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Bench-Top Type In Vivo EPR Spectrometer for Estimating the Renal Reducing Ability of a Rat

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An Erratum to this article was published on 16 November 2012

Abstract

A main electromagnet optimized for electron paramagnetic resonance (EPR) measurements of rats by using a surface loop resonator with a loop diameter of 10 mm was designed. The fabricated main electromagnet was ca. 420 mm in diameter, ca. 240 mm in width, and ca. 60 kg in weight. When a static magnetic field of 25 mT was generated at the center of the main electromagnet, its deviation in a sphere space with a diameter of 10 mm was <0.02 mT. In this condition, the temperature elevation on the surface of the magnet was negligible for the measurement time assumed for in vivo study. Using this magnet, a bench-top type in vivo EPR spectrometer could be obtained, which made it possible to perform EPR measurements for estimating the renal reducing ability of a rat.

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Notes

  1. In this article, “surface loop resonator” and “SLR” have been used synonymously with “surface-coil-type resonator” and “SCR” previously used.

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Acknowledgments

We thank the late Dr. T. Yoshimura of Yamagata Promotional Organization for Industrial Technology for his assistance in designing the RF circuits.

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Authors and Affiliations

  1. Department of Pharmaceutical Sciences, International University of Health and Welfare, 2600-1 Kitakanemaru, Otawara, 324-8501, Japan

    Hidekatsu Yokoyama

  2. Yamagata Promotional Organization for Industrial Technology, 2-2-1 Matsuei, Yamagata, 990-2473, Japan

    Hidekatsu Yokoyama

  3. Yamagata Research Institute of Technology, 2-2-1 Matsuei, Yamagata, 990-2473, Japan

    Toshiyuki Sato

  4. Center for Clinical Medicine and Research, International University of Health and Welfare, 537-3 Iguchi, Nasushiobara, 329-2763, Japan

    Takaaki Oteki

Authors
  1. Hidekatsu Yokoyama
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  2. Toshiyuki Sato
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  3. Takaaki Oteki
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Corresponding authors

Correspondence to Hidekatsu Yokoyama or Takaaki Oteki.

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Toshiyuki Sato : Deceased

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Yokoyama, H., Sato, T. & Oteki, T. Bench-Top Type In Vivo EPR Spectrometer for Estimating the Renal Reducing Ability of a Rat. Appl Magn Reson 43, 421–430 (2012). https://doi.org/10.1007/s00723-012-0343-8

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  • DOI: https://doi.org/10.1007/s00723-012-0343-8

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