# Evaluation of the limit of performance of an analytical method based on a statistical calculation of its critical concentrations according to iso standard 11843: Application to routine control of banned veterinary drug residues in food according to European Decision 657/2002/EC

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**Accred Qual Assur (2006) 11(1–2):58–62**

The hereabove mentionned article published in the April 2006 Issue No 1–2 Page 58–62 of the Journal contains a parenthesis mistake in 2 formulas of its page 59. This mistake may lead to corruption in the calculations for the readers not familiar with ISO Standard 11843–2. In the part entitled **Concept of calculation of critical concentrations according to Standard ISO11843**, for the calculation of CCα and CCβ applied to what is called *MRL substances*,

it is recommended to use the following formulas where is added a set of parenthesis at the numerator of the 3rd term under the square root :

$$
{\it CC}\alpha = x_{\it MRL} + t_{(\alpha ,{\it IJ} - 2)} .\frac{{\hat \sigma }}{{\hat b}}.\sqrt {\frac{1}{K} + \frac{1}{{\it \it I.J}} + \frac{{(x_{\it MRL} - \bar x)^2}}{{\sum {(x_{ij} - \bar x} )^2}}}
$$

$$
{\it CC}\beta = x_{\it MRL} + \delta _{({\it I.J} - 2;\alpha ;\beta )} .\frac{{\hat \sigma }}{{\hat b}}.\sqrt {\frac{1}{K} + \frac{1}{{\it I.J}} + \frac{{(x_{\it MRL} - \bar x)^2}}{{\sum {(x_{ij} - \bar x} )^2}}}
$$

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