Literatur
Clouse WD, Hallett JW Jr., Schaff HV, Gayari MM, Ilstrup DM, Melton LJ 3rd (1998) Improved prognosis of thoracic aortic aneurysms: a population-based study. JAMA 280(22):1926–1929
Kuzmik GA, Sang AX, Elefteriades JA (2012) Natural history of thoracic aortic aneurysms. J Vasc Surg 56(2):565–571
Jacobs MJ, Mommertz G, Koeppel TA, Langer S, Nijenhuis RJ, Mess WH et al (2007) Surgical repair of thoracoabdominal aortic aneurysms. J Cardiovasc Surg (Torino) 48(1):49–58
Coselli JS, LeMaire SA, Preventza O, de la Cruz KI, Cooley DA, Price MD et al (2016) Outcomes of 3309 thoracoabdominal aortic aneurysm repairs. J Thorac Cardiovasc Surg 1515(5):1323–1327. https://doi.org/10.1016/j.jtcvs.2015.12.050
Barratt J, Parajasingam R, Sayers RD, Feehally J (2000) Outcome of acute renal failure following surgical repair of ruptured abdominal aortic aneurysms. Eur J Vasc Endovasc Surg 20(2):163–168
Dennen P, Parikh CR (2007) Biomarkers of acute kidney injury: can we replace serum creatinine? Clin Nephrol 68(5):269–278
Welborn MB, Oldenburg HS, Hess PJ, Huber TS, Martin TD, Rauwerda JA et al (2000) The relationship between visceral ischemia, proinflammatory cytokines, and organ injury in patients undergoing thoracoabdominal aortic aneurysm repair. Crit Care Med 28(9):3191–3197
Fiane AE, Videm V, Lingaas PS, Heggelund L, Nielsen EW, Geiran OR et al (2003) Mechanism of complement activation and its role in the inflammatory response after thoracoabdominal aortic aneurysm repair. Circulation 108(7):849–856
Arnaoutoglou E, Kouvelos G, Papa N, Kallinteri A, Milionis H, Koulouras V et al (2015) Prospective evaluation of post-implantation inflammatory response after EVAR for AAA: influence on patients’ 30 day outcome. Eur J Vasc Endovasc Surg 49(2):175–183
Van Biesen W, Vanholder R, Lameire N (2006) Defining acute renal failure: RIFLE and beyond. Clin J Am Soc Nephrol 1(6):1314–1319
Uchino S, Bellomo R, Goldsmith D, Bates S, Ronco C (2006) An assessment of the RIFLE criteria for acute renal failure in hospitalized patients. Crit Care Med 34(7):1913–1917
Brinkman R, HayGlass KT, Mutch WA, Funk DJ (2015) Acute kidney injury in patients undergoing open abdominal aortic aneurysm repair: a pilot observational trial. J Cardiothorac Vasc Anesth 29(5):1212–1219
Kjeldsen L, Cowland JB, Borregaard N (2000) Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse. Biochim Biophys Acta 1482(1–2):272–283
Makris K, Markou N, Evodia E, Dimopoulou E, Drakopoulos I, Ntetsika K et al (2009) Urinary neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in critically ill multiple trauma patients. Clin Chem Lab Med 47(1):79–82
Price PM, Safirstein RL, Megyesi J (2009) The cell cycle and acute kidney injury. Kidney Int 76(6):604–613
Rodier F, Campisi J, Bhaumik D (2007) Two faces of p53: aging and tumor suppression. Nucleic Acids Res 35(22):7475–7484
Seo DW, Li H, Guedez L, Wingfield PT, Diaz T, Salloum R et al (2003) TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. Cell 114(2):171–180
Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR (2008) Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7. Cell 132(3):363–374
Meersch M, Schmidt C, Van Aken H, Martens S, Rossaint J, Singbartl K et al (2014) Urinary TIMP-2 and IGFBP7 as early biomarkers of acute kidney injury and renal recovery following cardiac surgery. PLoS ONE 9(3):e93460
Gocze I, Koch M, Renner P, Zeman F, Graf BM, Dahlke MH et al (2015) Urinary biomarkers TIMP-2 and IGFBP7 early predict acute kidney injury after major surgery. PLoS ONE 10(3):e120863
Asare Y, Schmitt M, Bernhagen J (2013) The vascular biology of macrophage migration inhibitory factor (MIF). Expression and effects in inflammation, atherogenesis and angiogenesis. Thromb Haemost 109(3):391–398
Schober A, Bernhagen J, Weber C (2008) Chemokine-like functions of MIF in atherosclerosis. J Mol Med 86(7):761–770
