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Microvascular Imaging Using Compressed Sensing at 7T MRI: A Preliminary Study

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Abstract

The aim of this study was to obtain high-resolution images with a short acquisition time using a compressed sensing (CS) technique for microvascular imaging, especially of the lenticulostriate arteries (LSAs), with 7T magnetic resonance imaging (MRI). Initially, two different radio frequency (RF) coils, birdcage and multi-channel phased array, were tested to compare images of micro-vessels acquired using the CS technique with those acquired using conventional magnetic resonance angiography (MRA) at 7T MRI. High-resolution CS MRA as well as low- and high-resolution conventional time-of-flight MRA images obtained with a multi-channel RF coil was compared to evaluate the feasibility of the CS technique for microvascular imaging. Signal intensities were then used to quantitatively estimate vessel sizes. Compared to low-resolution MRA, the CS technique improved the depiction of the LSAs and provided a substantially reduced partial volume effect of the vessels. Despite the short acquisition time of the CS technique, it clearly depicted the LSA morphology almost as well as the high-resolution MRA. The measured size difference between micro-vessels that were analyzed using the CS technique and those analyzed using high-resolution MRA was about 20 %; however, the difference between the high-resolution and the low-resolution MRA was as high as 100 %. This study evaluated the feasibility of the CS technique for microvascular imaging with 7T MRI. A CS technique that combines high-resolution imaging with a short acquisition time would be a very effective method for microvascular imaging in both research and clinical studies.

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Acknowledgments

This work was supported by Gachon University, Incheon, Republic of Korea (Grant Number: GCU-2015-0061 & GCU-2015-5030).

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Authors and Affiliations

  1. Bioimaging Research Team, Korea Basic Science Institute, Ochang, Chungbuk, Republic of Korea

    Chan-A Park

  2. Graduate School of Information Science and Kansei Fukushi Research Institute, Tohoku University, Sendai, Japan

    Daehun Kang

  3. Neuroscience Research Institute, Gachon University, Incheon, Republic of Korea

    Young-Don Son, Hang-Keun Kim & Chang-Ki Kang

  4. Department of Biomedical Engineering, College of Health Science, Gachon University, Incheon, Republic of Korea

    Young-Don Son & Hang-Keun Kim

  5. Department of Radiological Science, College of Health Science, Gachon University, Incheon, Republic of Korea

    Chang-Ki Kang

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  1. Chan-A Park
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  2. Daehun Kang
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Correspondence to Chang-Ki Kang.

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Park, CA., Kang, D., Son, YD. et al. Microvascular Imaging Using Compressed Sensing at 7T MRI: A Preliminary Study. Appl Magn Reson 46, 1189–1197 (2015). https://doi.org/10.1007/s00723-015-0713-0

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  • DOI: https://doi.org/10.1007/s00723-015-0713-0

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