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Clinical Oral Investigations

, Volume 18, Issue 8, pp 1949–1961 | Cite as

Cortical activation resulting from the stimulation of periodontal mechanoreceptors measured by functional magnetic resonance imaging (fMRI)

  • P. Habre-HallageEmail author
  • L. Dricot
  • L. Hermoye
  • H. Reychler
  • D. van Steenberghe
  • R. Jacobs
  • C. B. Grandin
Original Article

Abstract

Objective

To describe the normal cortical projections of periodontal mechanoreceptors.

Material and methods

A device using von Frey filaments delivered 1-Hz punctate tactile stimuli to the teeth during fMRI. In a block design paradigm, tooth (T) 11 and T13 were stimulated in ten volunteers and T21 and T23 in ten other subjects. Random-effect group analyses were performed for each tooth, and differences between teeth were examined using ANOVA.

Results

The parietal operculum (S2) was activated bilaterally for all teeth; the postcentral gyrus (S1) was activated bilaterally for T21 and T23 and contralaterally for T11 and T13. In the second-level analysis including the four teeth, we found five clusters: bilateral S1 and S2, and left inferior frontal gyrus, with no difference between teeth in somatosensory areas. However, the ANOVA performed on the S1 clusters found separately in each tooth showed that S1 activation was more contralateral for the canines.

Conclusion

One-hertz mechanical stimulation activates periodontal mechanoreceptors and elicits bilateral cortical activity in S1 and S2, with a double representation in S2, namely in OP1 and OP4.

Clinical relevance

The cortical somatotopy of periodontal mechanoreceptors is poorly described. These findings may serve as normal reference to further explore the cortical plasticity induced by periodontal or neurological diseases.

Keywords

fMRI Somatosensory cortex Trigeminal Dental Periodontal mechanoreceptor 

Notes

Conflict of interest

The authors declare that they have no conflict of interests. No external funding, apart from the support of the authors’ institution, was available for this study.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • P. Habre-Hallage
    • 1
    • 2
    Email author
  • L. Dricot
    • 3
  • L. Hermoye
    • 4
  • H. Reychler
    • 5
  • D. van Steenberghe
    • 6
  • R. Jacobs
    • 2
  • C. B. Grandin
    • 3
    • 7
  1. 1.Department of Prosthodontics, Faculty of DentistrySaint Joseph UniversityBeirutLebanon
  2. 2.Oral Imaging Center, Faculty of MedicineCatholic University of LeuvenLeuvenBelgium
  3. 3.Institute of NeurosciencesUniversité Catholique de LouvainBrusselsBelgium
  4. 4.Imagilys SPRLBrusselsBelgium
  5. 5.Department of Oral and Maxillofacial SurgerySt Luc University Hospital, Université Catholique de LouvainBrusselsBelgium
  6. 6.Faculty of MedicineCatholic University of LeuvenLeuvenBelgium
  7. 7.Medical Imaging DepartmentSt Luc University HospitalBrusselsBelgium

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