Spontaneous self-resolution of vitreomacular diseases: a three-case report

  • Gregor Kastl
case report



In many cases, macular hole and epiretinal membrane require surgical therapy. In rare cases, spontaneous resolution is possible.

Patients and methods

Three cases of vitreoretinal diseases are presented: one case of spontaneous closure of an idiopathic stage III macular hole and two cases of spontaneous self-resolution of an epiretinal membrane.


The idiopathic stage III macular hole resolved after a period of more than 6 years of observation. The idiopathic epiretinal membranes separated spontaneously after several months to years of observation.


Awareness of the possible self-resolution of macular hole and epiretinal membrane is clinically relevant in the treatment of these conditions.


Macular hole Spontaneous closure Epiretinal membrane Spontaneous self-resolution OCT 

Spontanremission vitreomakulärer Erkrankungen: Bericht über 3 Fälle



Beim idiopathischen Makulaforamen und der epimakulären Gliose handelt es sich um Erkrankungen, die in vielen Fällen operativ behandelt werden. In seltenen Fällen kann es jedoch zur Spontanremission kommen.


Drei Fälle vitreoretinaler Erkrankungen werden vorgestellt. Der erste Fall behandelt den Spontanverschluss eines idiopathischen Makulaforamens (Stadium III), die anderen beiden Fälle betreffen die spontane Rückbildung einer epiretinalen Membran.


Das idiopathische Makulaforamen (Stadium III) schloss sich nach mehr als 6 Jahren ohne Verbesserung der Sehschärfe. Die beiden Fälle einer epiretinalen Membran bildeten sich nach Monaten bzw. Jahren spontan zurück.


Makulaforamina können sich spontan schließen, und eine epiretinale Gliose kann sich spontan zurückbilden. Die Kenntnis hierüber erscheint klinisch relevant, etwa bei der Indikationsstellung zu einer operativen Therapie.


Makulaforamen Spontanverschluss Epiretinale Gliose Spontanremission OCT 



Many thanks to Dr. Aaron Winter, Department of Ophthalmology, Dalhousie University Halifax, Canada, for checking the manuscript.

Compliance with ethical guidelines

Conflict of interest

G. Kastl declares that he has no competing interests.

Ethical standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.


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Copyright information

© Springer-Verlag GmbH Austria, ein Teil von Springer Nature 2018

Authors and Affiliations

  1. 1.Augenklinik Herzog Carl TheodorMunichGermany

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