8th Asian Biological Inorganic Chemistry Conference
A significant number of contributions focused on imaging and sensing techniques in Bioinorganic Chemistry. In this issue, Kazuya Kikuchi summarizes recent developments of fluorescent dyes for super-resolution microscopy (doi: 10.1007/s00775-016-1435-y), while Fuyi Wang uses secondary ion mass spectrometry imaging to visualize metallodrugs in single cells (doi: 10.1007/s00775-017-1462-3). Peter Lay reports studies on the reason for the high cytotoxicity observed for vanadium(IV) complexes (doi: 10.1007/s00775-017-1453-4), while Hongzhe Sun and Hongyan Li investigate the mechanism of action responsible for the antimicrobial activity of bismuth(III) compounds (doi: 10.1007/s00775-017-1452-5). Peng Chen reports on his group’s efforts to obtain crystal structures of DNA-bound forms of multiple-antibiotic-resistance regulator (MarR), which controls, among other things, bacterial resistance to antibiotics (doi: 10.1007/s00775-017-1442-7).
As in many Biological Inorganic Chemistry conferences, significant contributions to the understanding of metalloproteins and their biological functions were reported. This special issue includes Takashi Hayashi’s work on the reconstitution of horseradish peroxidase with cobalt tetradehydrocorrin to obtain a cobalamin-dependent enzyme model (doi: 10.1007/s00775-017-1458-z). Shun Hirota discusses the effect of Met80 heme coordination on cyt c domain swapping (doi: 10.1007/s00775-017-1446-3), and Mio Kondo and Shigeyuki Masaoka describe iron porphyrin complexes as bioinspired catalysts for CO2 reduction (doi: 10.1007/s00775-017-1438-3), while Jing Zhang and Jun-Long Zhang present studies on linear tetrapyrrole as ligands and analogues to porphyrin and corroles (doi: 10.1007/s00775-017-1444-5). The reactivity of other important biological ligands, i.e., catechols, in siderophores and synthetic analogues as well as of Dopa-containing mussel foot proteins is reviewed by Alison Butler (doi: 10.1007/s00775-017-1451-6).
In a contribution on Se speciation in the environment, Debbie Crans points out the importance of speciation for toxicity (doi: 10.1007/s00775-017-1457-0). Elizabeth New and Trevor Hambley present their work on the cisplatin interaction with the copper transporter CTR1, which has been shown to play a role in the uptake of cisplatin into cancer cells (doi: 10.1007/s00775-017-1467-y), and finally, both Paul Bernhardt’s group and my group report work on Co complexes as tools for the spectroelectrochemical investigation of heme proteins and for capillary zone electrophoresis, respectively (doi: 10.1007/s00775-016-1427-y, doi: 10.1007/s00775-016-1426-z).
I hope to see many of you again at AsBIC-9 in Singapore in 2018 (http://www.asbic9.org) and that you enjoy the selection of papers presented in this special issue of the Journal of Biological Inorganic Chemistry.