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Secondary hyperparathyroidism as a palpable intrathyroid parathyroid gland in a patient with hypophosphatemic osteomalacia

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Abstract

Secondary hyperparathyroidism is sometimes seen in patients with hypophosphatemic osteomalacia after long-term oral phosphate therapy. Parathyroidectomy is sometimes needed for the correction of hypercalcemia in these patients, and is rarely performed in patients without hypercalcemia. A 46-year-old female patient had hypophosphatemic osteomalacia with unknown cause and secondary hyperparathyroidism. A palpable neck mass developed after long-term oral phosphate therapy. An intrathyroid parathyroid gland was confirmed through partial thyroidectomy and parathyroidectomy. Renal phosphate wasting decreased strongly, and serum parathyroid hormone was in the normal range after the operation. A correction of secondary hyperparathyroidism may partially overcome hyperphosphaturia in some patients with hypophosphatemic rickets.

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Authors and Affiliations

  1. Department of Internal Medicine, Far Eastern Polyclinic, Taipei, Taiwan

    Deng-Huang Su

  2. Department of Internal Medicine, Zhongxiao Branch, Taipei City Hospital, Taipei, and Chung-Hsiao Municipal Hospital, Taipei, Taiwan

    Kuo-Meng Liao

  3. Department of Internal Medicine, Miao-Li General Hospital, Department of Health, Executive Yuan, Miao-Li, Taiwan

    Ying-Chun Chang

  4. Department of Laboratory, National Taiwan University Hospital and National Taiwan University College of Medicine, No. 7 Chung-Shan South Road, Taipei, 100, Taiwan

    Keh-Sung Tsai

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  1. Deng-Huang Su
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  2. Kuo-Meng Liao
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  3. Ying-Chun Chang
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  4. Keh-Sung Tsai
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Correspondence to Keh-Sung Tsai.

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Su, DH., Liao, KM., Chang, YC. et al. Secondary hyperparathyroidism as a palpable intrathyroid parathyroid gland in a patient with hypophosphatemic osteomalacia. J Bone Miner Metab 24, 114–117 (2006). https://doi.org/10.1007/s00774-005-0656-x

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  • DOI: https://doi.org/10.1007/s00774-005-0656-x

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