Long-acting olanzapine injection during pregnancy and breastfeeding: a case report
We present one case of a woman treated with the intramuscular depot formulation of the atypical antipsychotic, olanzapine pamoate (ZypAdhera®), during pregnancy and breastfeeding. Data on olanzapine distribution in breast milk as well as on plasma concentration in the nursed infant are provided. The present case report demonstrates that olanzapine was excreted in the breast milk, but the breast-fed infant had very low olanzapine concentrations, which did not result in any adverse effects.
KeywordsOlanzapine Breastfeeding Pregnancy
The authors wish to thank head of Järva Psychiatric Out-patient Clinic, Dr. Kersti Gabrielsson, and head of the Psychosis Department at Järva Psychiatric Out-patient Clinic, Helena Persson, for support, and Camilla Rosales for assistance in data managing.
This study was funded by Praktikertjänst AB, Stockholm, Sweden (grant number FoU-2012).
Compliance with ethical standards
Conflict of interest
Irina Manouilenko, Inger Öhman and Jeanette Georgieva declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from the individual participant included in the study. Additional informed consent was obtained from the individual participant for whom identifying information is included in this article.
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