conducted a population-based retrospective cohort study of singleton infants born between the years of 1989 and 1993 using a linkage of the Nova Scotia Atlee Perinatal Database with administrative health data. Offspring were followed from birth to age 18 years. Maternal weight status was categorized according to WHO body mass index cutoffs. The number of physician visits for any mental health condition, mood, anxiety, and adjustment disorders, conduct disorder, and attention-deficit hyperactivity disorder (ADHD) from age 0–18 years was determined from ICD codes in physician billings and hospital discharge abstract data. Negative binomial regression adjusting for sociodemographics, maternal psychiatric disorders and smoking was used to model the association. In total, 38,211 mother–offspring pairs were included in the cohort. Within the first 18 years of life, offspring of mothers with obesity had significantly more physician visits for any mental health condition [adjusted incidence rate ratio (IRR) 1.26, 95% CI 1.19–1.34], mood, anxiety, and adjustment disorders (IRR 1.16, 95% CI 1.07–1.25), conduct disorder (IRR 1.25, 95% CI 1.08–1.45), and ADHD (IRR 1.45, 95% CI 1.24–1.69) compared to mothers of normal weight. Associations for mood, anxiety, and adjustment disorders and conduct disorder were strongest at 13–18 years. Offspring of mothers with obesity appear to use health care for mental health conditions more frequently than offspring of normal weight mothers.

Keywords

Pregnancy Obesity Child Adolescent Mental disorders 

Notes

Acknowledgements

This work was supported by a Canadian Institutes of Health Research operating grant awarded to Dr. Stefan Kuhle (FRN #134531). Alexa Grudzinski held an Andrew Putnam Summer Research Studentship from the Faculty of Medicine, Dalhousie University. Leslie Anne Campbell holds a Sobey Family Chair in Child & Adolescent Mental Health Outcomes. Mary Margaret Brown received a Nova Scotia Research and Innovation Graduate Scholarship from the Government of Nova Scotia and a Scotia Scholar Doctoral Award from the Nova Scotia Health Research Foundation. Portions of the data used in this report were made available by Health Data Nova Scotia of Dalhousie University. Although this research is based on data obtained from the Nova Scotia Department of Health and Wellness, the observations and opinions expressed are those of the authors and do not represent those of either Health Data Nova Scotia or the Department of Health and Wellness.

Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Supplementary material

787_2019_1312_MOESM1_ESM.docx (21 kb)
Supplementary material 1 (DOCX 20 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Faculty of MedicineDalhousie UniversityHalifaxCanada
  2. 2.Department of Community Health and EpidemiologyDalhousie UniversityHalifaxCanada
  3. 3.Departments of Obstetrics and Gynaecology and Pediatrics, Perinatal Epidemiology Research UnitDalhousie UniversityHalifaxCanada
  4. 4.Perinatal Epidemiology Research UnitIWK Health CentreHalifaxCanada

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