Emotional valence detection in adolescents with oppositional defiant disorder/conduct disorder or autism spectrum disorder

Abstract

Oppositional defiant disorder, conduct disorder (ODD/CD), and autism spectrum disorder (ASD) share poor empathic functioning and have been associated with impaired emotional processing. However, no previous studies directly compared similarities and differences in these processes for the two disorders. A two-choice emotional valence detection task requiring differentiation between positive, negative, and neutral IAPS pictures was administered to 52 adolescents (12–19 years) with ODD/CD, 52 with ASD and 24 typically developing individuals (TDI). Callous–unemotional (CU) traits were assessed by self- and parent reports using the Inventory of callous–unemotional traits. Main findings were that adolescents with ODD/CD or ASD both performed poorer than TDI in terms of accuracy, yet only the TDI—not both clinical groups—had relatively most difficulty in discriminating between positive versus neutral pictures compared to neutral–negative or positive–negative contrasts. Poorer performance was related to a higher level of CU traits. The results of the current study suggest youth with ODD/CD or ASD have a diminished ability to detect emotional valence which is not limited to facial expressions and is related to a higher level of CU traits. More specifically, youth with ODD/CD or ASD seem to have a reduced processing of positive stimuli and/or lack a ‘positive perception bias’ present in TDI that could either contribute to the symptoms and/or be a result of having the disorder and may contribute to the comorbidity of both disorders.

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References

  1. 1.

    Bari A, Robbins TW (2013) Inhibition and impulsivity: behavioral and neural basis of response control. Prog Neurobiol 108:44–79

    Article  Google Scholar 

  2. 2.

    Gray JA (1970) The psychophysiological basis of introversion-extraversion. Behav Res Ther 8:249–266

    Article  CAS  PubMed  Google Scholar 

  3. 3.

    Fowles DC (1980) The three arousal model: implications of gray’s two-factor learning theory for heart rate, electrodermal activity, and psychopathy. Psychophysiology 17:87–104

    Article  CAS  PubMed  Google Scholar 

  4. 4.

    Todorov A (2008) Evaluating faces on trustworthiness: an extension of systems for recognition of emotions signaling approach/avoidance behaviors. Ann N Y Acad Sci 1124:208–224

    Article  PubMed  Google Scholar 

  5. 5.

    Blair RJR (1995) A cognitive developmental approach to morality: investigating the psychopath. Cognition 57:1–29

    Article  CAS  PubMed  Google Scholar 

  6. 6.

    Boyer P, Bergstrom B (2011) Threat-detection in child development: an evolutionary perspective. Neurosci Biobehav Rev 35:1034–1041

    Article  PubMed  Google Scholar 

  7. 7.

    Hägele C, Friedel E, Schlagenhauf F, Sterzer P, Beck A, Bermpohl F, Stoy M, Held-Poschardt D, Wittmann A, Strohle A, Heinz A (2016) Affective responses across psychiatric disorders—a dimensional approach. Neurosci Lett 623:71–78

    Article  CAS  PubMed  Google Scholar 

  8. 8.

    Jayaro C, de la Vega I, Diaz-Marsa M, Montes A, Carrasco JL (2008) The use of the international affective picture system for the study of affective dysregulation in mental disorders. Actas Esp Psiquiatr 36:177–182

    CAS  PubMed  Google Scholar 

  9. 9.

    Fakhoury M (2015) Autistic spectrum disorders: a review of clinical features, theories and diagnosis. Int J Dev Neurosci 43:70–77

    Article  PubMed  Google Scholar 

  10. 10.

    Matthys W, van Goozen SH, de Vries H, Cohen-Kettenis PT, van Engeland H (1998) The dominance of behavioural activation over behavioural inhibition in conduct disordered boys with or without attention deficit hyperactivity disorder. J Child Psychol Psychiatry 39:643–651

    Article  CAS  PubMed  Google Scholar 

  11. 11.

    Hirsh JB, Kang SK (2016) Mechanisms of identity conflict: uncertainty, anxiety, and the behavioral inhibition system. Pers Soc Psychol Rev 20:223–244

    Article  PubMed  Google Scholar 

  12. 12.

