Summary
The human papilloma viruses (HPVs) are known to be causal factors in the development malign tumors. The study investigates a smear test, routinely used in gynecology for HPV-diagnosis in cervical lesions, for oral HPV-detection. The procedure is evaluated and the reliability and potential failures are evaluated. The Digene Cervical Sampler HC2 Hybrid Capture® procedure represents a reliable and low-price method in the diagnosis of high and low risk oral HPV-infection.
Zusammenfassung
Humane Papillomaviren (HPVs) gelten als kausale Ursache bei der Entstehung maligner Tumore. Die vorliegende Untersuchung bewertet die Anwendung der in der Gynäkologie als Routineverfahren verwendeten HPV-Abstrichmethode (Digene Cervical Sampler®) im Rahmen der oralen HPV-Diagnostik. Es wird die Methodik des Verfahrens beschrieben, Reliabilitätsbestimmungen und Fehlermöglichkeiten bewertet und die Studienergebnisse mit Ergebnissen der aktuellen Literatur verglichen. Die Digene Cervical Sampler HC2 Hybrid Capture®-Diagnostik (Digene Cervical Sampler® in Kombination mit Hybrid Capture II® Assay) stellt ein zuverlässiges und kostengünstiges Verfahren in der oralen high-risk- und low-risk-HPV-Diagnostik dar.
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Ferderführender Autor: DDr. Daniel Dalla Torre, Klinik für MKG-Chirurgie, Medizinische Universität Innsbruck, Anichstrasse 35, 6020 Innsbruck, Tel.: 0512/504/82509, E-Mail: daniel.dalla-torre@uki.at
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Dalla Torre, D., Sölder, E., Burtscher, D. et al. Die orale Bürstenabstrichmethode zur Bestimmung von humanen Papillomavirus (HPV)-Infektionen. Stomatologie 109, 35–39 (2012). https://doi.org/10.1007/s00715-012-0154-4
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DOI: https://doi.org/10.1007/s00715-012-0154-4