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Was ist eine Lebensstil limitierende Claudicatio? Patientenberichtete Endpunkte in der Behandlung der peripheren arteriellen Verschlusskrankheit (PAVK)

What is a lifestyle-limiting claudication? Patient-reported endpoints in the treatment of peripheral artery disease (PAD)

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Zusammenfassung

In der Gefäßmedizin gilt die periphere arterielle Verschlusskrankheit (PAVK) als eine der häufigsten Erkrankungen und zudem als wichtiger Risikomarker für kardiovaskuläre Ereignisse und Mortalität. Neben der Verbesserung der Funktionalität und des Beinerhalts stellt auch die Steigerung der gesundheitsbezogenen Lebensqualität ein primäres Behandlungsziel dar. Eine kontinuierliche Messung des patientenberichteten Therapieerfolgs (PROM) unterstützt die Entscheidungsfindung weiterer therapeutischer Maßnahmen und ermöglicht zugleich die Qualitätssicherung in der Behandlung der PAVK. Patientenberichtete Endpunkte können mithilfe von Qualitätsindikatoren (QI), welche den Therapieerfolg aus Sicht des Patienten darstellen, erfasst werden. Eine standardisierte Integration des empfohlenen PROM VascuQoL‑6 in Studien und vaskulären Registern verfolgt das Ziel der internationalen Harmonisierung der patientenberichteten Datenerfassung.

Abstract

Peripheral arterial disease (PAD) is one of the most common diseases in vascular medicine and is also considered an important risk marker for cardiovascular events and mortality. In addition to improving functionality and leg preservation, increasing health-related quality of life is also a primary treatment goal. Continuous measurement of patient-reported outcomes (PROM) supports decision making for further therapeutic interventions and at the same time enables quality assurance in the treatment of PAD. Patient-reported endpoints can be measured using quality indicators (QIs), which represent the success of therapy from the patient’s perspective. A standardized integration of the recommended PROM VascuQoL‑6 in studies and vascular registries pursues the goal of international harmonization of patient-reported data collection.

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Change history

  • 20 January 2023

    Der englische Titel dieses Artikels war fälschlicherweise mit „What is a lifestyle-limiting claudication? Patient-reported endpoints in the treatment of peripheral artery disease (PAV)“ angegeben. Richtig lautet der englische Titel „What is a lifestyle-limiting claudication? Patient-reported endpoints in the treatment of peripheral artery disease (PAD)“.

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Authors and Affiliations

  1. Forschungsgruppe GermanVasc, Hamburg, Deutschland

    Helene Arndt &  Christian-Alexander Behrendt MD FESVS

  2. Klinik für Allgemeine und Endovaskuläre Gefäßchirurgie, Asklepios Klinik Wandsbek, Asklepios Medical School, Hamburg, Deutschland

    Christian-Alexander Behrendt MD FESVS

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  1. Helene Arndt
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Correspondence to Christian-Alexander Behrendt MD FESVS.

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Interessenkonflikt

H. Arndt gibt an, dass kein Interessenkonflikt besteht. C.-A. Behrendt ist Co-Chair der 2024 Clinical Practice Guidelines zur Behandlung der asymptomatischen PAVK und Intermittent Claudication der European Society for Vascular Surgery (ESVS) und Mitglied der Writing Committees bzw. Leitliniensteuergruppen der AWMF-S3-Leitlinien zur Diagnostik und Behandlung der PAVK, der 2023 Clinical Practice Guidelines zu Antithrombotika bei Gefäßkrankheiten der ESVS sowie der fachgesellschaftsübergreifenden Leitlinien zur Behandlung der kritischen Extremitätenischämie und des diabetischen Fußsyndroms der International Working Group of the Diabetic Foot (IWGDF). Er ist medizinisch-wissenschaftlicher Direktor des Deutschen Instituts für Gefäßmedizinische Gesundheitsforschung gGmbH (DIGG) der Deutschen Gesellschaft für Gefäßchirurgie und Gefäßmedizin e.V. (DGG).

Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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Arndt, H., Behrendt, CA. Was ist eine Lebensstil limitierende Claudicatio? Patientenberichtete Endpunkte in der Behandlung der peripheren arteriellen Verschlusskrankheit (PAVK). Gefässchirurgie 28, 229–234 (2023). https://doi.org/10.1007/s00772-022-00963-5

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