    Alloy LB, Abramson LY, Walshaw PD, Cogswell A, Grandin LD, Hughes ME, Iacoviello BM, Whitehouse WG, Urosevic S, Nusslock R, Hogan ME (2008) Behavioral approach system and behavioral inhibition system sensitivities and bipolar spectrum disorders: prospective prediction of bipolar mood episodes. Bipolar Disord 10:310–322

    Article  PubMed  Google Scholar 

  13. 13.

    Sharp C, Petersen N, Goodyer I (2008) Emotional reactivity and the emergence of conduct problems and emotional symptoms in 7- to 11-year-olds: a 1-year follow-up study. J Am Acad Child Adolesc Psychiatry 47:565–573

    Article  PubMed  Google Scholar 

  14. 14.

    Wahlund K, Sorman K, Gavazzeni J, Fischer H, Kristiansson M (2010) Attenuated subjective ratings and skin conductance responses to neutral and negative pictures in non-psychopathic mentally disordered offenders with various diagnoses. Psychiatry Res 180:30–34

    Article  PubMed  Google Scholar 

  15. 15.

    Mathersul D, McDonald S, Rushby JA (2013) Automatic facial responses to affective stimuli in high-functioning adults with autism spectrum disorder. Physiol Behav 109:14–22

    Article  CAS  PubMed  Google Scholar 

  16. 16.

    Kaat AJ, Lecavalier L (2013) Disruptive behavior disorders in children and adolescents with autism spectrum disorders: a review of the prevalence, presentation, and treatment. Res Autism Spectr Disord 7:1579–1594

    Article  Google Scholar 

  17. 17.

    Hart-Kerkhoffs’t LA, Jansen LM, Doreleijers TA, Vermeiren R, Minderaa RB, Hartman CA (2009) Autism spectrum disorder symptoms in juvenile suspects of sex offenses. J Clin Psychiatry 70:266–272

    Article  Google Scholar 

  18. 18.

    Geluk CA, Jansen LM, Vermeiren R, Doreleijers TA, van Domburgh L, de Bildt A, Twisk JW, Hartman CA (2012) Autistic symptoms in childhood arrestees: longitudinal association with delinquent behavior. J Child Psychol Psychiatry 53:160–167

    Article  PubMed  Google Scholar 

  19. 19.

    Hartman CA, Geurts HM, Franke B, Buitelaar JK, Rommelse NNJ (2016) Changing ASD-ADHD symptom co-occurrence across the lifespan with adolescence as crucial time window: Illustrating the need to go beyond childhood. Neurosci Biobehav Rev 71:529–541

    Article  PubMed  PubMed Central  Google Scholar 

  20. 20.

    Van Steensel FJ, Bogels SM, de Bruin EI (2013) Psychiatric comorbidity in children with autism spectrum disorders: a comparison with children with ADHD. J Child Fam Stud 22:368–376

    Article  PubMed  Google Scholar 

  21. 21.

    Blanco C, Wall MM, He JP, Krueger RF, Olfson M, Jin CJ, Burstein M, Merikangas KR (2015) The space of common psychiatric disorders in adolescents: comorbidity structure and individual latent liabilities. J Am Acad Child Adolesc Psychiatry 54:45–52

    Article  PubMed  Google Scholar 

  22. 22.

    Caspi A, Houts RM, Belsky DW, Goldman-Mellor SJ, Harrington H, Israel S, Meier MH, Ramrakha S, Shalev I, Poulton R, Moffitt TE (2014) The p factor: one general psychopathology factor in the structure of psychiatric disorders? Clin Psychol Sci 2:119–137

    Article  PubMed  PubMed Central  Google Scholar 

  23. 23.

    Cuthbert BN, Insel TR (2013) Toward the future of psychiatric diagnosis: the seven pillars of RDoC. BMC Med 11:126

    Article  PubMed  PubMed Central  Google Scholar 

  24. 24.

