Summary.
Because of the low stability of the benzyl ester linkage in benzyl 1,2:3,5-di-O-benzylidene-α-D-glucofuranuronate during the removal of the benzylidene groups by acid hydrolysis and/or hydrogenolysis, 4-methoxybenzylidene groups were used to block the free hydroxyl groups of D-glucuronic acid. Several benzyl esters of D-glucuronic acid were prepared, and their relative rates of acid catalyzed hydrolysis were determined by liquid-chromatographic separation of the reaction mixture and subsequent diode array detection.
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Received May 22, 2000. Accepted (revised) July 17, 2000
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Poláková, M., Joniak, D. & Ďuriš, M. Preparation of Some Benzyl D-Glucuronatesfrom 4-Methoxybenzylidene Derivatives of D-Glucuronic Acid. Monatshefte fuer Chemie 131, 1197–1205 (2000). https://doi.org/10.1007/s007060070028
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DOI: https://doi.org/10.1007/s007060070028