Skip to main content

Latest news about the sulfurtransferase protein family of higher plants

Amino Acids volume 41, pages 43–57 (2011)Cite this article

Abstract

Sulfurtransferases/rhodaneses (Str) comprise a group of enzymes widely distributed in all phyla which catalyze in vitro the transfer of a sulfur atom from suitable sulfur donors to nucleophilic sulfur acceptors. The best characterized Str is bovine rhodanese (EC 2.8.1.1) which catalyses in vitro the transfer of a sulfane sulfur atom from thiosulfate to cyanide, leading to the formation of sulfite and thiocyanate. Plants as well as other organisms contain many proteins carrying a typical rhodanese pattern or domain forming multi-protein families (MPF). Despite the presence of Str activities in many living organisms, the physiological role of the members of this MPF has not been established unambiguously. While in mammals these proteins are involved in the elimination of toxic cyanogenic compounds, their ubiquity suggests additional physiological functions. In plants, Str are localized in the cytoplasm, mitochondria, plastids, and nucleus. Str probably also transfer reduced sulfur onto substrates as large as peptides or proteins. Several studies in different organisms demonstrate a protein–protein interaction with members of the thioredoxin MPF indicating a role of Str in maintenance of the cellular redox homeostasis. The increased expression of several members of the Str MPF in various stress conditions could be a response to oxidative stress. In summary, data indicate that Str are involved in various essential metabolic reactions.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

39,95 €

Price includes VAT (Finland)

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Abbreviations

Acc. no.:

Accession number

AR:

Arsenate reductase

CAS:

β-Cyano-l-alanine synthase

Cys:

Cysteine

E. coli :

Escherichia coli

3-MP:

3-Mercaptopyruvate

3-MP Str:

3-Mercaptopyruvate Str

Str:

Sulfurtransferase(s)

TS:

Thiosulfate

TS Str:

Thiosulfate sulfurtransferase

References

  • Abeles FB, Morgan PW, Saltveit ME (1992) Ethylene biosynthesis in plant biology. Academic Press, San Diego

    Google Scholar 

  • Adams H, Teertstra W, Koster M, Tommassen J (2002) PspE (phage-shock protein E) of Escherichia coli is a rhodanese. FEBS Lett 518:173–176

    Article  PubMed  CAS  Google Scholar 

  • Alphey MS, Williams RA, Mottram JC, Coombs GH, Hunter WN (2003) The crystal structure of Leishmania major 3-mercaptopyruvate sulfurtransferase. A three-domain architecture with a serine protease-like triad at the active site. J Biol Chem 278:48219–48227

    Article  PubMed  CAS  Google Scholar 

  • Azumi Y, Watanabe A (1991) Evidence for a senescence associated gene induced by darkness. Plant Physiol 95:577–583

    Article  PubMed  CAS  Google Scholar 

  • Balmer Y, Vensel WH, Tanaka CK, Hurkman WJ, Gelhaye E, Rouhier N, Jacquot JP, Manieri W, Schürmann P, Droux M, Buchanan BB (2004) Thioredoxin links redox to the regulation of fundamental processes of plant mitochondria. Proc Natl Acad Sci USA 101:2642–2647

    Article  PubMed  CAS  Google Scholar 

  • Bartels A (2006) Functional characterisation of sulfurtransferase proteins in higher plants. PhD thesis, Leibniz Universität Hannover

  • Bartels A, Forlani F, Pagani S, Papenbrock J (2007a) Conformational studies on Arabidopsis sulfurtransferase AtStr1 analysed by spectroscopic methods. Biol Chem 388:53–59

    Article  PubMed  CAS  Google Scholar 

  • Bartels A, Mock HP, Papenbrock J (2007b) Differential expression of Arabidopsis sulfurtransferases under various growth conditions. Plant Physiol Biochem 45:178–187

    Article  PubMed  CAS  Google Scholar 

  • Bauer M, Papenbrock J (2002) Identification and characterization of single-domain thiosulfate sulfurtransferases from Arabidopsis thaliana. FEBS Lett 532:427–431

    Article  PubMed  CAS  Google Scholar 

  • Bauer M, Dietrich C, Nowak K, Sierralta WD, Papenbrock J (2004) Intracellular localization of sulfurtransferases from Arabidopsis thaliana. Plant Physiol 135:916–926

