Evaluation of light-touch sensation in the buccal mucosa of leprosy patients
- 107 Downloads
The aim of this study is to evaluate the light-touch sensation of the oral mucosa in leprosy patients.
Materials and methods
A cross-sectional study included 228 adults, 133 being leprosy patients and 95 normal controls. To assess light-touch sensation, the five-filament standard Semmes–Weinstein kit in eight regions of the oral mucosa was used. Chi-square test was used to verify the differences in responses between the studied groups.
Normal sensation was predominant in both groups, and diminished sensation was found also in the nonleprosy group. Normal controls showed diminished light-touch sensation in at least one point, which may be attributed to the definition of sensation normality. The chi-square test revealed no significant difference between the two groups (p = 0.43171). Severe diminished sensation was detected only in the leprosy group.
It is concluded that altered light-touch sensation in the oral cavity may not be a common feature in leprosy.
Decreased or lost sensation in skin lesions is a paramount in leprosy diagnosis; however, clinicians must be aware that this seems not to be true in the oral mucosa in leprosy cases for diagnosis purpose.
KeywordsBuccal mucosa Leprosy Semmes–Weinstein filament Sensory test Oral physiology
This study was partially supported by the Paulista Foundation Against Leprosy.
Conflicts of interest
No conflicts of interest declared.
- 1.Sengupta U (2001) Immunopathology of leprosy: a state of the art. Int J Lepr 69:S36–S41Google Scholar
- 2.Sarno EN, Pessolani MCV (2001) Oldest and most feared disease. Lancet Suppl S39:358Google Scholar
- 3.Neville BW, Damm DD, Allen CM et al (1995) Oral and maxillofacial pathology. Saunders, PhiladelphiaGoogle Scholar
- 6.Tonello AS, Virmond MCL, Belmonte P, Zuchieri MABO, Monti JF, Belmonte G (2007) Oral health in leprosy patients. Indian J Lepr 79:37–45Google Scholar
- 8.Ridley DS, Jopling WH (1966) Classification of leprosy according to immunity. A five-group system. Int J Lepr 34:255–273Google Scholar
- 11.Watanabe Y, Ishikawa T, Kino K et al (2005) Relationship between oral sensory thresholds and depressive moods. J Med Dent Sci 52:72–80Google Scholar
- 14.Sawyer DR, Alagumba LN, Lehnert JF (1987) Facial and oral manifestations of leprosy: an evaluation of the one hundred and four cases. J Oral Med 42:143–149Google Scholar
- 17.Anuja N, Sherlin HJ, Anandan S, Mani NJ, Malathi N (2011) Subclinical changes of oral mucosa in Hansen’s disease—a histopathological and immunohistochemical study. Biol Med 3:31–42Google Scholar
- 18.Fokken WJ, Gijs SJ, Trenite N, Virmond M, Kleinjanvera ALG, Andrade NV (1998) The nose in leprosy: immunohistology of the nasal mucosa. Int J Lepr 66:328–337Google Scholar
- 23.Loewe IJ, Boliek CA, Harris J, Seikaly H, Rieger JM (2010) Sensation and function after tongue reconstruction. Head Neck 32:85–95Google Scholar
- 25.Costa Nery JA, Oliveira M, Cuzzi T, Silva M (2003) Oral lesions in leprosy. Indian J Dermatol Venereol Leprol 69:381–385Google Scholar