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Biocompatible hydroxyapatite nanoparticles as a redox luminescence switch

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Abstract

A redox luminescence switch was prepared by doping hydroxyapatite nanoparticles with CePO4:Tb. The resulting multifunctional material exhibits good biocompatibility, biological affinity, and potential drug-carrying capability. The luminescent hydroxyapatite nanoparticles may find important applications in biomedical diagnostics, drug delivery, and biological sensors.

Graphical abstract

This work demonstrated a biocompatible redox luminescence switch based on hydroxyapatite nanoparticles. The as-synthesized multifunctional nanoparticles have a large surface area and exhibit high biological affinity. This study will be quite relevant for developing a new system that may be applied in studying enzyme or protein activities based on fluorescent nanoparticles.

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Acknowledgments

This study was supported by the Foundation of Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, State Key Laboratory of Applied Organic Chemistry, and the NSFC (20171019).

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Authors and Affiliations

  1. Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, People’s Republic of China

    Hongyan Liu, Pinxian Xi, Guoqiang Xie, Fengjuan Chen, Zhenpeng Li & Zhengzhi Zeng

  2. School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, People’s Republic of China

    Decheng Bai

Authors
  1. Hongyan Liu
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  2. Pinxian Xi
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  3. Guoqiang Xie
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  4. Fengjuan Chen
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  5. Zhenpeng Li
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  6. Decheng Bai
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  7. Zhengzhi Zeng
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Corresponding authors

Correspondence to Decheng Bai or Zhengzhi Zeng.

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Liu, H., Xi, P., Xie, G. et al. Biocompatible hydroxyapatite nanoparticles as a redox luminescence switch. J Biol Inorg Chem 16, 1135–1140 (2011). https://doi.org/10.1007/s00775-011-0815-6

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  • DOI: https://doi.org/10.1007/s00775-011-0815-6

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