    Article  PubMed  CAS  Google Scholar 

  • Blumenthal S, Hendrickson H, Abrol Y, Conn E (1968) Cyanide metabolism in higher plants: III. The biosynthesis of β-cyanoalanine. J Biol Chem 243:5302–5307

    PubMed  CAS  Google Scholar 

  • Bonomi F, Pagani S, Cerletti P, Cannella C (1977) Rhodanese-mediated sulfur transfer to succinate dehydrogenase. Eur J Biochem 72:17–24

    Article  PubMed  CAS  Google Scholar 

  • Bordo D, Bork P (2002) The rhodanese/Cdc25 phosphatase superfamily. Sequence-structure-function relations. EMBO Rep 3:741–746

    Article  PubMed  CAS  Google Scholar 

  • Bordo D, Deriu D, Colnaghi R, Carpen A, Pagani S, Bolognesi M (2000) The crystal structure of a sulfurtransferase from Azotobacter vinelandii highlights the evolutionary relationship between the rhodanese and phosphatase enzyme families. J Mol Biol 298:691–704

    Article  PubMed  CAS  Google Scholar 

  • Bracha-Drori K, Shichrur K, Katz A, Oliva M, Angelovici R, Yalovsky S, Ohad N (2004) Detection of protein–protein interactions in plants using bimolecular fluorescence complementation. Plant J 40:419–427

    Article  PubMed  CAS  Google Scholar 

  • Burow M, Kessler D, Papenbrock J (2002) Enzymatic activity of the Arabidopsis sulfurtransferase resides in the C-terminal domain but is boosted by the N-terminal domain and the linker peptide in the full-length enzyme. Biol Chem 383:1363–1372

    Article  PubMed  CAS  Google Scholar 

  • Cannella C, Berni R, Ricci G (1984) Determination of rhodanese activity by tetrazolium reduction. Anal Biochem 142:159–162

    Article  PubMed  CAS  Google Scholar 

  • Chew NY (1973) Rhodanese in higher plants. Phytochemistry 12:2365–2367

    Article  CAS  Google Scholar 

  • Chung B-C, Lee SY, Oh SA, Rhew TH, Nam HG, Lee C-H (1997) The promoter activity of sen1, a senescence-associated gene of Arabidopsis, is repressed by sugars. J Plant Physiol 151:339–345

    CAS  Google Scholar 

  • Colnaghi R, Cassinelli G, Drummond M, Forlani F, Pagani S (2001) Properties of the Escherichia coli rhodanese-like protein SseA: contribution of the active-site residue Ser240 to sulfur donor recognition. FEBS Lett 500:153–156

    Article  PubMed  CAS  Google Scholar 

  • Cooper RM, Williams JS (2004) Elemental sulphur as an induced antifungal substance in plant defence. J Exp Bot 55:1947–1953

    Article  PubMed  CAS  Google Scholar 

  • Cooper RM, Resende ML, Flood J, Rowan MG, Beale MH, Potter U (1996) Detection and cellular localization of elemental sulphur in disease-resistant genotypes of Theobroma cacao. Nature 379:159–162

    Article  CAS  Google Scholar 

  • Cornilescu G, Vinarov DV, Tyler EM, Merkley JL, Cornilescu CC (2006) Solution structure of a single-domain from Arabidopsis thaliana. Protein Sci 15:2836–2841

    Article  PubMed  CAS  Google Scholar 

  • Donadio S, Shafiee A, Hutchinson R (1990) Disruption of a rhodanese like gene results in cysteine auxotrophy in Saccharopolyspora erythraea. J Bacteriol 172:350–360

    PubMed  CAS  Google Scholar 

  • Duan GL, Zhu YG, Tong YP, Cai C, Kneer R (2005) Characterization of arsenate reductase in the extract of roots and fronds of Chinese brake fern, an arsenic hyperaccumulator. Plant Physiol 138:461–469

    Article  PubMed  CAS  Google Scholar 

  • Dubuis P-H, Marazzi C, Staedler E, Mauch F (2005) Sulphur deficiency causes a reduction in antimicrobial potential and leads to increased disease susceptibility of oilseed rape. J Phytopathol 153:27–36

    Article  CAS  Google Scholar 

  • Gemeinhardt K (1938) The thiocyanate content of plants. Ber Deut Botan Ges 56:275