    Lamm C, Bukowski H, Silani G (2016) From shared to distinct self-other representations in empathy: evidence from neurotypical function and socio-cognitive disorders. Philos Trans R Soc Lond B Biol Sci 371:20150083

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. 25.

    Decety J, Moriguchi Y (2007) The empathic brain and its dysfunction in psychiatric populations: implications for intervention across different clinical conditions. BiopsychosocMed 1:22

    Article  Google Scholar 

  26. 26.

    Blair RJR (2005) Responding to the emotions of others: dissociating forms of empathy through the study of typical and psychiatric populations. Conscious Cogn 14:698–718

    Article  CAS  PubMed  Google Scholar 

  27. 27.

    Bons D, Van den Broek E, Scheepers F, Herpers P, Rommelse N, Buitelaar JK (2013) Motor, emotional, and cognitive empathy in children and adolescents with autism spectrum disorder and conduct disorder. J Abnorm Child Psychol 41:425–443

    Article  PubMed  Google Scholar 

  28. 28.

    Baron-Cohen S, Leslie AM, Frith U (1985) Does the autistic child have a “theory of mind”? Cognition 21:37–46

    Article  CAS  Google Scholar 

  29. 29.

    Happé F, Frith U (2014) Annual research review: towards a developmental neuroscience of atypical social cognition. J Child Psychol Psychiatry 55:553–557

    Article  PubMed  Google Scholar 

  30. 30.

    Frick PJ, O’Brien BS, Wootton JM, McBurnett K (1994) Psychopathy and conduct problems in children. J Abnorm Psychol 103:700–707

    Article  CAS  PubMed  Google Scholar 

  31. 31.

    Jones AP, Happé FG, Gilbert F, Burnett S, Viding E (2010) Feeling, caring, knowing: different types of empathy deficit in boys with psychopathic tendencies and autism spectrum disorder. J Child Psychol Psychiatry 51:1188–1197

    Article  PubMed  PubMed Central  Google Scholar 

  32. 32.

    Schwenck C, Mergenthaler J, Keller K, Zech J, Salehi S, Taurines R, Romanos M, Schecklmann M, Schneider W, Warnke A, Freitag CM (2012) Empathy in children with autism and conduct disorder: group-specific profiles and developmental aspects. J Child Psychol Psychiatry 53:651–659

    Article  PubMed  Google Scholar 

  33. 33.

    Herpers PC, Klip H, Rommelse NN, Greven CU, Buitelaar JK (2016) Associations between high callous-unemotional traits and quality of life across youths with non-conduct disorder diagnoses. Eur Child Adolesc Psychiatry 25:547–555

    Article  PubMed  Google Scholar 

  34. 34.

    Leno VC, Charman T, Pickles A, Jones CR, Baird G, Happé F, Simonoff E (2015) Callous-unemotional traits in adolescents with autism spectrum disorder. Br J Psychiatry 207:392–399

    Article  PubMed Central  Google Scholar 

  35. 35.

    Biederman J, Faraone SV, Milberger S, Jetton JG, Chen L, Mick E, Greene RW, Russell RL (1996) Is childhood oppositional defiant disorder a precursor to adolescent conduct disorder? Findings from a four-year follow-up study of children with ADHD. J Am Acad Child Adolesc Psychiatry 35:1193–1204

    Article  CAS  PubMed  Google Scholar 

  36. 36.

    Burke JD, Hipwell AE, Loeber R (2010) Dimensions of oppositional defiant disorder as predictors of depression and conduct disorder in preadolescent girls. J Am Acad Child Adolesc Psychiatry 49:484–492

    PubMed  PubMed Central  Google Scholar 

  37. 37.

    Association AP (2000) Diagnostic and statistical manual of mental disorders. American Psychiatric Association, Washington

    Google Scholar 

  38. 38.

    Leckman JF, Sholomkas D, Thompson WD, Belanger A, Weissman MM (1982) Best estimate of a lifetime psychiatric diagnosis: a methodological study. Arch Gen Psychiatry 39:879–883

    Article  CAS  PubMed  Google Scholar 

  39. 39.

