Abstract.
Using a newly designed liquid-state dynamic nuclear polarization (DNP) spectrometer operating at a magnetic field of 9.2 T, a DNP enhancement of −4.0(1) was achieved for protons in a liquid water-TEMPOL sample. The DNP mechanism was observed to be the Overhauser effect, where the polarization was transfered via electron–proton dipolar relaxation. At full microwave power, the sample was heated by 17 K above room temperature, causing a significant increase in the DNP enhancement. These first results from the Frankfurt liquid-state DNP spectrometer represent a significant step towards the application of DNP to large biomolecules in the liquid state.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Overhauser, A.W.: Phys. Rev. 92, 411 (1953)
Wind, R.A., Duijvestijn, M.J., van der Lugt, C., Manenschijn, A., Vriend, J.: Prog. Nucl. Magn. Reson. Spectrosc. 17, 33 (1985)
Atsarkin, V.A.: Sov. Phys. Usp. 21, 725 (1978)
Hausser, K.H.: Z. Phys. 183, 265 (1965)
Jackson, J.D.: Classical Electrodynamics, 3rd edn. Wiley, New York (1999)
Denysenkov, V.P., Prandolini, M.J., Krahn, A., Gafurov, M., Endeward, B., Prisner, T.F.: Appl. Magn. Reson. 34, 289–299 (2008)
Hausser, K.H., Stehlik, D.: Adv. Magn. Reson. 3, 79 (1968)
Müller-Warmuth, W., Meise-Gresch, K.: Adv. Magn. Reson. 11, 1 (1983)
Hall, D.A., Maus, D.C., Gerfen, G.J., Inati, S.J., Becerra, L.R., Dahlquist, F.W., Griffin, R.G.: Science 276, 930 (1997)
Hu, K.-N., Yu, H.-H., Swager, T.M., Griffin, R.G.J.: Am. Chem. Soc. 126, 10844 (2004)
Bajaj, V.S., Hornstein, M.K., Kreischer, K.E., Sirigiri, J.R., Woskov, P.P., Mak-Jurkauskas, M.L., Herzfeld, J., Temkin, R.J., Griffin, R.G.: J. Magn. Reson. 189, 251 (2007)
Loening, N.M., Rosay, M., Weis, V., Griffin, R.G.: J. Am. Chem. Soc. 124, 8808 (2002)
Wu, T., Kendell, K.R., Felmlee, J.P., Lewis, B.D., Ehman, R.L.: Med. Phys. 27, 221 (2000)
Wind, R.A., Ardenkjaer-Larsen, J.-H.: J. Magn. Reson. 141, 347 (1999)
Armstrong, B.D., Han, S.: J. Chem. Phys. 127, 104508 (2007)
Höfer, P., Parigi, G., Luchinat, C., Carl, P., Guthausen, G., Reese, M., Carlomagno, T., Griesinger, C., Bennati, M.: J. Am. Chem. Soc. 130, 3254–3255 (2008)
Borah, B., Bryant, R.G.: J. Chem. Phys. 75, 3297 (1981)
Author information
Authors and Affiliations
Additional information
Authors' address: Mark Prandolini, Institute of Physical and Theoretical Chemistry, J. W. Goethe University Frankfurt, Max-von-Laue-Strasse 7, 60438 Frankfurt am Main, Germany
Rights and permissions
Open Access This is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License ( https://creativecommons.org/licenses/by-nc/2.0 ), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
About this article
Cite this article
Prandolini, M., Denysenkov, V., Gafurov, M. et al. First DNP Results from a Liquid Water-TEMPOL Sample at 400 MHz and 260 GHz. Appl Magn Reson 34, 399–407 (2008). https://doi.org/10.1007/s00723-008-0128-2
Received:
Issue Date:
DOI: https://doi.org/10.1007/s00723-008-0128-2