    CAS  Google Scholar 

  • Glatz Z, Bouchal P, Janiczek O, Mandl M, Ceskova P (1999) Determination of rhodanese enzyme activity by capillary zone electrophoresis. J Chromat A 838:139–148

    Article  CAS  Google Scholar 

  • Gliubich F, Gazerro M, Canotti G, Delbono S, Bombieri G, Berni R (1996) Active site structural features for chemically modified forms of rhodanese. J Biol Chem 271:21054–21061

    Article  PubMed  CAS  Google Scholar 

  • Hama H, Kayahara T, Ogawa W, Tsuda M, Tsuchiya T (1994) Enhancement of serine-sensitivity by a gene encoding rhodanese-like protein in Escherichia coli. J Biochem 115:1135–1140

    PubMed  CAS  Google Scholar 

  • Hatzfeld Y, Saito K (2000) Evidence for the existence of rhodanese (thiosulfate:cyanide sulfurtransferase) in plants: preliminary characterization of two rhodanese cDNAs from Arabidopsis thaliana. FEBS Lett 470:147–150

    Article  PubMed  CAS  Google Scholar 

  • Heazlewood JL, Tonti-Filippini JS, Gout AM, Day DA, Whelan J, Millar AH (2004) Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Plant Cell 16:241–256

    Article  PubMed  CAS  Google Scholar 

  • Hildebrandt TM, Grieshaber MK (2008) Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria. FEBS J 275:3352–3361

    Article  PubMed  CAS  Google Scholar 

  • Huang J, Niknahad H, Khan S, O’Brien PJ (1998) Hepatocyte-catalysed detoxification of cyanide by L-and D-cysteine. Biochem Pharmacol 55:1983–1990

    Article  PubMed  CAS  Google Scholar 

  • Jarabak R, Westley J (1978) Steady-state kinetics of 3-mercaptopyruvate sulfurtransferase from bovine kidney Arch. Biochem Biophys 185:458–465

    Article  CAS  Google Scholar 

  • Kakes P, Hakvoort H (1992) Is there rhodanese activity in plants? Phytochemistry 31:1501–1505

    Article  CAS  Google Scholar 

  • Kende H (1993) Ethylene biosynthesis. Ann Rev Plant Physiol Plant Mol Biol 44:283–307

    Article  CAS  Google Scholar 

  • Klimmek O, Stein T, Pisa R, Simon J, Kroger A (1999) The single cysteine residue of the Sud protein is required for its function as a polysulfide-sulfur transferase in Wolinella succinogenes. Eur J Biochem 263:79–84

    Article  PubMed  CAS  Google Scholar 

  • Laloi C, Rayapuram N, Chartier Y, Grienenberger JM, Bonnard G, Meyer Y (2001) Identification and characterization of a mitochondrial thioredoxin system in plants. Proc Natl Acad Sci USA 98:14144–14149

    Article  PubMed  CAS  Google Scholar 

  • Landrieu I, da Costa M, De Veylder L, Dewitte F, Vandepoele K, Hassan S, Wieruszeski JM, Corellou F, Faure JD, Van Montagu M, Inzé D, Lippens G (2004) A small CDC25 dual-specificity tyrosine-phosphatase isoform in Arabidopsis thaliana. Proc Natl Acad Sci USA 101:13380–13385

    Article  PubMed  CAS  Google Scholar 

  • Laudenbach DE, Ehrhardt D, Green L, Grossmann A (1991) Isolation and characterization of a sulfur-regulated gene encoding a periplasmatically localized protein with sequence similarity to rhodanese. J Bacteriol 173:2751–2760

    PubMed  CAS  Google Scholar 

  • Leimkuehler S, Rajagopalan KV (2001) A sulfurtransferase is required in the transfer of cysteine sulfur in the in vitro synthesis of molybdopterin from precursor Z in Escherichia coli. J Biol Chem 276:22024–22031

    Article  Google Scholar 

  • Louie M, Kondor N, DeWitt JG (2003) Gene expression in cadmium-tolerant Datura innoxia: detection and characterization of cDNAs induced in response to Cd2+. Plant Mol Biol 52:81–89

    Article  PubMed  CAS  Google Scholar 

  • Luo GX, Horowitz PM (1994) The sulfurtransferase activity and structure of rhodanese are affected by site-directed replacement of Arg-186 or Lys-249. J Biol Chem 269:8220–8225

