Summary.
New γ-amino esters and amides were prepared by a radical 1,4-addition of carbon radicals to acrylic derivatives. α-Amino acids derivatives holding chiral auxiliaries as radical precursors and different chiral olefins were used and chiral induction on the C-γ center was discussed.
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Corvo, M., Pereira, M. Synthesis of γ-amino acid analogues from natural α-amino acids by a radical pathway. Amino Acids 32, 243–246 (2007). https://doi.org/10.1007/s00726-006-0378-y
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DOI: https://doi.org/10.1007/s00726-006-0378-y