Payen D, Lukaszewicz AC, Legrand M, Gayat E, Faivre V, Megarbane B et al (2012) A multicentre study of acute kidney injury in severe sepsis and septic shock: association with inflammatory phenotype and HLA genotype. PLoS ONE 7(6):e35838
Stefaniak J, Schiefer J, Miller EJ, Krenn CG, Baron DM, Faybik P (2015) Macrophage migration inhibitory factor as a potential predictor for requirement of renal replacement therapy after orthotopic liver transplantation. Liver Transpl 21(5):662–669
Kleemann R, Hausser A, Geiger G, Mischke R, Burger-Kentischer A, Flieger O et al (2000) Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature 408(6809):211–216
Al-Abed Y, Dabideen D, Aljabari B, Valster A, Messmer D, Ochani M et al (2005) ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis. J Biol Chem 280(44):36541–36544
Stoppe C, Grieb G, Rossaint R, Simons D, Coburn M, Gotzenich A et al (2012) High postoperative blood levels of macrophage migration inhibitory factor are associated with less organ dysfunction in patients after cardiac surgery. Mol Med 18:843–850
Magovern JA, Singh D, Teekell-Taylor L, Scalise D, McGregor W (2007) Preoperative clinical factors are important determinants of the inflammatory state before and after heart surgery. Asaio J 53(3):316–319
Amar D, Zhang H, Park B, Heerdt PM, Fleisher M, Thaler HT (2007) Inflammation and outcome after general thoracic surgery. Eur J Cardiothorac Surg 32(3):431–434
Roger T, Delaloye J, Chanson AL, Giddey M, Le Roy D, Calandra T (2013) Macrophage migration inhibitory factor deficiency is associated with impaired killing of gram-negative bacteria by macrophages and increased susceptibility to Klebsiella pneumoniae sepsis. J Infect Dis 207(2):331–339
Gombert A, Stoppe C, Foldenauer AC, Schuerholz T, Martin L, Kalder J et al (2017) Macrophage migration inhibitory factor predicts outcome in complex aortic surgery. Int J Mol Sci 18(11):pii: E2374. https://doi.org/10.3390/ijms18112374
Peled E, Melamed E, Portal TB, Axelman E, Norman D, Brenner B et al (2016) Heparanase procoagulant activity as a predictor of wound necrosis following diabetic foot amputation. Thromb Res 139:148–153
Nadir Y, Brenner B (2014) Heparanase multiple effects in cancer. Thromb Res 133(Suppl 2):S90–S94
Rohloff J, Zinke J, Schoppmeyer K, Tannapfel A, Witzigmann H, Mossner J et al (2002) Heparanase expression is a prognostic indicator for postoperative survival in pancreatic adenocarcinoma. Br J Cancer 86(8):1270–1275
Tshomba Y, Kahlberg A, Melissano G, Coppi G, Marone E, Ferrari D et al (2014) Comparison of renal perfusion solutions during thoracoabdominal aortic aneurysm repair. J Vasc Surg 59(3):623–633
Geven C, Bergmann A, Kox M, Pickkers P (2018) Vascular effects of adrenomedullin and the anti-adrenomedullin antibody adrecizumab in sepsis. Shock. https://doi.org/10.1097/SHK.0000000000001103
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A. Gombert, C. Stoppe, L. Martin, P. Keschenau, M.E. Barbati, J. Kalder, J. Grommes und M.J. Jacobs geben an, dass kein Interessenkonflikt besteht.
Dieser Beitrag beinhaltet von den Autoren nach den gültigen ethischen Standards durchgeführte Studien an Tieren. Die notwendigen Zustimmungen der zuständigen Behörden liegen vor. Alle beschriebenen Untersuchungen am Menschen wurden mit Zustimmung der zuständigen Ethik-Kommission, im Einklang mit nationalem Recht sowie gemäß der Deklaration von Helsinki von 1975 (in der aktuellen, überarbeiteten Fassung) durchgeführt. Die Urin- und Blutproben wurden nach entsprechender ausführlicher Aufklärung von Patienten entnommen, die aufgrund eines thorakoabdominellen Aortenaneurysmas operiert worden sind. Von allen beteiligten Patienten liegt eine Einverständniserklärung vor.
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Gombert, A., Stoppe, C., Martin, L. et al. Stellenwert von prognostischen Biomarkern in der offenen und endovaskulären Aortenchirurgie. Gefässchirurgie 23, 529–532 (2018). https://doi.org/10.1007/s00772-018-0432-6
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DOI: https://doi.org/10.1007/s00772-018-0432-6