    PubMed  CAS  Google Scholar 

  • Manning K (1988) Detoxification of cyanide by plants and hormone action. Ciba Found Symp 140:92–110

    PubMed  CAS  Google Scholar 

  • Marchand C, Le Marechal P, Meyer Y, Decottignies P (2006) Comparative proteomic approaches for the isolation of proteins interacting with thioredoxin. Proteomics 6:6528–6537

    Article  PubMed  CAS  Google Scholar 

  • Matthies A, Rajagopalan KV, Mendel RR, Leimkuehler S (2004) Evidence for the physiological role of a rhodanese-like protein for the biosynthesis of the molybdenum cofactor in humans. Proc Natl Acad Sci USA 101:5946–5951

    Article  PubMed  CAS  Google Scholar 

  • Melino S, Cicero DO, Orsale M, Forlani F, Pagani S, Paci M (2003) Azotobacter vinelandii rhodanese: selenium loading and ion interaction studies. Eur J Biochem 270:4208–4215

    Article  PubMed  CAS  Google Scholar 

  • Mendel RR (2007) Biology of the molybdenum cofactor. J Exp Bot 58:2289–2296

    Article  PubMed  CAS  Google Scholar 

  • Meyer T, Burow M, Bauer M, Papenbrock J (2003) Arabidopsis sulfurtransferases: investigation of their function during senescence and in cyanide detoxification. Planta 217:1–10

    PubMed  CAS  Google Scholar 

  • Meyer Y, Reichheld JP, Vignols F (2005) Thioredoxins in Arabidopsis and other plants. Photosynth Res 86:419–433

    Article  PubMed  CAS  Google Scholar 

  • Misson J, Raghothama KG, Jain A, Jouhet J, Block MA, Bligny R, Ortet P, Creff A, Somerville S, Rolland N, Doumas P, Nacry P, Herrerra-Estrella L, Nussaume L, Thibaud MC (2005) A genome-wide transcriptional analysis using Arabidopsis thaliana affymetrix gene chips determined plant responses to phosphate deprivation. Proc Natl Acad Sci USA 102:11934–11939

    Article  PubMed  CAS  Google Scholar 

  • Nagahara N (2007) Molecular evolution of thioredoxin-dependent redox-sensing switch in mercaptopyruvate sulfurtransferase. Res Adv Biol Chem 1:19–26

    Google Scholar 

  • Nagahara N, Katayama A (2005) Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis. J Biol Chem 280:34569–34776

    Article  PubMed  CAS  Google Scholar 

  • Nagahara N, Nishino T (1996) Role of amino acid residues in the active site of rat liver mercaptopyruvate sulfurtransferase. cDNA cloning, overexpression, and site-directed mutagenesis. J Biol Chem 271:27395–27401

    Article  PubMed  CAS  Google Scholar 

  • Nagahara N, Okazaki T, Nishino T (1995) Cytosolic mercaptopyruvate sulfurtransferase is evolutionary related to mitochondrial rhodanese. J Biol Chem 270:16230–16235

    Article  PubMed  CAS  Google Scholar 

  • Nagahara N, Ito T, Kitamura H, Nishino T (1998) Tissue and subcellular distribution of mercaptopyruvate sulfurtransferase in the rat: confocal laser fluorescence and immunoelectron microscopic studies combined with biochemical analysis. Histochem Cell Biol 110:243–250

    Article  PubMed  CAS  Google Scholar 

  • Nagahara N, Ito T, Minami M (1999) Mercaptopyruvate sulfurtransferase as a defense against cyanide toxication: Molecular properties and mode of detoxification. Histol Histopathol 14:1277–1286

    PubMed  CAS  Google Scholar 

  • Nagahara N, Yoshii T, Abe Y, Matsumura T (2007) Thioredoxin-dependent enzymatic activation of mercaptopyruvate sulfurtransferase. An intersubunit disulfide bond serves as a redox switch for activation. J Biol Chem 282:1561–1569

    Article  PubMed  CAS  Google Scholar 

  • Nakamura T, Yamaguchi Y, Sano H (2000) Plant mercaptopyruvate sulfurtransferases: molecular cloning, subcellular localization and enzymatic activities. Eur J Biochem 267:5621–5630

    Article  PubMed  CAS  Google Scholar 

  • Nandi DL, Horowitz PM, Westley J (2000) Rhodanese as a thioredoxin oxidase. Int J Biochem Cell Biol 32:465–473

