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Mapping the microbiological diversity of odontogenic abscess: are we using the right drugs?

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Abstract

Objectives

The aim of this study was categorizing the microbial flora and susceptibility to antibiotics and to clarify to which degree the empiric administered antibiotics are suitable for therapy.

Materials and methods

A 3.5-year retrospective study evaluated hospital records of 206 patients who suffered from head and neck infections of odontogenic origin. All patients underwent surgical incision and drainage and received intravenous antibiotics and inpatient treatment. The specimens were obtained by performing a swab.

Results

Two hundred six patients were included with 251 strains isolated (1.22 per patient). One hundred eight strains showed antibiotic resistance. Eighty-seven patients showed at least one bacterial strain that showed antibiotic resistance (42.2%). The most frequent isolated bacteria were Streptococcus spp. (n = 116), with a high rate of antibiotic resistance (50.8%). We investigated 205 cases of antibiotic resistance in 87 subjects. Nine bacterial strains showed no susceptibility to unacid (4.3%) and 36 strains to clindamycin (17.5%).

Conclusion

Antibiotic resistance against clindamycin was rather high. The distribution of the afflicted spaces and isolated bacteria was alike recent findings. It is mandatory to understand that immediate surgical treatment in terms of incision and drainage is the basis in abscess treatment. Antibiotic treatment is adjunct therapy.

Clinical relevance

Streptococcus species were the most frequently identified bacteria presenting antibiotic resistance in more than 50%. Increased resistant rates for clindamycin require reconsiderations regarding an empiric antibiotic treatment.

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Authors and Affiliations

  1. Department of Oral & Maxillofacial Plastic Surgery, University Hospital Bonn, Venusberg Campus 1, Haus 11, 2. OG, D-53127, Bonn, Germany

    Nils Heim, Benedict Jürgensen, Franz-Josef Kramer & Valentin Wiedemeyer

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  1. Nils Heim
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  2. Benedict Jürgensen
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  3. Franz-Josef Kramer
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  4. Valentin Wiedemeyer
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Correspondence to Nils Heim.

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Heim, N., Jürgensen, B., Kramer, FJ. et al. Mapping the microbiological diversity of odontogenic abscess: are we using the right drugs?. Clin Oral Invest 25, 187–193 (2021). https://doi.org/10.1007/s00784-020-03350-0

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