Skip to main content

Advertisement

SpringerLink
Log in

Biopsychosocial determinants of treatment outcome for mood and anxiety disorders up to 8 months postpartum

  • Short Communication
  • Published:
Archives of Women's Mental Health Aims and scope Submit manuscript

Abstract

Little is known about the biopsychosocial determinants that predict postpartum treatment outcome for mood and anxiety disorders. Postpartum mood and anxiety symptoms and psychosocial/biological variables were recorded for 8 months of 22 women treated with antidepressants during pregnancy. Depression scores decreased by 58 %, whereas anxiety scores decreased by 35 %. Family history of psychiatric illness and prior psychiatric illness unrelated to pregnancy predicted depressive treatment outcome, and sexual abuse history and prior psychiatric illness unrelated to pregnancy predicted anxiety outcome. Biological and psychosocial variables predicted pharmacological treatment outcome in postpartum-depressed and anxious women.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Beck CT (2001) Predictors of postpartum depression. Nurs Res 5:275–285

    Article  Google Scholar 

  • Benedict MI, Paine LL, Paine LA, Brandt D, Stallings R (1999) The association of childhood sexual abuse with depressive symptoms during pregnancy, and selected pregnancy outcomes. Child Abuse Negl 23:659–670

    Article  PubMed  CAS  Google Scholar 

  • Freeman MP, Wright R, Watchman M, Wahl RA, Sisk DJ, Fraleigh L, Weilbrecht JM (2005) Postpartum depression assessments at well-baby visits: screening feasibility, prevalence, and risk factors. J Womens Health (Larchmt) 14:929–935

    Article  Google Scholar 

  • Garabedian MJ, Lain KY, Hansen WF, Garcia LS, Williams CM, Crofford LJ (2011) Violence against women and postpartum depression. J Womens Health (Larchmt) 20:447–453

    Article  Google Scholar 

  • Hamilton M (1959) The assessment of anxiety states by rating. Br J Med Psychol 32:50–55

    Article  PubMed  CAS  Google Scholar 

  • Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56–62

    Article  PubMed  CAS  Google Scholar 

  • Lancaster CA, Gold KJ, Flynn HA, Yoo H, Marcus SM, Davis MM (2010) Risk factors for depressive symptoms during pregnancy: a systematic review. Am J Obstet Gynecol 202(1):5–14

    Article  PubMed  Google Scholar 

  • Misri S, Kendrick K, Oberlander TF, Norris S, Tomfohr L, Zhang H, Grunau RE (2010) Antenatal depression and anxiety affect postpartum parenting stress: a longitudinal, prospective study. Can J Psychiatry 55:222–228

    PubMed  Google Scholar 

  • O'Hara MW, Swain AM (1996) Rates and risk of postpartum depression—a meta-analysis. Int Rev Psychiatry 8:37–54

    Article  Google Scholar 

  • Ross LE, McLean LM (2006) Anxiety disorders during pregnancy and the postpartum period: a systematic review. J Clin Psychiatry 67:1285–1298

    Article  PubMed  Google Scholar 

  • Sichel D, Driscoll JW (1999) Women's moods. What every woman must know about hormones, the brain, and emotional health. William Morrow, New York

    Google Scholar 

  • Skouteris H, Wertheim EH, Rallis S, Milgrom J, Paxton SJ (2009) Depression and anxiety through pregnancy and the early postpartum: an examination of prospective relationships. J Affect Disord 113:303–308

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

The authors thank Hongbin Zhang and Dr. Mike Papsdorf for all of their statistical assistance and insight they contributed to the project. The authors would also like to thank Colleen Fitzgerald and Annie Kuan for data collection as well as Arjun Nanda. We are very grateful to all of the women who participated in this study. This work was supported by funding from the British Columbia Medical Services Foundation (grant no. BCM96-0152). Overall experimental design, data acquisition, statistical analyses, and interpretation of results were implemented without any input from this source. Ethics certificates were received from the University of British Columbia (C01-0312) and Providence Health Care (P01-0129). Dr. Shaila Misri has received Speaker's Bureau honoraria, served as a consultant for, and received research funding from Astra Zeneca, Lundbeck, and Pfizer in the last 12 months. Dr. Deirdre Ryan and Dr. Diana Carter are co-investigators with Dr. Shaila Misri on research projects which have received funding from Astra Zeneca, Lundbeck, and Pfizer. Dr. Deirdre Ryan has also received Speaker's Bureau honoraria from Astra Zeneca.

Conflict of interest

Dr. Oberlander, Ms. Abizadeh, Ms. Albert, and Ms. Kendrick report no competing interests.

Author information

Authors and Affiliations

  1. Reproductive Mental Health Program, St. Paul’s Hospital and B.C. Children’s and Women’s Hospital, Mental Health Building Room P1-228, 4500 Oak Street, Vancouver, BC, Canada, V6H 3N1

    Shaila Misri, Gillian Albert, Jasmin Abizadeh, Kristin Kendrick, Diana Carter & Deirdre Ryan

  2. Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada

    Shaila Misri, Gillian Albert, Jasmin Abizadeh, Diana Carter & Deirdre Ryan

  3. Department of Pediatrics, Biobehavioral Research Unit, Centre for Community Child Health Research, Research Institute for Children’s & Women’s Health, University of British Columbia, Vancouver, BC, Canada

    Tim F. Oberlander

Authors
  1. Shaila Misri
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Gillian Albert
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jasmin Abizadeh
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kristin Kendrick
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Diana Carter
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Deirdre Ryan
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Tim F. Oberlander
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Shaila Misri.

Additional information

The material in this manuscript represents original research findings and is not being considered for publication elsewhere.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Misri, S., Albert, G., Abizadeh, J. et al. Biopsychosocial determinants of treatment outcome for mood and anxiety disorders up to 8 months postpartum. Arch Womens Ment Health 15, 313–316 (2012). https://doi.org/10.1007/s00737-012-0288-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00737-012-0288-9

Keywords

Search

Navigation