Skip to main content
Log in

Eosinophilic granulomatosis with polyangiitis presenting as acute sciatic nerve neuropathy resembling lumbar disease

  • Case Report
  • Published:
Journal of Orthopaedic Science

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

References

  1. Churg J, Strauss L. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Am J Pathol. 1951;27:277–301.

    CAS  PubMed Central  PubMed  Google Scholar 

  2. Oka N, Kawasaki T, Matsui M, Shigematsu K, Unuma T, Sugiyama H. Two subtypes of Churg–Strauss syndrome with neuropathy: the roles of eosinophils and ANCA. Mod Rheumatol. 2011;21:290–5.

    Article  PubMed  Google Scholar 

  3. Lanham JG, Elkon KB, Pusey CD, Hughes GR. Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg–Strauss syndrome. Medicine (Baltimore). 1984;63:65–81.

    Article  CAS  PubMed  Google Scholar 

  4. Pavone L, Grasselli C, Chierici E, Maggiore U, Garini G, Ronda N, Manganelli P, Pesci A, Rioda WT, Tumiati B, Pavesi G, Vaglio A, Buzio C. Secondary, Primary Vasculitides Study Group. Outcome and prognostic factors during the course of primary small-vessel vasculitides. J Rheumatol. 2006;33:1299–306.

    PubMed  Google Scholar 

  5. Guillevin L, Lhote F, Gayraud M, Cohen P, Jarrousse B, Lortholary O, Thibult N, Casassus P. Prognostic factors in polyarteritis nodosa and Churg–Strauss syndrome. A prospective study in 342 patients. Medicine (Baltimore). 1996;75:17–28.

    Article  CAS  Google Scholar 

  6. Mukhtyar C, Guillevin L, Cid MC, Dasgupta B, de Groot K, Gross W, Hauser T, Hellmich B, Jayne D, Kallenberg CG, Merkel PA, Raspe H, Salvarani C, Scott DG, Stegeman C, Watts R, Westman K, Witter J, Yazici H, Luqmani R, European Vasculitis Study Group. EULAR recommendations for the management of primary small and medium vessel vasculitis. Ann Rheum Dis. 2009;68:310–7.

    Article  CAS  PubMed  Google Scholar 

  7. Pfirrmann CW, Metzdorf A, Zanetti M, Hodler J, Boos N. Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976). 2001;26:1873–8.

  8. Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP, Calabrese LH, Edworthy SM, Fauci AS, Leavitt RY. The American College of Rheumatology 1990 criteria for the classification of Churg–Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum. 1990;33:1094–100.

    Article  CAS  PubMed  Google Scholar 

  9. Hashimoto H, Yano T, Abe T. Allergic granulomatosis angiitis: manual of diagnosis and treatment about refractory vasculitis: investigation and research about refractory vasculitis. Jpn Minist Health Labour Welf. 2002:27–29 (in Japanese).

  10. Ribi C, Cohen P, Pagnoux C, Mahr A, Arene JP, Lauque D, Puechal X, Letellier P, Delaval P, Cordier JF, Guillevin L, French Vasculitis Study Group. Treatment of Churg–Strauss syndrome without poor-prognosis factors: a multicenter, prospective, randomized, open-label, study of seventy-two patients. Arthritis Rheum. 2008;58:586–94.

    Article  CAS  PubMed  Google Scholar 

  11. Vital A, Vital C, Viallard JF, Ragnaud JM, Canron MH, Lagueny A. Neuro-muscular biopsy in Churg–Strauss syndrome: 24 cases. J Neuropathol Exp Neurol. 2006;65:187–92.

    Article  PubMed  Google Scholar 

  12. Hashimoto H, Yano T, Abe T. Epidemiologic investigation of vasculitis affecting small and medium sized vessels. Japanese Ministry of Health, Labour and Welfare. 1996:9–21 (in Japanese).

