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Autonomic arousal in anxious and typically developing youth during a stressor involving error feedback

European Child & Adolescent Psychiatry volume 26, pages 1423–1432 (2017)Cite this article

Abstract

Anxiety has been proposed to influence psychophysiological reactivity in children and adolescents. However, the extant empirical literature has not always found physiological reactivity to be associated with anxiety in youth. Further, most investigations have not examined psychophysiological reactivity in real time over the course of acute stress. To test the impact of anxiety disorder status on autonomic arousal in youth, we compared youth with primary anxiety disorders (N = 24) to typically developing (TD) youth (N = 22) on heart rate (HR), heart rate variability (HRV), and respiratory sinus arrhythmia (RSA) during an acute stressor in which youth received error-related feedback. We also conducted exploratory analyses on youth performance during the task. Youth ages 9–17 participated in the arithmetic portion of the Trier Social Stress Test for Children (Buske-Kirschbaum et al., Psychosom 59:419–426, 1997), during which time they received consecutive, standardized feedback that they made calculation errors. Results indicated that, compared to their TD counterparts, the anxious group demonstrated elevated HR and suppressed HRV during initial provision of error feedback and during the recovery period. No group differences were found for RSA. Additionally, overall TD youth made a greater proportion of errors than anxious youth. Clinically, these findings may provide preliminary support for anxious youth exhibiting physiological reactivity in response to receipt of error-related feedback, and may have implications for understanding biological processes during stress. This work underscores the need for further study of when and how anxiety may influence autonomic reactivity over the course of stress.

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Acknowledgements

This work was supported by the UCLA Research Program for Psychobiological Sciences T32 MH 17140 (Leuchter) and the UCLA Clinical Translational Science Institute UL1TR000124 (Rozenman). The authors would like to acknowledge and thank the children and their parents who participated in this research.

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  1. Division of Child and Adolescent Psychiatry, UCLA Semel Institute for Neuroscience and Human Behavior, 760 Westwood Plaza, 67-455, Los Angeles, CA, 90095, USA

    Michelle Rozenman, Alexandra Sturm, James T. McCracken & John Piacentini

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  1. Michelle Rozenman
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  2. Alexandra Sturm
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Correspondence to Michelle Rozenman.

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Rozenman, M., Sturm, A., McCracken, J.T. et al. Autonomic arousal in anxious and typically developing youth during a stressor involving error feedback. Eur Child Adolesc Psychiatry 26, 1423–1432 (2017). https://doi.org/10.1007/s00787-017-1001-3

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  • DOI: https://doi.org/10.1007/s00787-017-1001-3

Keywords

  • Anxiety
  • Child
  • Adolescent
  • Psychophysiology
  • Heart rate
  • Stress