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Monatshefte für Chemie - Chemical Monthly

, Volume 148, Issue 1, pp 139–148 | Cite as

Design and synthesis of basic ionic liquids for the esterification of triterpenic acids

  • Anna K. Ressmann
  • Maria Schneider
  • Peter Gaertner
  • Matthias Weil
  • Katharina Bica
Original Paper

Abstract

We present the design and synthesis of Brønsted-basic ionic liquids and investigate their application in the microwave-assisted esterification of betulinic acid, aiming towards a benign and pyridine-free manufacturing process of the anti-HIV drug, bevirimat.

Graphical abstract

Keywords

Ionic liquids Natural products Green chemistry Microwave-assisted synthesis Crystal structure 

Notes

Acknowledgements

We are grateful to Botanical Garden Vienna for the collections and supply of bark from platanus acerifola for the preparation of reference material. The X-ray centre of TU Wien is acknowledged for providing access to the single crystal diffractometer.

Supplementary material

706_2016_1889_MOESM1_ESM.docx (24 kb)
Supplementary material 1 (DOCX 23 kb)

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Copyright information

© Springer-Verlag Wien 2016

Authors and Affiliations

  • Anna K. Ressmann
    • 1
  • Maria Schneider
    • 1
  • Peter Gaertner
    • 1
  • Matthias Weil
    • 2
  • Katharina Bica
    • 1
  1. 1.Institute of Applied Synthetic ChemistryTU WienViennaAustria
  2. 2.Institute for Chemical Technologies and AnalyticsTU WienViennaAustria

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