Literatur
Chung KY, Shia J, Kemeny NE et al. (2005) Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol 23:1803–1810
Cunningham D, Humblet Y, Siena S et al. (2004) Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 351:337–345
Lenz HJ, Mayer RJ, Gold PJ et al. (2004) Activity of cetuximab in patients with colorectal cancer refractory to both irinotecan and oxaliplatin. Proc Am Soc Clin Oncol 22:247S
Lynch TJ, Bell DW, Sordella R et al. (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350:2129–2139
Meropol NJ (2005) Epidermal growth factor receptor inhibitors in colorectal cancer: it’s time to get back on target. J Clin Oncol 23:1791–1793
Paez JG, Janne PA, Lee JC et al. (2004) EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 304:1497–1500
Saltz LB, Meropol NJ, Loehrer PJ Sr, Needle MN, Kopit J, Mayer RJ (2004) Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol 22:1201–1208
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Kretzschmar, A. Wirksamkeit von Cetuximab und Irinotecan beim metastasierten kolorektalen Karzinom — EGF-Rezeptor-negativ. Onkologe 11, 783–784 (2005). https://doi.org/10.1007/s00761-005-0902-9
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DOI: https://doi.org/10.1007/s00761-005-0902-9