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Bone mineral density of proximal femur and spine in Korean children between 2 and 18 years of age

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Abstract

Ethnic factors affect bone mass acquisition during childhood. The aim of our study was to establish normative data for bone mineral content (BMC) and bone mineral density (BMD) in healthy Korean children and adolescents, using 446 lumbar spine scans (224 males and 222 females) and 364 proximal femur scans (181 males and 183 females) of healthy children between ages 2 and 18 years measured by dual-energy X-ray absorptiometry using Hologic QDR Discovery A 2004. There was an increase in both BMC and BMD during early childhood, acceleration during the adolescence spurt, and a slower increase later. Until 11 years of age, both male and female BMC and BMD were not statistically different. There was a rapid increase in both BMC and BMD in females earlier than in males, and later males caught up with the females and overshot the female values. When compared with Canadian children, BMD and BMC of total proximal femur was found to be more and BMD and BMC of total lumbar spine to be less at some ages. Tanner's stage was significantly associated with BMD and BMC of spine and proximal femur in males and BMC of spine in females in the first three Tanner's stages. Height, body weight, fat content, and body mass index influenced BMC and BMD at different sites by variable amount. Hence, the values presented in this study should be used as reference values in Korean children and adolescents.

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Author information

Authors and Affiliations

  1. Department of Orthopedic Surgery, Konkuk University Hospital, Seoul, Korea

    Suk-Ha Lee

  2. Department of Orthopedic Surgery, Korea University, Guro Hospital, Seoul, Korea

    Sameer Shrikrishna Desai

  3. Department of Orthopedic Surgery, Korea University, Guro Hospital, Seoul, Korea

    Gautam Shetty

  4. Department of Orthopedic Surgery, Korea University, Guro Hospital, Rave Diseases Institute, 80, Guro-Dong, Guro-Gu, Seoul, 152-703, Korea

    Hae-Ryong Song

  5. Department of Orthopedic Surgery, Dongguk University International Hospital, Ilsan, Korea

    Seok-Hyun Lee

  6. Department of Orthopedic Surgery, Korea University, Guro Hospital, Seoul, Korea

    Chung-Yong Hur

  7. Department of Statistics, Korea University, Seoul, Korea

    Jong-Chan Lee

Authors
  1. Suk-Ha Lee
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  2. Sameer Shrikrishna Desai
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  3. Gautam Shetty
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  4. Hae-Ryong Song
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  5. Seok-Hyun Lee
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  6. Chung-Yong Hur
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  7. Jong-Chan Lee
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Corresponding author

Correspondence to Hae-Ryong Song.

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Lee, SH., Desai, S., Shetty, G. et al. Bone mineral density of proximal femur and spine in Korean children between 2 and 18 years of age. J Bone Miner Metab 25, 423–430 (2007). https://doi.org/10.1007/s00774-007-0775-7

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  • DOI: https://doi.org/10.1007/s00774-007-0775-7

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