Amino Acids

, Volume 37, Issue 1, pp 105–110 | Cite as

Amino acids and gut function

  • W. W. Wang
  • S. Y. Qiao
  • D. F. LiEmail author
Review Article


The intestine is not only critical for the absorption of nutrients, but also interacts with a complex external milieu. Most foreign antigens enter the body through the digestive tract. Dietary amino acids are major fuels for the small intestinal mucosa, as well as important substrates for syntheses of intestinal proteins, nitric oxide, polyamines, and other products with enormous biological importance. Recent studies support potential therapeutic roles for specific amino acids (including glutamine, glutamate, arginine, glycine, lysine, threonine, and sulfur-containing amino acids) in gut-related diseases. Results of these new lines of work indicate trophic and cytoprotective effects of amino acids on gut integrity, growth, and health in animals and humans.


Amino acids Gut Intestinal mucosa Metabolism Inflammation 



Constitutive nitric oxide synthase


Inducible nitric oxide synthase


Nitric oxide


Nitric oxide synthase


Total parenteral nutrition



The authors are grateful to the National Natural Science Foundation of China for supporting our research.


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  1. 1.State Key Laboratory of Animal Nutrition, Ministry of Agriculture Feed Industry CentreChina Agricultural UniversityBeijingChina

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