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Evaluation of the mandibular volume and correlating variables in patients affected by unilateral and bilateral cleft lip and palate: a cone-beam computed tomography study

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Abstract

Objectives

The aims of the present study were to evaluate the mandibular volume in patients affected by unilateral (UCLP) and bilateral cleft lip and palate (BCLP) and to compare the findings with a well-matched normal occlusion sample without cleft.

Materials and methods

The study sample consisted of 66 patients divided into UCLP (24 patients; mean age, 14.46 ± 3.24 years), BCLP (17 patients; mean age, 14.28 ± 2.85 years), and control (25 patients; mean age, 14.40 ± 2.81 years) groups. The volume of the mandible including the condyle and the roots of the teeth and craniofacial measurements were performed using cone-beam computed tomography and analyzed using the one-way variance analysis and post hoc Tukey’s tests. Regression analyses were used to evaluate the relationships of the measurements and the mandibular volume.

Results

Patients affected by UCLP and BCLP had similar craniofacial features (p > 0.05), including decreased SNB, Co-A, Co-Gn, Co-Go, and Go-Gn and increased ANB and SN-MP measurements compared to the control group. Both UCLP and BCLP groups had decreased values of mandibular volume compared to the normal occlusion group, while these differences were found to be statistically insignificant (p > 0.05). Co-Go (Beta = 0.420; p = 0.014) and Co-Gn variables (Beta = 0.708; p = 0.045) were positively correlated with mandibular volume, while SNB (Beta = −0.669; p = 0.044) and SN-MP (Beta = −0.358; p = 0.049) variables were negatively correlated (R 2 = 60.3 and p = 0.000).

Conclusion

Mandibular volume insignificantly differs in cleft patients (p > 0.05), and the variables of Co-Go, Co-Gn, SNB, and SN-MP significantly correlate with the volume.

Clinical relevance

This article investigates mandibular volume in patients affected by UCLP and BCLP that has never been investigated in the literature. The present study showed that both UCLP and BCLP groups had insignificantly decreased values of mandibular volume compared to the normal occlusion group.

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Author information

Authors and Affiliations

  1. Department of Orthodontics, Faculty of Dentistry, Akdeniz University, Antalya, Turkey

    Mevlut Celikoglu

  2. Department of Orthodontics, Faculty of Dentistry, Selcuk University, Konya, Turkey

    Faruk Izzet Ucar & Mehmet Akin

  3. Department of Orthodontics, Faculty of Dentistry, Ordu University, Ordu, Turkey

    Suleyman Kutalmış Buyuk

  4. Department of Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, Antalya, Turkey

    Salih Celik

  5. Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Erciyes University, Kayseri, Turkey

    Ahmet Ercan Sekerci

Authors
  1. Mevlut Celikoglu
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  2. Faruk Izzet Ucar
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  3. Suleyman Kutalmış Buyuk
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  4. Salih Celik
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  5. Ahmet Ercan Sekerci
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  6. Mehmet Akin
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Corresponding author

Correspondence to Suleyman Kutalmış Buyuk.

Ethics declarations

All participating subjects signed the informed consent. The requirements of the Helsinki Declaration were observed. This retrospective study was approved by the local ethics committee of Erciyes University.

Conflict of interest

The authors declare that they have no competing interests.

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Celikoglu, M., Ucar, F.I., Buyuk, S.K. et al. Evaluation of the mandibular volume and correlating variables in patients affected by unilateral and bilateral cleft lip and palate: a cone-beam computed tomography study. Clin Oral Invest 20, 1741–1746 (2016). https://doi.org/10.1007/s00784-015-1651-9

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  • DOI: https://doi.org/10.1007/s00784-015-1651-9

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