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A review of approaches to the analysis of 3-nitrotyrosine

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Summary.

Our understanding of in vivo tyrosine nitration has been confounded by problems associated with the analytical approaches that have been employed to quantify 3-nitroyrosine (3-NT). Trace analysis is a demanding task under the best of circumstances, but 3-NT offers some special concerns. This review examines some of these concerns and discusses approaches to ensuring that carefully validated analytical data are generated.

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Authors and Affiliations

  1. Biochemical Mass Spectrometry, University of Colorado Health Sciences Center, Denver, Colorado, U.S.A., US

    M. W. Duncan

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  1. M. W. Duncan
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Duncan, M. A review of approaches to the analysis of 3-nitrotyrosine. Amino Acids 25, 351–361 (2003). https://doi.org/10.1007/s00726-003-0022-z

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  • DOI: https://doi.org/10.1007/s00726-003-0022-z

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