    Steenhuis MP, Serra M, Minderaa RB, Hartman CA (2009) An internet version of the diagnostic interview schedule for children (DISC-IV): correspondence of the ADHD section with the paper-and-pencil version. Psychol Assess 21:231–234

    Article  PubMed  Google Scholar 

  40. 40.

    Shaffer D, Fisher P, Lucas CP, Dulcan MK, Schwab-Stone ME (2000) NIMH diagnostic interview schedule for children version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J Am Acad Child Adolesc Psychiatry 39:28–38

    Article  CAS  PubMed  Google Scholar 

  41. 41.

    Wechsler D (1991) Manual for the Wechsler Intelligence Scale for Children—third edition (WISC-III). The Psychological Corporation, San Antonio

    Google Scholar 

  42. 42.

    Groth-Marnat G (1997) Handbook of psychological assessment. Wiley, New York

    Google Scholar 

  43. 43.

    Wechsler D (1997) Wechsler Adult Intelligence Scale—third edition (WAIS-III). Administration and scoring manual. The Psychological Corporation, San Antonio

    Google Scholar 

  44. 44.

    Brand N, Von Borries K, Bulten E (2010) Progress with MINDS, a testmanager for psychological assessment, research and education: applications in the forensic psychiatric domain. In: Spink AJ, Grieco F, Krips OE, Loyens LWS, Noldus PJJ, Zimmerman PH (eds) Proceedings of Measuring Behavior 2010. Eindhoven, p 396–398

  45. 45.

    Lang PJ, Bradley MM, Cuthbert BN (1997) International affective picture system (IAPS). NIMH Center for Emotion and Attention, Washington

    Google Scholar 

  46. 46.

    Brand N, Groot P (2007) Test manager mental information processing and neuropsychological diagnostic system (MINDS). In: Klinische and Gezondheids Psychologie van de Faculteit Sociale Wetenschappen, Universiteit Utrecht., Utrecht

  47. 47.

    Roose A, Bijttebier P, Decoene S, Claes L, Frick PJ (2010) Assessing the affective features of psychopathy in adolescence: a further validation of the inventory of callous and unemotional traits. Assessment 17:44–57

    Article  PubMed  Google Scholar 

  48. 48.

    Decuyper M, De Clercq B, De Bolle M, De Fruyt F (2009) Validation of FFM PD counts for screening personality pathology and psychopathy in adolescence. J Pers Disord 23:587–605

    Article  PubMed  Google Scholar 

  49. 49.

    Kimonis ER, Frick PJ, Skeem JL, Marsee MA, Cruise K, Munoz LC, Aucoin KJ, Morris AS (2008) Assessing callous-unemotional traits in adolescent offenders: validation of the inventory of callous-unemotional traits. Int J Law Psychiatry 31:241–252

    Article  PubMed  Google Scholar 

  50. 50.

    Rutter M, Bailey A, Lord C (2003) Social communication questionnaire (SCQ). Western Psychological Services, Torrance

    Google Scholar 

  51. 51.

    Berument SK, Rutter M, Lord C, Pickles A, Bailey A (1999) Autism screening questionnaire: diagnostic validity. Br J Psychiatry 175:444–451

    Article  CAS  PubMed  Google Scholar 

  52. 52.

    Chandler S, Charman T, Baird G, Simonoff E, Loucas T, Meldrum D, Scott M, Pickles A (2007) Validation of the social communication questionnaire in a population cohort of children with autism spectrum disorders. J Am Acad Child Adolesc Psychiatry 46:1324–1332

    Article  PubMed  Google Scholar 

  53. 53.

    Charman T, Baird G, Simonoff E, Loucas T, Chandler S, Meldrum D, Pickles A (2007) Efficacy of three screening instruments in the identification of autistic-spectrum disorders. Br J Psychiatry 191:554–559

    Article  PubMed  Google Scholar 

  54. 54.

