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Orale Mukositis bei Patienten unter Tumortherapie

Oral mucositis in patients undergoing tumor therapy

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Zusammenfassung

Zu den unerwünschten Nebenwirkungen bestimmter Chemo- und Radiotherapien gehört die orale Mukositis, eine Entzündung der Mundschleimhaut. Da sie die Lebensqualität der Patienten in hohem Maße beeinträchtigen kann, sollten Pflegende der Mundhygiene einen besonders hohen Stellenwert beimessen. In der täglichen Praxis wird die orale Mukositis oft kontrovers diskutiert. In diesem Artikel werden aktuelle theoriebasierte und erfahrungsbasierte Grundlagen und Anleitungen für die Pflege und Behandlung vorgestellt.

Abstract

Oral mucositis remains one of the possible side effects of some chemotherapy and radiotherapy regimens. The patients’ quality of life can be severely compromised. Nurses should attach great importance to this symptom. Discussions dealing with oral mucositis in daily practice are still often controversial. The current theory- and experience-based principles and recommendations for the management of oral mucositis are presented.

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Literatur

  1. National Cancer Institute, PDQ (2003) Oral complications of cancer and cancer therapy. Update (Webdokument)

  2. Köstler WJ et al. (2001) Oral mucositis complicating chemotherapy and/or radiotherapy CA Cancer. J Clinicians 51: 290–315

    Google Scholar 

  3. Wilkes J (1998) Prevention and Treatment of oral Mucositis Following Cancer Chemotherapy. Semin Oncol, 25: 538–551

    Google Scholar 

  4. Borbasi S et al. (2002 More than a sore Mouth: Patients Experience of Oral Mucositis. Oncol Nursing Forum 29: 1051–1057

    Google Scholar 

  5. Eilers J (2004) Nursing Interventions and Supportive Care for the Prevention and Treatment of Oral Mucositis Associated with Cancer Therpay. Oncol Nursing Forum 31 (Suppl) 13–23

    Google Scholar 

  6. Brown CG, Wiingard J (2004) Clinical Consequences of Oral Mucositis. Semin Oncol Nursing, 20, 1: 16–21

  7. Larson PJ et al. (1998) The PRO-SELF Mouth Aware program: An effective approach for reducing chemotherapy-induced mucositis. Cancer Nursing 21: 263–268

    Article  PubMed  Google Scholar 

  8. Sonis ST et al. (1999) Validation of a New Scoring System for the Assessment of Clinical Trial Research of Oral Mucositis Induced by Radiation or Chemotherapy. Cancer 85: 2103–2113

    Article  PubMed  Google Scholar 

  9. Eilers J, Epstein J (2004) Assessment and Measurement of Oral Mucositis. Semin Oncol Nursing 20: 22–29

    Article  Google Scholar 

  10. Kearney N, Miller M, 2002 WISECARE Program, Wisecare+, Nursing Practice Protocol for oral care. European Commission, Brüssel,

  11. Foote RL et al. (1994) Randomized Trial of a Chlorhexidine Mouthwash for Alleviation of Radiation-Induced Mucositis. J Clin Oncol 12: 2630–2633

    PubMed  Google Scholar 

  12. Sonis ST et al. (2004) Mucositis: Perspectives and Clinical Practice Guidelines Perspectives on cancer-therapy-induced mucosal injury. Cancer 100: 1995–2025

    Article  PubMed  Google Scholar 

  13. Rubinstein RL et al. (2004) Clinical Practice Guidelines for the Prevention and Treatment of Cancer Therapy-Induced Oral and Gastrointestinal Mucositis. Cancer 100: 2026–2046

    Article  PubMed  Google Scholar 

  14. Nieweg RMB (1997) Mundschleimhautveränderungen und Mundpflege bei Chemotherapie, Ullstein Mosby, Berlin

  15. Miller M, Kearney N (2001) Oral Care for Patients with Cancer: A Review of the Literature. Cancer Nursing 24: 241–254

    Article  PubMed  Google Scholar 

  16. Cascinu S et al. (1994) Oral cooling (cryotherapy), an effective treatment for the prevention of 5-fluorouracil-induced stomatitis. Eur J Cancer 30B: 234–236

    Google Scholar 

  17. Rocke LK et al. (1993) A randomised clinical trial of two different durations of oral cryotherapy for prevention of 5-fluorouracil-related stomatitis. Cancer 72: 2234–8

    Article  PubMed  Google Scholar 

  18. Gottschalck T, Dassen T, Zimmer S, (2004) Empfehlungen für eine Evidenz-basierte Mundpflege bei Patienten in Gesundheits- und Pflegeeinrichtungen. Pflege 17: 78–91

    Article  PubMed  Google Scholar 

  19. Miller M, Kearney N (2001) Oral Care for Patients with Cancer: A Review of the Literature. Cancer Nursing 24: 241–254

    Article  PubMed  Google Scholar 

  20. Gosselin TK (2004) Supportive Care for Patients Receiving Radiation Treatment. Oncol Support Care Quarterly 2: 6–15

    Google Scholar 

  21. Peerman A, Cella C, Glandon G et al. (2001) Mucositis in head and neck cancer: economic and quality-of-life outcomes. Journal of the National Cancer Institute Monographs 4: 45–51

    Google Scholar 

  22. Shih A (2002) Research Review of the Current Treatments for Radiation –Induced Oral Mucositis in Patients with Head and Neck Cancer. Oncol Nursing Forum 29: 1063–1068

    Google Scholar 

  23. von Bültzingslöwen I et al. (2006) Growth factors and cytokines in the prevention and treatment of oral and gastrointestinal mucositis. Support Care Cancer 14: 519–527

    Article  PubMed  Google Scholar 

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Correspondence to A. Margulies.

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Bestellung des ausführlichen Konzepts, des Leitfadens für die Praxis und den Qualitätsstandard: http://www.onkologiepflege.ch; E-Mail: info@onkologiepflege.ch

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Margulies, A., Bigler-Perrotin, L., Willems Cavalli, Y. et al. Orale Mukositis bei Patienten unter Tumortherapie. Onkologe 13, 350–355 (2007). https://doi.org/10.1007/s00761-006-1177-5

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  • DOI: https://doi.org/10.1007/s00761-006-1177-5

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