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Synthesis of Structurally Related Purines: Benzimidazo[1,2-a]pyridines, Benzimidazo-[1,2-c]pyrimidines, and Pyrazolo-[1,5-a]pyrimidines

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Summary.

 Reactions of sodium salts of 3-hydroxymethylene-2-alkanones with 2-cyanomethylbenzimidazole afforded benzimidazo[1,2-a]pyridines. Analogues reactions with 2-aminobenzimidazole and 5-aminopyrazoles afforded benzimidazo[1,2-c]pyrimidines and pyrazolo[1,5-a]pyrimidines.

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Authors and Affiliations

  1.  Department of Chemistry, Faculty of Science, Helwan University, Helwan, Cairo, Egypt, , , , , , EG

    Galal H. Elgemeie & Nadia H. Metwally

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  1. Galal H. Elgemeie
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  2. Nadia H. Metwally
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Received December 12, 1999. Accepted (revised) February 12, 2000

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Elgemeie, G., Metwally, N. Synthesis of Structurally Related Purines: Benzimidazo[1,2-a]pyridines, Benzimidazo-[1,2-c]pyrimidines, and Pyrazolo-[1,5-a]pyrimidines. Monatshefte fuer Chemie 131, 779–785 (2000). https://doi.org/10.1007/s007060050025

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  • DOI: https://doi.org/10.1007/s007060050025

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