    Article  PubMed  CAS  Google Scholar 

  • Niu JS, Yu L, Ma Z-Q, Chen P-D, Liu D-J (2002) Molecular cloning, characterization and mapping of a rhodanese like gene in wheat. Acta Genet Sin 29:266–272

    PubMed  CAS  Google Scholar 

  • Ogasawara Y, Lacourciere G, Stadtman T (2001) Formation of a selenium-substituted rhodanese by reaction with selenite and glutathione: possible role of a protein perselenide in a selenium delivery system. Proc Natl Acad Sci USA 98:9494–9498

    Article  PubMed  CAS  Google Scholar 

  • Oh SA, Lee SY, Chung IK, Lee CH, Nam HG (1996) A senescence-associated gene of Arabidopsis thaliana is distinctively regulated during natural and artificially induced leaf senescence. Plant Mol Biol 30:739–754

    Article  PubMed  CAS  Google Scholar 

  • Okolie PN, Obasi BN (1993) Diurnal variation of cyanogenic glucosides, thiocyanate and rhodanese in cassava. Phytochemistry 33:775–778

    Article  CAS  Google Scholar 

  • Okubara PA, Berry PM (1999) A mRNA (Accession No. AF109156) from symbiotic root nodules of Datisca glomerata with homology to thiosulfate sulfurtransferase genes. PGR 99–027. Plant Physiol 119:1147

    Article  Google Scholar 

  • Pagani S, Bonomi F, Cerletti P (1984) Enzymic synthesis of the iron-sulfur cluster of spinach ferredoxin. Eur J Biochem 142:361–366

    Article  PubMed  CAS  Google Scholar 

  • Pagani S, Eldridge M, Eady RR (1987) Nitrogenase of Klebsiella pneumoniae: rhodanese-catalyzed restoration of activity of inactive 2Fe species of the Fe protein. Biochem J 244:485–488

    PubMed  CAS  Google Scholar 

  • Palenchar PM, Buck CJ, Cheng H, Larson TJ, Mueller EG (2000) Evidence that thiI, an enzyme shared between thiamine and 4-thiouridine biosynthesis, may be a sulfurtransferase that proceeds through a persulfide intermediate. J Biol Chem 275:8283–8286

    Article  PubMed  CAS  Google Scholar 

  • Pantoja-Uceda D, López-Méndez B, Koshiba S, Inoue M, Rigawa T, Terada T, Shirouzu M, Tanaka A, Seki M, Shinozaki K, Yokoyama S, Güntert P (2005) Solution structure of the rhodanese homology domain At4g01050 (175–295) from Arabidopsis thaliana. Protein Sci 14:224–230

    Article  PubMed  CAS  Google Scholar 

  • Papenbrock J, Grimm B (2001) Regulatory network of tetrapyrrole biosynthesis—studies of intracellular signalling involved in metabolic and developmental control of plastids. Planta 213:667–681

    Article  PubMed  CAS  Google Scholar 

  • Papenbrock J, Schmidt A (2000a) Characterization of a sulfurtransferase from Arabidopsis thaliana. Eur J Biochem 267:145–154

    Article  PubMed  CAS  Google Scholar 

  • Papenbrock J, Schmidt A (2000b) Characterization of two sulfurtransferase isozymes from Arabidopsis thaliana. Eur J Biochem 267:5571–5579

    Article  PubMed  CAS  Google Scholar 

  • Papenbrock J, Bartels A, Hartmann F, Hartmann J, Triulzi T (2009) Reduced sulfur in the plant cell–enzymatic formation and functional roles. In: Sirko A et al (eds) Sulfur metabolism in higher plants. Backhuys Publishers, Leiden, pp 217–219

    Google Scholar 

  • Peltier JB, Ytterberg AJ, Sun Q, van Wijk KJ (2004) New functions of the thylakoid membrane proteome of Arabidopsis thaliana revealed by a simple, fast, and versatile fractionation strategy. J Biol Chem 279:49367–49383

    Article  PubMed  CAS  Google Scholar 

  • Piotrowski M, Schönfelder S, Weiler EW (2001) The Arabidopsis thaliana isogene NIT4 and its orthologs in tobacco encode β-cyano-l-alanine hydratase/nitrilase. J Biol Chem 276:2616–2621

