Skip to main content

Advertisement

Log in

Would some cannabinoids ameliorate symptoms of autism?

  • Letter to the Editor
  • Published:
European Child & Adolescent Psychiatry Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Meyer-Lindenberg A, Domes G, Kirsch P, Heinrichs M (2011) Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine. Nat Rev Neurosci 12:524–538

    Article  PubMed  CAS  Google Scholar 

  2. Green JJ, Hollander E (2010) Autism and oxytocin: new developments in translational approaches to therapeutics. Neurotherapeutics 7:250–257

    Article  PubMed  CAS  Google Scholar 

  3. Andari E, Duhamel JR, Zalla T, Herbrecht E, Leboyer M, Sirigu A (2010) Promoting social behavior with oxytocin in high-functioning autism spectrum disorders. Proc Natl Acad Sci USA 107:4389–4394

    Article  PubMed  CAS  Google Scholar 

  4. Sala M, Braida D, Lentini D et al (2011) Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: a neurobehavioral model of autism. Biol Psychiatry 69:875–882

    Article  PubMed  CAS  Google Scholar 

  5. Wainwright A, Rutter AR, Seabrook GR, Reilly K, Olivier KR (2004) Discrete expression of TRPV2 within the hypothalamo-neurohypophysial system: implications for regulatory activity within the hypothalamic–pituitary–adrenal axis. J Comp Neurol 474:24–42

    Article  PubMed  Google Scholar 

  6. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Peterson-Zeitz KR (2000) Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288:306–313

    Article  PubMed  CAS  Google Scholar 

  7. Qin N, Neeper MP, Liu Y, Hutchinson TL, Lubin ML, Flores CM (2008) TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons. J Neurosci 28:6231–6238

    Article  PubMed  CAS  Google Scholar 

  8. Scuderi C, Filippis DD, Iuvone T, Blasio A, Steardo A, Esposito G (2009) Cannabidiol in medicine: a review of its therapeutic potential in CNS disorders. Phytother Res 23:597–602

    Article  PubMed  CAS  Google Scholar 

  9. Onaivi ES, Benno R, Halpern T et al (2011) Consequences of cannabinoid and monoaminergic system disruption in a mouse model of autism spectrum disorders. Curr Neuropharmacol 9:209–214

    Article  PubMed  CAS  Google Scholar 

  10. Belzung C, Leman S, Vourc’h P, Andres C (2005) Rodents model for autism: a critical review. Drug Discov Today Dis Models 2:93–101

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rami Bou Khalil.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bou Khalil, R. Would some cannabinoids ameliorate symptoms of autism?. Eur Child Adolesc Psychiatry 21, 237–238 (2012). https://doi.org/10.1007/s00787-012-0255-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00787-012-0255-z

Keywords

Navigation