Skip to main content
SpringerLink
Log in

The accuracy of continuous glucose monitoring system by the athlete with diabetes mellitus type 1

  • Original Paper
  • Published:
Monatshefte für Chemie - Chemical Monthly Aims and scope Submit manuscript

Abstract

This article deals with assessment of accuracy of the widely used glucose sensors MMT-7002 (Medtronic, USA), for continuous monitoring of glucose levels. The samples were gained from a 35-year-old sportswoman with diagnosed DM type 1. The sampling was carried out by her common daily as well as extreme physical and sport activities. The evaluated data were collected during 45 months, 56 sensors were used and 603 calibrations were carried out. The tested glucose sensor operates on the principle of a needle sensor, which electrochemically evaluates the reaction products catalyzed by glucose oxidase. Accuracy was evaluated by Clarke error grid analysis and the results were compared with the accuracy given by the sensor manufacturer. The measurements carried out by the tested sensor in the range of the normal glucose levels, realized under usual life conditions and by sport activities were even more accurate than those given by the manufacturer. However, in the regions of hypoglycemia or hyperglycemia, the number of errors was higher than specified by the manufacturer. The continuous glucose monitoring proved to be sufficiently accurate for prevention of acute complications in patients with DM type 1 during their common as well as extreme sport and physical activities.

Graphical abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. UZIS (2011) Diabetes care management (In Czech). ÚZIS ČR, Prague

    Google Scholar 

  2. Friedecky B, Zima T, Kratochvil A, Springer D (2012) Diabetes mellitus—laboratory diagnosis and patient status monitoring (in Czech). Czech Society of Clinical Biochemistry. http://www.cskb.cz/res/file/doporuceni/DM_verze%202012.pdf

  3. Mueller AJ, Hasslacher C, Krivanek R, Knuth M, Nikolaus KS, Kuester F, Theinert S (2013) Diabetes Technol Ther 15:A68

    Google Scholar 

  4. Vashist SK (2012) Anal Chim Acta 750:16

    Article  CAS  PubMed  Google Scholar 

  5. Vashist SK (2013) Diagnostics (Basel) 3:385

    Article  CAS  Google Scholar 

  6. Vashist SK, Luong JHT (2016) Point-of-care glucose detection for diabetic monitoring and management. CRC Press, Florida

    Book  Google Scholar 

  7. English BE (2012) Eur Endocrinol 8:18

    Article  Google Scholar 

  8. Broz J (2009) DIAstyl 5:24

    Google Scholar 

  9. Vashist SK, Zheng D, Al-Rubeaan K, Luong JHT, Sheu FS (2011) Anal Chim Acta 703:124

    Article  CAS  PubMed  Google Scholar 

  10. Jirkovska A (2009) Remedia 2:1

    Google Scholar 

  11. Pickova K (2013) Accuracy of glucometers (in Czech). Aidia. http://www.mojecukrovka.cz/clanek/presnost-mereni-glukometru/

  12. Boyne MS, Silver DM, Kaplan J, Saudek CD (2003) Diabetes 52:2790

    Article  CAS  PubMed  Google Scholar 

  13. Anonymous (2011) Diabetes mellitus (in Czech). http://cukrovka-ocima-biochemie.blog.cz/

  14. Kovatchev B, Anderson S, Heinemann L, Clarke W (2008) Diabetes Care 31:1160

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Wentholt IM, Hoekstra JB, DeVries JH (2006) Diabetes Care 29:1805

    Article  PubMed  Google Scholar 

  16. Clarke WL, Cox D, Gonderfrederick LA, Carter W, Pohl SL (1987) Diabetes Care 10:622

    Article  CAS  PubMed  Google Scholar 

  17. Commission European (2003) ISO 15197:2003 In vitro diagnostic test systems—requirements for blood-glucose monitoring systems for self-testing in managing diabetes mellitus. European Committee for Standardization, Brussels

    Google Scholar 

  18. Zourek M (2012) Zdravotnicke Noviny 3:2

    Google Scholar 

  19. Honsova S, Navratil T (2011) Evaluating the Accuracy of Continuous Glucose Monitoring by the Patient through Continuous Glucose Error Grid Analysis. In: Navratil T, Barek J (eds) XXXI Moderni Elektrochemicke Metody (Modern Electrochemical Methods XXXI), Jetrichovice. Best Servis, p 59

  20. Honsova S, Navratil T (2013) Continuous Glucose Monitoring by Real Time Sensor in Interstitial Fluid. In: Navratil T, Fojta M, Peckova K (eds) XXXIII Moderni Elektrochemicke Metody (Modern Electrochemical Methods XXXIII), Jetrichovice. Best Servis, p 63

  21. Anonymous (2011) Guardian Real Time User Guide. http://www.minimed.com/pdf/guardian_real_time_user_guide.pdf

  22. Hasanbegovic S (2010) HealthMED 4:615

    Google Scholar 

  23. Clarke WL, Anderson S, Farhy L, Breton M, Gonder-Frederick L, Cox D, Kovatchev B (2005) Diabetes Care 28:2412

    Article  CAS  PubMed  Google Scholar 

  24. Clarke W, Stacey A, Kovatchev B (2008) Cur Diabetes Rev 4:7

    Google Scholar 

  25. Mraz M, Svacina S, Haluzik M (2009) Diabetol Metabol Endokr Výživa 12:71

    Google Scholar 

  26. Cauchy E (2009) Vade-mecum of mountain and travel medicine (in Czech) (trans: Hoschlova K). Cohen Property & Devolopment, Prague

    Google Scholar 

  27. Clarke W, Kovatchev B (2009) Diabetes Technol Ther 11:S45

    Article  CAS  PubMed  Google Scholar 

  28. Medtronic (2011) Guardian® REAL-time continuous glucose monitoring system. (4. 3. 2011)

Download references

Acknowledgements

The article was written in the framework of the scientific branch development program UK FTVS PRVOUK No. P38 Biological-Sciences Aspects of Human Movement Studies (E. Kohliková), PRVOUK No. P39 Social-Sciences Aspects of Human Movement Studies (S. Vokounová-Honsová) and under financial support of the Czech Science Foundation (GA ČR No. 17-03868S) (T. Navrátil).

Author information

Authors and Affiliations

  1. Faculty of Physical Education and Sport, Charles University, José Martího 31, 162 52, Prague 6, Czech Republic

    Šárka Vokounová-Honsová & Eva Kohlíková

  2. J. Heyrovský Institute of Physical Chemistry of the Czech Academy of Sciences, Dolejškova 3, 182 23, Prague 8, Czech Republic

    Tomáš Navrátil

  3. Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Kateřinská 32, 121 08, Prague 2, Czech Republic

    Tomáš Navrátil

Authors
  1. Šárka Vokounová-Honsová
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tomáš Navrátil
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Eva Kohlíková
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Tomáš Navrátil.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Vokounová-Honsová, Š., Navrátil, T. & Kohlíková, E. The accuracy of continuous glucose monitoring system by the athlete with diabetes mellitus type 1. Monatsh Chem 149, 1659–1669 (2018). https://doi.org/10.1007/s00706-018-2236-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00706-018-2236-5

Keywords

Search

Navigation