Oral health-related quality of life is associated with disease specific parameters in patients with ankylosing spondylitis
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The aim of this cross-sectional study was to investigate oral health-related quality of life (OHRQoL) in patients with ankylosing spondylitis (AS) and its association to oral health as well as AS specific parameters.
Patients with AS and a healthy control group (HC) were included and examined. The oral examination included decayed-, missing-, and filled-teeth index (DMF-T) as well as assessment of periodontal probing depth and clinical attachment loss to classify patients into healthy/mild, moderate, or severe periodontitis. Furthermore, the German short form of the oral health impact profile (OHIP G14) was used.
A total of 50 patients each group (age: AS, 47.18 ± 15.67; HC, 55.82 ± 10.56; p < 0.01, gender male: AS, 52%; HC, 46%; p = 0.69) was included. AS patients showed worse D-T (p < 0.01) and periodontal condition (p = 0.01). The OHIP G14 score was clinically relevant and statistically significant higher in AS compared to HC (AS, 6.2 [2; 0–10.75]; HC, 1.7 [0; 0–2.0]; < 0.01). Only in HC, an association of OHIP G14 to DMF-T (p = 0.01) and M-T (p = 0.01) was found, while the OHIP G14 in AS group was not associated to oral health parameters. Within the AS group, the majority of investigated AS specific parameters were statistically significant and clinically relevant associated to OHIP G14 scores (pi < 0.05).
Patients with AS show worse OHRQoL compared to HC, irrespective of oral status. The high general disease burden might affect OHRQoL, making an increased attention of these patients in dental care, especially considering psychological aspects, necessary.
Increased consideration of psychosocial and disease related aspects in dental care of AS patients appear recommendable.
KeywordsOHIP G14 Oral health-related quality of life Ankylosing spondylitis Oral health
We would like to thank Dr. Tanja Kottmann of the Clinical Research Organization, Hamm, Germany, for the statistical analysis.
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
The study was reviewed and approved by the Ethics Committee of the University Medical Center in Goettingen, Germany (application No. DOK_296_2015).
Patients were informed verbally and in writing about the study and gave written informed consent.
- 1.Yang X, Fan D, Xia Q, Wang M, Zhang X, Li X, Cai G, Wang L, Xin L, Xu S, Pan F (2016) The health-related quality of life of ankylosing spondylitis patients assessed by SF-36: a systematic review and meta-analysis. Qual Life Res 25(11):2711–2723. https://doi.org/10.1007/s11136-016-1345-z CrossRefPubMedGoogle Scholar
- 12.Kang EH, Lee JT, Lee HJ, Lee JY, Chang SH, Cho HJ, Choi BY, Ha YJ, Park KU, Song YW, van Dyke TE, Lee YJ (2015) Chronic periodontitis is associated with spinal dysmobility in patients with ankylosing spondylitis. J Periodontol 86(12):1303–1313. https://doi.org/10.1902/jop.2015.150202 CrossRefPubMedGoogle Scholar
- 19.Mühlberg S, Jäger J, Krohn-Grimberghe B, Patschan S, Mausberg RF, Schmalz G et al. (2017) Oral health-related quality of life depending on oral health in patients with rheumatoid arthritis. Clin Oral Investig. doi: https://doi.org/10.1007/s00784-017-2068-4
- 20.Schmalz G, Wendorff H, Marcinkowski A, Weinreich G, Teschler H, Haak R et al. (2017). Oral health related quality of life depending on oral health and specific factors in patients after lung transplantation. Clin Respir J. doi: https://doi.org/10.1111/crj.12625
- 24.WHO (1997) World Health Organisation: oral health surveys, basic methods, 4th edn. WHO; Oral Health Unit, GenfGoogle Scholar
- 28.John MT, Micheelis W, Biffar R (2004) Reference values in oral health-related quality of life for the abbreviated version of the oral health impact profile. Swiss Dent J 114:784–791Google Scholar
- 29.Reissmann D, Krautz M, Schierz O, John MT, Rudolph M, Szentpétery A (2008) Assessment of clinically significant changes in oral health. German Dent J 63:668–680Google Scholar
- 31.Schierz O, John MT, Reissmann DR, Mehrstedt M, Szentpétery A (2008) Comparison of perceived oral health in patients with temporomandibular disorders and dental anxiety using oral health-related quality of life profiles. Qual Life Res 17(6):857–866. https://doi.org/10.1007/s11136-008-9360-3 CrossRefPubMedGoogle Scholar