    Article  PubMed  CAS  Google Scholar 

  • Ploegman JH, Drent G, Kalk KH, Hol WGJ, Heinrikson RL, Keim P, Weng L, Russell J (1978) The covalent and tertiary structure of bovine liver rhodanese. Nature 273:124–129

    Article  PubMed  CAS  Google Scholar 

  • Prieto JL, Perez-Castineira JR, Vega JM (1997) Thiosulfate reductase from Chlamydomonas. J Plant Physiol 151:385–389

    CAS  Google Scholar 

  • Rajjou L, Lovigny Y, Groot SP, Belghazi M, Job C, Job D (2008) Proteome-wide characterization of seed aging in Arabidopsis: a comparison between artificial and natural aging protocols. Plant Physiol 148:620–641

    Article  PubMed  CAS  Google Scholar 

  • Rausch T, Wachter A (2005) Sulfur metabolism: a versatile platform for launching defence operations. Trends Plant Sci 10:503–509

    Article  PubMed  CAS  Google Scholar 

  • Ray WK, Zeng G, Potters MB, Mansuri AM, Larson TJ (2000) Characterization of a 12-kilodalton rhodanese encoded by glpE of Escherichia coli and its interaction with thioredoxin. J Bacteriol 182:2277–2284

    Article  PubMed  CAS  Google Scholar 

  • Russell J, Weng L, Keim PS, Heinrikson RL (1978) The covalent structure of bovine liver rhodanese. J Biol Chem 253:8102–8108

    PubMed  CAS  Google Scholar 

  • Sabelli R, Iorio E, De Martino A, Podo F, Ricci A, Viticchiè G, Rotilio G, Paci M, Melino S (2008) Rhodanese-thioredoxin system and allyl sulfur compounds. FEBS J 275:3884–3899

    Article  PubMed  CAS  Google Scholar 

  • Schenk PM, Kazan K, Rusu AG, Manners JM, Maclean DJ (2005) The SEN1 gene of Arabidopsis is regulated by signals that link plant defence responses and senescence. Plant Physiol Biochem 43:997–1005

    Article  PubMed  CAS  Google Scholar 

  • Schievelbein H, Baumeister R, Vogel R (1969) Comparative investigations on the activity of thiosulphate-sulphur transferase. Naturwissenschaften 56:416–417

    Article  PubMed  CAS  Google Scholar 

  • Schmidt A (1984) Occurrence of mercaptopyruvate sulfotransferase activity in photosynthetic organisms. Z Naturforsch 39c:916–921

    CAS  Google Scholar 

  • Schmidt A, Erdle I, Gamon B (1984) Isolation and characterization of thiosulfate reductases from the green alga Chlorella fusca. Planta 162:243–249

    Article  CAS  Google Scholar 

  • Shimada Y, Wu GJ, Watanabe A (1998) A protein encoded by din1, a dark-inducible and senescence-associated gene of radish, can be imported by isolated chloroplasts and has sequence similarity to sulphide dehydrogenase and other small stress proteins. Plant Cell Physiol 39:139–143

    PubMed  CAS  Google Scholar 

  • Sörbo BH (1955) Rhodanese. Methods Enzymol 2:334–337

    Article  Google Scholar 

  • Spallarossa A, Donahue JL, Larson TJ, Bolognesi M, Bordo D (2001) Escherichia coli GlpE is a prototype sulfurtransferase for the single-domain rhodanese homology superfamily. Structure 9:1117–1125

    Article  PubMed  CAS  Google Scholar 

  • Spallarossa A, Forlani F, Carpen A, Armirotti A, Pagani S, Bolognesi M, Bordo D (2004) The “rhodanese” fold and catalytic mechanism of 3-mercaptopyruvate sulfurtransferases: crystal structure of SseA from Escherichia coli. J Mol Biol 335:583–593

    Article  PubMed  CAS  Google Scholar 

  • Toohey JI (1989) Sulphane sulphur in biological systems: a possible regulatory role. Biochem J 264:625–632

    PubMed  CAS  Google Scholar 

  • Vennesland B, Castric PA, Conn EE, Solomonson LP, Volini M, Westley J (1982) Cyanide metabolism. Fed Proc 41:2639–2648

    PubMed  CAS  Google Scholar 

  • Walter M, Chaban C, Schutze K, Batistic O, Weckermann K, Nake C, Blazevic D, Grefen C, Schumacher K, Oecking C, Harter K, Kudla J (2004) Visualization of protein interactions in living plant cells using bimolecular fluorescence complementation. Plant J 40:428–438

