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Thorakale Strahlentherapie

Zeitpunkt, Fraktionierung, Zielvolumendosis

Thoracic radiotherapy

Time, fractionation, dose

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Zusammenfassung

Beim kleinzelligen Lungenkarzinom muss die Dosisintensität der zytotoxischen Behandlungsmodalitäten als wichtige therapeutische Größe angesehen werden. Dies gilt sowohl für die Chemo- als auch die Strahlentherapie in ihrer Kobination. Die Mehrheit der verfügbaren Evidenz deutet an, dass der frühe Einsatz der thorakalen Strahlentherapie, simultan mit einer platinbasierten Zweitgenerationschemotherapie, einen moderaten therapeutischen Vorteil bei Patienten im UICC-Stadium I–III bietet.

Abstract

The dose intensity of cytotoxic modalities is of therapeutic relevance in patients with stage I–III small cell lung cancer. This applies to both systemic therapy and thoracic radiotherapy. The majority of published evidence suggests a therapeutic benefit for early radiotherapy given concurrently with second-generation platinum-based chemotherapy.

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Authors and Affiliations

  1. Klinik für Strahlentherapie, Innere Klinik und Poliklinik (Tumorforschung), Westdeutsches Tumorzentrum, Universitätsklinikum Essen

    C. Pöttgen, M. Stuschke & W. Eberhardt

  2. Klinik für Strahlentherapie, Innere Klinik und Poliklinik (Tumorforschung), Westdeutsches Tumorzentrum, Universitätsklinikum, Hufelandstraße 55, 45122, Essen

    C. Pöttgen

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  1. C. Pöttgen
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  2. M. Stuschke
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  3. W. Eberhardt
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Correspondence to C. Pöttgen.

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Pöttgen, C., Stuschke, M. & Eberhardt, W. Thorakale Strahlentherapie. Onkologe 11, 741–746 (2005). https://doi.org/10.1007/s00761-005-0885-6

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  • DOI: https://doi.org/10.1007/s00761-005-0885-6

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