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Ozonation: effective way for removal of pharmaceuticals from wastewater

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Abstract

The objective of the presented paper is to characterize the effectiveness of the removal of pharmaceuticals from wastewater during ozonation in laboratory-scale conditions. Almost 100 pharmaceuticals and their metabolites from different therapeutic classes were studied in effluent from the wastewater treatment plant, Devínska Nová Ves, used for ozonation. Telmisartan, diclofenac, and fexofenadine were found at the highest concentrations (1800 ng/dm3, 680 ng/dm3, and 620 ng/dm3, respectively). The concentrations of another 13 pharmaceuticals and metabolites exceeded 100 ng/dm3, and the rest of the compounds were below 100 ng/dm3. These water samples underwent ozonation in intervals of 0–10 min. The flow of ozone during the test was 50 mg O3/min. The results show that the removal of pharmaceuticals is significant after the first minute of ozonation, when most of the studied compounds were below the limit of quantification. The total concentration of the studied compounds after the first minute decreased to 190 ng/dm3 (97.2% removal efficiency). More than 99% removal efficiency was achieved after 10 min of ozonation.

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References

  1. Tran NH, Gin KYH (2017) Sci Total Environ 1503:599–600

    Google Scholar 

  2. Couto CF, Lange LC, Amaral MCS (2019) J Water Process Eng 32:100927

    Article  Google Scholar 

  3. Rizzo L, Malato S, Antakyali D, Bertsou VG, Dolic MB, Gernjak W, Heath E, Ivancev-Tumbas I, Karaolia P, Lado Ribeiro AR, Mascolo G, McArdell ChS, Schaar H, Silva AMT, Fatta-Kassinos D (2019) Sci Total Environ 655:986

    Article  CAS  Google Scholar 

  4. Peña A, Delgado-Moreno L, Rodríguez-Liébana JA (2019) Sci Total Environ 134:468

    Google Scholar 

  5. Altmann J, Ruhl AS, Zietzschmann F, Jekel M (2014) Water Res 55:185

    Article  CAS  Google Scholar 

  6. Czölderová M, Behúl M, Filip J, Zajíček P, Grabic R, Vojs-Staňová A, Gál M, Kerekeš K, Híveš J, Ryba J, Rybanská M, Brandeburová P, Mackuľak T (2018) Chem Eng J 349:269

    Article  Google Scholar 

  7. Guillossou R, Le Roux J, Mailler R, Pereira-Derome CS, Varrault G, Bressy A, Vulliet E, Morlay C, Nauleau F, Rocher V, Gasperi J (2020) Water Res 172:115487

    Article  CAS  Google Scholar 

  8. Hansen KMS, Spiliotopoulou A, Chhetri RK, Casas ME, Bester K, Andersen HR (2016) Chem Eng J 290:507

    Article  CAS  Google Scholar 

  9. Marcelino RBP, Leão MMD, Lago RM, Amorim CC (2017) J Environ Manag 195:110

    Article  CAS  Google Scholar 

  10. Wang J, Chen H (2020) Sci Total Environ 704:135249

    Article  CAS  Google Scholar 

  11. Hoigné J, Bader H (1976) Water Res 10:377

    Article  Google Scholar 

  12. Keysers C, Grunebaum T, Thöle, Pinnekamp J (2013) Micropol and Ecohazard 2013. The 8th IWA Specialist Conference on Assessment and Control of Micropollutants/Hazardous Substances in Water

  13. Knopp G, Prasse C, Ternes TA, Cornel P (2016) Water Res 100:580

    Article  CAS  Google Scholar 

  14. Margot J, Kienle C, Magnet A, Weil M, Rossi L, Felippe Alencastro L, Abegglen C, Thonney D, Chevre N, Scharer M, Barrz DA (2013) Sci Total Environ 480:461–462

    Google Scholar 

  15. Lee Y, von Gunten U (2012) Water Res 46:6177

    Article  CAS  Google Scholar 

  16. Borowska E, Bourgin M, Hollender J, Kienle C, McArdell ChS, von Gunten U (2016) Water Res 94:350

    Article  CAS  Google Scholar 

  17. Derco J, Valičková M, Šilhárová K, Dudáš J, Luptáková A (2013) Chem Pap 67:1585

    Article  CAS  Google Scholar 

  18. Fedorova G, Randak T, Lindberg RH, Grabic R (2013) Rapid Commun Mass Spectrom 27:1751

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the Slovak Research and Development Agency under the contracts No. APVV 0122-12 and APVV 0119-17, by the Ministry of Education, Youth and Sports of the Czech Republic via project “CENAKVA” (No. LM2018099).

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Authors and Affiliations

  1. Institute of Chemical and Environmental Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, 812 37, Bratislava, Slovak Republic

    Petra Szabová, Kristína Hencelová, Zuzana Sameliaková & Igor Bodík

  2. Messer Tatragas spol. s r.o., Chalupkova 9, 819 44, Bratislava, Slovak Republic

    Terézia Marcová

  3. Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, University of South Bohemia in České Budějovice, Zátiší 728/II, 389 25, Vodňany, Czech Republic

    Andrea Vojs Staňová & Kateřina Grabicová

  4. Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Ilkovičova 6, 842 15, Bratislava, Slovak Republic

    Andrea Vojs Staňová

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  1. Petra Szabová
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  2. Kristína Hencelová
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  5. Andrea Vojs Staňová
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  6. Kateřina Grabicová
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Correspondence to Petra Szabová.

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Szabová, P., Hencelová, K., Sameliaková, Z. et al. Ozonation: effective way for removal of pharmaceuticals from wastewater. Monatsh Chem 151, 685–691 (2020). https://doi.org/10.1007/s00706-020-02600-x

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  • DOI: https://doi.org/10.1007/s00706-020-02600-x

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