    Article  PubMed  CAS  Google Scholar 

  • Waltner M, Weiner H (1995) Conversion of a nonprocessed mitochondrial precursor protein into one that is processed by the mitochondrial processing peptidase. J Biol Chem 270:26311–26317

    Article  PubMed  CAS  Google Scholar 

  • Walz C, Giavalisco P, Schad M, Juenger M, Klose J, Kehr J (2004) Proteomics of curcurbit phloem exudate reveals a network of defence proteins. Phytochemistry 65:1795–1804

    Article  PubMed  CAS  Google Scholar 

  • Weaver LM, Gan S, Quirino B, Amasino RM (1998) A comparison of the expression patterns of several senescence-associated genes in response to stress and hormone treatment. Plant Mol Biol 37:455–469

    Article  PubMed  CAS  Google Scholar 

  • Westley J (1973) Rhodanese. Adv Enzymol 39:327–368

    PubMed  CAS  Google Scholar 

  • Westley J (1981) Thiosulfate:cyanide sulfurtransferase (rhodanese). Methods Enzymol 77:285–291

    Article  PubMed  CAS  Google Scholar 

  • Westley J, Heyse D (1971) Mechanisms of sulfur transfer catalysis sulfhydryl-catalyzed transfer of thiosulfonate sulfur. J Biol Chem 246:1468–1474

    PubMed  CAS  Google Scholar 

  • White RH (1982) Metabolism of l-[sulfane-34S]thiocystine by Escherichia coli. Biochemistry 21:4271–4275

    Article  PubMed  CAS  Google Scholar 

  • Williams JS, Cooper RM (2004) The oldest fungicide and newest phytoalexin–a reappraisal of the fungitoxicity of elemental sulphur. Plant Pathol 53:263–279

    Article  CAS  Google Scholar 

  • Williams JS, Hall SA, Hawkesford MJ, Beale MH, Cooper RM (2002) Elemental sulfur and thiol accumulation in tomato and defense against a fungal vascular pathogen. Plant Physiol 128:150–159

    Article  PubMed  CAS  Google Scholar 

  • Williams RA, Kelly SM, Mottram JC, Coombs GH (2003) 3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism. J Biol Chem 278:1480–1486

    Article  PubMed  CAS  Google Scholar 

  • Wood JL (1987) Sulfane sulfur. Methods Enzymol 143:25–29

    Article  PubMed  CAS  Google Scholar 

  • Wróbel M, Lewandowska I, Bronowicka-Adamska P, Paszewski A (2009) The level of sulfane sulfur in the fungus Aspergillus nidulans wild type and mutant strains. Amino Acids 37:565–571

    Article  PubMed  CAS  Google Scholar 

  • Yang SH, Berberich T, Miyazaki A, Sano H, Kusano T (2003) Ntdin, a tobacco senescence-associated gene, is involved in molybdenum cofactor biosynthesis. Plant Cell Physiol 44:1037–1044

    Article  PubMed  CAS  Google Scholar 

  • Zhao Y, Dai X, Blackwell HE, Schreiber SL, Chory J (2003) SIR1, an upstream component in auxin signaling identified by chemical genetics. Science 301:1107–1110

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

We would like to thank Dr. Fabio Forlani, Milan, Italy, for stimulating discussions. The work was financially supported by the Deutsche Forschungsgemeinschaft (PA 764/1-4 and 5, PA 764/7-1) and by the DAAD (Vigoni 0815171).

Author information

Authors and Affiliations

  1. Institute for Botany, Leibniz University Hannover, Herrenhäuserstr. 2, 30419, Hannover, Germany

    Jutta Papenbrock, Sebastian Guretzki & Melina Henne

Authors
  1. Jutta Papenbrock
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sebastian Guretzki
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Melina Henne
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jutta Papenbrock.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Papenbrock, J., Guretzki, S. & Henne, M. Latest news about the sulfurtransferase protein family of higher plants. Amino Acids 41, 43–57 (2011). https://doi.org/10.1007/s00726-010-0478-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00726-010-0478-6

Keywords

  • Arabidopsis thaliana
  • 3-Mercaptopyruvate
  • Oxidative stress
  • Thioredoxin
  • Thiosulfate