  13. Rothenberg ME. Mechanisms of disease: eosinophilia. N Engl J Med. 1998;338:1592–600.

    Article  CAS  PubMed  Google Scholar 

  14. Sinico RA, Di Toma L, Maggiore U, Bottero P, Radice A, Tosoni C, Grasselli C, Pavone L, Gregorini G, Monti S, Frassi M, Vecchio F, Corace C, Venegoni E, Buzio C. Prevalence and clinical significance of antineutrophil cytoplasmic antibodies in Churg–Strauss syndrome. Arthritis Rheum. 2005;52:2926–35.

    Article  CAS  PubMed  Google Scholar 

  15. Chumbley LC, Harrison EG Jr, DeRemee RA. Allergic granulomatosis and angiitis (Churg–Strauss syndrome). Report and analysis of 30 cases. Mayo Clin Proc. 1977;52:477–84.

    CAS  PubMed  Google Scholar 

  16. Slifman NR, Loegering DA, Mckean DJ, Gleich GJ. Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein. J Immunol. 1986;137(9):2913–7.

    CAS  PubMed  Google Scholar 

  17. Watts RA, Lane SE, Bentham G, Scott DG. Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom. Arthritis Rheum. 2000;43:414–9.

    Article  CAS  PubMed  Google Scholar 

  18. Guillevin L, Cohen P, Gayraud M, Lhote F, Jarrousse B, Casassus P. Churg–Strauss syndrome. Clinical study and long-term follow-up of 96 patients. Medicine (Baltimore). 1999;78:26–37.

    Article  CAS  Google Scholar 

  19. Watts RA, Gonzalez-Gay MA, Lane SE. Geoepidemiology of systemic vasculitis: comparison of the incidence in two regions of Europe. Ann Rheum Dis. 2001;60:170–2.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  20. Noth I, Strek ME, Leff AR. Churg–Strauss syndrome. Lancet. 2003;361:587–94.

    Article  PubMed  Google Scholar 

  21. Tsurikisawa N, Tsuburai T, Saito H. A retrospective study of bronchial hyperresponsiveness in patients with asthma before the onset of Churg–Strauss syndrome. Allergy Asthma Proc. 2007;28:336–43.

    Article  PubMed  Google Scholar 

  22. Dyck PJ, Conn DL, Okazaki H. Necrotizing angiopathic neuropathy. Three-dimensional morphology of fiber degeneration related to sites of occluded vessels. Mayo Clin Proc. 1972;47:461–75.

    CAS  PubMed  Google Scholar 

  23. Young JD, Peterson CG, Venga P, Cohn ZA. Mechanism of membrane damage mediated by human eosinophil cationic protein. Nature. 1986;321(6070):613–6.

    Article  CAS  PubMed  Google Scholar 

  24. Lazzarin P. Churg–Strauss syndrome presenting as polymyositis: report of a case. Reumatismo. 2009;61(2):140–4.

    CAS  PubMed  Google Scholar 

  25. Andre MC, Fraga A, Duarte R, Filipe P, Almeida A, Marques Gomes MA. Churg–Strauss syndrome: a disabling disease. Acta Med Port. 2011;24:853–6.

    CAS  PubMed  Google Scholar 

  26. Hettler A, Bohm J, Pretzsch M, von Salis-Soglio G. Extragenital endometriosis leading to piriformis syndrome. Nervenarzt. 2006;77:474–7 (in German).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

The authors are indebted to Dr. Clifford A. Kolba (EdD, DO, MPH) and Associate Professor Edward F. Barroga (DVM, PhD) of the Department of International Medical Communications of Tokyo Medical University for their editorial review of the English manuscript.

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kazuma Murata.

About this article

Cite this article

Murata, K., Endo, K., Nishimura, H. et al. Eosinophilic granulomatosis with polyangiitis presenting as acute sciatic nerve neuropathy resembling lumbar disease. J Orthop Sci 20, 224–228 (2015). https://doi.org/10.1007/s00776-013-0437-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00776-013-0437-7

Keywords

Navigation