    Shepperd JA, Pogge G, Howell JL (2017) Assessing the consequences of unrealistic optimism: challenges and recommendations. Conscious Cogn 50:69–78

    Article  PubMed  Google Scholar 

  55. 55.

    Taylor KM, Shepperd JA (1998) Bracing for the worst: severity, testing, and feedback timing as moderators of the optimistic bias. Pers Soc Psychol Bull 24:915–926

    Article  Google Scholar 

  56. 56.

    Vaish A, Grossmann T, Woodward A (2008) Not all emotions are created equal: the negativity bias in social-emotional development. Psychol Bull 134:383–403

    Article  PubMed  PubMed Central  Google Scholar 

  57. 57.

    Herpers PC, Scheepers FE, Bons DM, Buitelaar JK, Rommelse NN (2014) The cognitive and neural correlates of psychopathy and especially callous-unemotional traits in youths: a systematic review of the evidence. Dev Psychopathol 26:245–273

    Article  PubMed  Google Scholar 

  58. 58.

    Oberman LM, Winkielman P, Ramachandran VS (2009) Slow echo: facial EMG evidence for the delay of spontaneous, but not voluntary, emotional mimicry in children with autism spectrum disorders. Dev Sci 12:510–520

    Article  PubMed  Google Scholar 

  59. 59.

    Van Honk J, Schutter DJ (2006) Unmasking feigned sanity: a neurobiological model of emotion processing in primary psychopathy. Cogn Neuropsychiatry 11:285–306

    Article  PubMed  Google Scholar 

  60. 60.

    De Wied M, van Boxtel A, Matthys W, Meeus W (2012) Verbal, facial and autonomic responses to empathy-eliciting film clips by disruptive male adolescents with high versus low callous-unemotional traits. J Abnorm Child Psychol 40:211–223

    Article  PubMed  Google Scholar 

  61. 61.

    Masi G, Milone A, Pisano S, Lenzi F, Muratori P, Gemo I, Bianchi L, Mazzone L, Postorino V, Sanges V, Williams R, Vicari S (2014) Emotional reactivity in referred youth with disruptive behavior disorders: the role of the callous-unemotional traits. Psychiatry Res 220:426–432

    Article  PubMed  Google Scholar 

  62. 62.

    Michonski JD, Sharp C (2010) Revisiting Lynam’s notion of the “fledgling psychopath”: are HIA-CP children truly psychopathic-like? Child Adolesc Psychiatry Ment Health 4:24

    Article  PubMed  PubMed Central  Google Scholar 

  63. 63.

    Sharp C, van Goozen S, Goodyer I (2006) Children’s subjective emotional reactivity to affective pictures: gender differences and their antisocial correlates in an unselected sample of 7-11-year-olds. J Child Psychol Psychiatry 47:143–150

    Article  PubMed  Google Scholar 

  64. 64.

    Hodsoll S, Lavie N, Viding E (2014) Emotional attentional capture in children with conduct problems: the role of callous-unemotional traits. Front Hum Neurosci 8:570

    Article  PubMed  PubMed Central  Google Scholar 

  65. 65.

    Kimonis ER, Fanti KA, Anastassiou-Hadjicharalambous X, Mertan B, Goulter N, Katsimicha E (2016) Can callous-unemotional traits be reliably measured in preschoolers? J Abnorm Child Psychol 44:625–638

    Article  PubMed  Google Scholar 

  66. 66.

    Kimonis ER, Frick PJ, Cauffman E, Goldweber A, Skeem J (2012) Primary and secondary variants of juvenile psychopathy differ in emotional processing. Dev Psychopathol 24:1091–1103

    Article  PubMed  Google Scholar 

  67. 67.

    Dackis MN, Rogosch FA, Cicchetti D (2015) Child maltreatment, callous-unemotional traits, and defensive responding in high-risk children: an investigation of emotion-modulated startle response. Dev Psychopathol 27:1527–1545

    Article  PubMed  PubMed Central  Google Scholar 

  68. 68.

