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Synthesis of acenaphtho[1',2':4,5]pyrrolo[2,3-d]pyrimidine derivatives via one-pot three-component reaction

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Abstract

An expedient three-component reaction for the synthesis of acenaphtho[1',2':4,5]pyrrolo[2,3-d]pyrimidine, (hydropyrimidinyl) acenaphtho[1',2':4,5]pyrrolo[2,3-d]pyrimidine, and phenanthro[9,10-b]pyrimido[4,5-e][1,4]oxazine is described. The desired products were obtained in good to high yields. This work has the advantages of convenient operation, mild reaction conditions, simple workup, and provides an entry point to fused heterocyclic structures.

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Acknowledgements

We gratefully acknowledge the financial support of this research from Imam Khomeini International University.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Imam Khomeini International University, Qazvin, Iran

    Zeinab Amiri & Mohammad Bayat

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  1. Zeinab Amiri
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  2. Mohammad Bayat
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Correspondence to Mohammad Bayat.

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Amiri, Z., Bayat, M. Synthesis of acenaphtho[1',2':4,5]pyrrolo[2,3-d]pyrimidine derivatives via one-pot three-component reaction. Monatsh Chem 152, 1291–1296 (2021). https://doi.org/10.1007/s00706-021-02836-1

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  • DOI: https://doi.org/10.1007/s00706-021-02836-1

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