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Magnetic Resonance Diffusion Tensor Imaging in Evaluating Transcranial Magnetic Stimulation Treatment for Acute Ischemic Stroke: A Retrospective Study

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Abstract

Currently there is little report about the application of diffusion tensor imaging (DTI) technology to judge the prognosis of patients with cerebral apoplexy. This study was to investigate cerebral functional connection in both sides of the M1 area in patients with cerebral infarction, who were treated with transcranial magnetic stimulation (TMS), using DTI technology. Fifteen patients with cerebral infarction admitted to the hospital between February 2013 and August 2014 were enrolled for the study. The patients were treated with TMS and underwent DTI. The fractional anisotropy (FA), apparent diffusion coefficient (ADC), the relative FA value (rFA), and relative ADC values (rADC) were analyzed using paired t-test. rFA, rADC, and NIHSS of the lesion side before and after treatment were analyzed by Spearman correlation analysis. The results showed that before treatment, ADC value and FA value of the lesion side were lower than those of the contralateral healthy side with statistical significance (ADCt = 2.849, P < 0.05; FAt = 10.285, P < 0.05). Four weeks after treatment, ADC value and FA value of the lesion side were higher than those before treatment with statistical significance (ADCt = 6.206, P < 0.05; FAt = 3.788, P < 0.05). Both rFA values of pre-treatment and post-treatment showed negative correlation with NIHSS score with statistical significance (P < 0.05). In conclusion, after TMS with TDI technique, the value of FA and ADC values significantly increased compared to that of pre-treatment. It suggested that transcranial magnetic stimulation played a positive role in stroke rehabilitation.

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References

  1. S. Grupke, J. Hall, M. Dobbs, G.J. Bix, J.F. Fraser, Clin. Neurol. Neurosurg. 129, 1–9 (2015)

    Article  Google Scholar 

  2. J.A. Brown, Prog. Brain Res. 157, 223–228 (2006)

    Article  Google Scholar 

  3. J.V. Escudero, J. Sancho, D. Bautista, M. Escudero, J. López-Trigo, Stroke 29, 1854–1859 (1998)

    Article  Google Scholar 

  4. D. Salat, D. Tuch, D. Greve, A. Van Der Kouwe, N. Hevelone, A. Zaleta, B. Rosen, B. Fischl, S. Corkin, H. Diana Rosas, A. Dale, Neurobiol. Aging 26, 1215–1227 (2005)

    Article  Google Scholar 

  5. Y. Assaf, O. Pasternak, J. Mol. Neurosci. 34, 51–61 (2008)

    Article  Google Scholar 

  6. R. von Kummer, I. Dzialowski, J. Gerber, J. Neuroradiol. 42, 47–54 (2014)

    Article  Google Scholar 

  7. A. Curra, N. Modugno, M. Inghilleri, M. Manfredi, M. Hallett, A. Berardelli, Neurology. 59, 1851–1859 (2002)

    Article  Google Scholar 

  8. M.S. George, S.H. Lisanby, H.A. Sackeim, Arch. Gen. Psychiatry 56, 300–311 (1999)

    Article  Google Scholar 

  9. C. Pierpaoli, P. Jezzard, P.J. Basser, A. Barnett, G. Di Chiro, Radiology 201, 637–648 (1996)

    Article  Google Scholar 

  10. B.P. Witwer, R. Moftakhar, K.M. Hasan, P. Deshmukh, V. Haughton, A. Field, K. Arfanakis, J. Noyes, C. Moritz, E. Meyerand, H. Rowley, A. Alexander, B. Badie, J. Neurosurg. 97, 568–575 (2002)

    Article  Google Scholar 

  11. D. Le Bihan, J.F. Mangin, C. Poupon, C.A. Clark, S. Pappata, N. Molko, H. Chabriat, Diffusion tensor imaging: concepts and applications. J. Magn. Reson. Imaging 13, 534–546 (2001)

    Article  Google Scholar 

  12. N.G. Papadakis, D. Xing, C.L.-H. Huang, L.D. Hall, T.A. Carpenter, J. Magn. Reson. 137, 67–82 (1999)

    Article  ADS  Google Scholar 

  13. Q. Yang, B.M. Tress, P.A. Barber, P.M. Desmond, D.G. Darby, R.P. Gerraty, T. Li, S.M. Davis, Stroke 30, 2382–2390 (1999)

    Article  Google Scholar 

  14. B. Stieltjes, W.E. Kaufmann, P.C. van Zijl, K. Fredericksen, G.D. Pearlson, M. Solaiyappan, S. Moria, Neuroimage. 14, 723–735 (2001)

    Article  Google Scholar 

  15. Z. Liu, Y. Li, X. Zhang, S. Savant-Bhonsale, M. Chopp, Stroke 39, 2571–2577 (2008)

    Article  Google Scholar 

  16. A.G. Sorensen, O. Wu, W.A. Copen, T.L. Davis, R.G. Gonzalez, W.J. Koroshetz, T.G. Reese, B.R. Rosen, V.J. Wedeen, R.M. Weisskoff, Radiology 212, 785–792 (1999)

    Article  Google Scholar 

  17. J. Wardlaw, S. Keir, M. Bastin, P. Armitage, A. Rana, Neurology. 59, 1381–1387 (2002)

    Article  Google Scholar 

  18. G. Thomalla, V. Glauche, M.A. Koch, C. Beaulieu, C. Weiller, J. Röther, Neuroimage. 22, 1767–1774 (2004)

    Article  Google Scholar 

  19. Z. Xu, Q. Guo, G. Chen, M. Li, P. Lin, Chin. J. Pract. Nerv. Dis. 11, 4–6 (2009)

    Google Scholar 

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Authors and Affiliations

  1. Department of Rehabilitation, Sichuan Academy of Medical Sciences, Sichuan Provincial People’s Hospital, No. 32 West Second Section First Ring Road, Chengdu, 610000, Sichuan, China

    Yufeng Li, Qian Yu, Yi Li, Bo Peng, Yamei Li, Jing Fu, Ziyu Wang & Shiqiong Zhu

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  1. Yufeng Li
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  2. Qian Yu
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  3. Yi Li
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Correspondence to Shiqiong Zhu.

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Li, Y., Yu, Q., Li, Y. et al. Magnetic Resonance Diffusion Tensor Imaging in Evaluating Transcranial Magnetic Stimulation Treatment for Acute Ischemic Stroke: A Retrospective Study. Appl Magn Reson 47, 255–263 (2016). https://doi.org/10.1007/s00723-015-0753-5

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