    Ezpeleta L, Navarro JB, de la Osa N, Penelo E, Trepat E, Martin V, Domenech JM (2017) Attention to emotion through a go/no-go task in children with oppositionality and callous-unemotional traits. Compr Psychiatry 75:35–45

    Article  PubMed  Google Scholar 

  69. 69.

    Chmielewski WX, Beste C (2015) Action control processes in autism spectrum disorder–insights from a neurobiological and neuroanatomical perspective. Prog Neurobiol 124:49–83

    Article  PubMed  Google Scholar 

  70. 70.

    Gaigg SB (2012) The interplay between emotion and cognition in autism spectrum disorder: implications for developmental theory. Front Integr Neurosci 6:113

    Article  PubMed  PubMed Central  Google Scholar 

  71. 71.

    Nuske HJ, Vivanti G, Dissanayake C (2013) Are emotion impairments unique to, universal, or specific in autism spectrum disorder? A comprehensive review. Cogn Emot 27:1042–1061

    Article  PubMed  Google Scholar 

  72. 72.

    Matthys W, Vanderschuren LJ, Schutter DJ, Lochman JE (2012) Impaired neurocognitive functions affect social learning processes in oppositional defiant disorder and conduct disorder: implications for interventions. Clin Child Fam Psychol Rev 15:234–246

    Article  PubMed  Google Scholar 

  73. 73.

    Connor DF, Steeber J, McBurnett K (2010) A review of attention-deficit/hyperactivity disorder complicated by symptoms of oppositional defiant disorder or conduct disorder. J Dev Behav Pediatr 31:427–440

    Article  PubMed  Google Scholar 

  74. 74.

    Waschbusch DA (2002) A meta-analytic examination of comorbid hyperactive-impulsive-attention problems and conduct problems. Psychol Bull 128:118–150

    Article  PubMed  Google Scholar 

  75. 75.

    Willcutt EG, Doyle AE, Nigg JT, Faraone SV, Pennington BF (2005) Validity of the executive function theory of attention-deficit/hyperactivity disorder: a meta-analytic review. Biol Psychiatry 57:1336–1346

    Article  PubMed  Google Scholar 

  76. 76.

    Pishyareh E, Tehrani-Doost M, Mahmoodi-Gharaie J, Khorrami A, Rahmdar SR (2015) A comparative study of sustained attentional bias on emotional processing in ADHD children to pictures with eye-tracking. Iran J Child Neurol 9:64–70

    PubMed  PubMed Central  Google Scholar 

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Acknowledgements

This study was supported by Karakter Child and Adolescent Psychiatry, University Center. The study is further supported by the European Union 7th Framework programs AGGRESSOTYPE (602805) and MATRICS (603016) and by an NWO Brain and Cognition Grant (056-24-011). We are grateful to participating families.

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Correspondence to Pierre C. M. Herpers.

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Conflict of interest

In the past 3 years, Dr. Buitelaar has been a consultant to/member of advisory board of/and/or speaker for Janssen Cilag BV, Eli Lilly, Bristol-Myer Squibb, Shering Plough, UCB, Shire, Novartis, and Servier. He is not an employee of any of these companies, and not a stock shareholder of any of these companies. He has no other financial or material support, including expert testimony, patents, and royalties. Drs. Herpers, Bakker, Greven, Wiegers, Nijhof, Baanders, and Rommelse declare that they have no conflict of interest.

Ethical approval

This study was approved by the Dutch Central Committee on Research involving Human Subjects, protocol number NL26773.000.09 (Centrale Commissie Mensgebonden Onderzoek; CCMO). As such, all procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants, and their parents, included in the study.

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Herpers, P.C.M., Bakker-Huvenaars, M.J., Greven, C.U. et al. Emotional valence detection in adolescents with oppositional defiant disorder/conduct disorder or autism spectrum disorder. Eur Child Adolesc Psychiatry 28, 1011–1022 (2019). https://doi.org/10.1007/s00787-019-01282-z

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Keywords

  • Emotional valence detection task
  • Conduct disorder
  • Oppositional defiant disorder
  • Autism spectrum disorder
  • Callous–unemotional traits