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Amino Acids

, Volume 46, Issue 1, pp 31–46 | Cite as

Taurine and central nervous system disorders

  • Janet Menzie
  • Chunliu Pan
  • Howard PrenticeEmail author
  • Jang-Yen WuEmail author
Review Article

Abstract

In the present era, investigators seek to find therapeutic interventions that are multifaceted in their mode of action. Such targets provide the most advantageous routes for addressing the multiplicity of pathophysiological avenues that lead to neuronal dysfunction and death observed in neurological disorders and neurodegenerative diseases. Taurine, an endogenous amino acid, exhibits a plethora of physiological functions in the central nervous system. In this review, we describe the mode of action of taurine and its clinical application in the neurological diseases: Alzheimer’s disease, Parkinson’s disease and Huntington’s disease.

Keywords

Taurine Neuroprotective mechanisms Alzheimer’s disease Parkinson’s disease Huntington’s disease 

Notes

Acknowledgments

This work was supported, in part, by the James and Esther King Biomedical Research Program, Florida Department of Health (grant #: 09KW-11), and the Schmidt Foundation, Charles E. Schmidt College of Medicine, Florida Atlantic University.

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Authors and Affiliations

  1. 1.Program in Integrative BiologyFlorida Atlantic UniversityBoca RatonUSA
  2. 2.Department of Biomedical SciencesFlorida Atlantic UniversityBoca RatonUSA
  3. 3.Department of Chemistry and BiochemistryFlorida Atlantic UniversityBoca RatonUSA

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