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A simple and one-pot multi-component reaction to the synthesis of methylenebisamides

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Abstract

This work described a simple and efficient method for the synthesis of some methylenebisamide derivatives. The reaction is carried out via a simple multi-component reaction between arylaldehydes, DMSO, and hydroxylamine hydrochloride. Short reaction times, excellent yields of products, inexpensive and readily available starting material, eco-friendly method, easy work-up, and high atom economy are the main advantages of this reaction.

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Acknowledgements

I gratefully acknowledge the financial support from the Research Council of Payame Noor University (PNU), Tehran, Iran.

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Authors and Affiliations

  1. Department of Chemistry, Payame Noor University, P. O. Box, Tehran, 19395-3697, Iran

    Bagher Mohammadi & Bahareh Rezaei Khorrami

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  1. Bagher Mohammadi
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  2. Bahareh Rezaei Khorrami
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Correspondence to Bagher Mohammadi.

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Mohammadi, B., Khorrami, B.R. A simple and one-pot multi-component reaction to the synthesis of methylenebisamides. Monatsh Chem 149, 1089–1092 (2018). https://doi.org/10.1007/s00706-017-2124-4

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  • DOI: https://doi.org/10.1007/s00706-017-2124-4

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