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Carious lesion activity assessment in clinical practice: a systematic review

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Abstract

Objectives

The objective of the manuscript is to systematically review the different techniques developed for activity assessment of coronal carious lesions (AACCL) in clinical settings.

Materials and methods

A search of PubMed identified original articles in English reporting on the different concepts/tools for AACCL in clinical settings and, when available, data related to their in vivo/in situ validation in terms of sensitivity, specificity, inter- and intra-examiner reproducibilities, area under the receiving operating curve, positive predictive value, negative predictive value, and relative risk of lesion progression.

Results

The present review included 25 articles. Four groups of techniques are available (1) systems based on combinations of visual and tactile criteria; devices based on (2) pH assessment, (3) fluorescence, or (4) bioluminescence. The most studied systems are those based on combinations of visual and tactile parameters when bioluminescence suffers from the lack of in vivo evaluation. Validation studies showed a wide disparity among protocols in terms of populations, dentitions, teeth surfaces, study design, the gold standard, and validation criteria.

Conclusion

There is a need for definition and harmonization of standards for activity assessment-related concepts/tools, as well as further investigations for in vivo validation of newly developed tools.

Clinical relevance

Carious lesion activity is an important component to be taken into account when making decisions as to appropriate clinical caries management. The development and use of validated techniques which are easy to use in everyday dental practice are important.

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Authors and Affiliations

  1. CROC EA 4847, Université Clermont Auvergne, F-63100, Clermont-Ferrand, France

    Noémie Drancourt, Valérie Roger-Leroi & Sophie Doméjean

  2. Service d’Odontologie, CHU Estaing Clermont-Ferrand, F-63003 cedex 1, Clermont-Ferrand, France

    Noémie Drancourt, Valérie Roger-Leroi & Sophie Doméjean

  3. Dental Innovation and Translation Centre, King’s College London Dental Institute, London, UK

    Stefania Martignon & Nigel Pitts

  4. UNICA - Caries Research Unit, Research Vice-rectory, Universidad El Bosque, Bogotá, Colombia

    Stefania Martignon

  5. Dental School, Department of Orthodontics, Philipps University Marburg, Georg-Voigt Str. 3, D-35039, Marburg, Germany

    Anahita Jablonski-Momeni

  6. UFR d’Odontologie, 2 rue de Braga, 63100, Clermont-Ferrand, France

    Sophie Doméjean

Authors
  1. Noémie Drancourt
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  2. Valérie Roger-Leroi
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  3. Stefania Martignon
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  6. Sophie Doméjean
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Correspondence to Sophie Doméjean.

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Drancourt, N., Roger-Leroi, V., Martignon, S. et al. Carious lesion activity assessment in clinical practice: a systematic review. Clin Oral Invest 23, 1513–1524 (2019). https://doi.org/10.1007/s00784-019-02839-7

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  • DOI: https://doi.org/10.1007/s00784-019-02839-7

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