Monatshefte für Chemie - Chemical Monthly

, Volume 147, Issue 8, pp 1349–1352 | Cite as

Application of direct analysis in real time (DART) and direct inlet probe (DIP-APCI) mass spectrometry in the context of industrial sample analysis

  • Stefan Viehbeck
  • Frank-Michael MatysikEmail author
Short communication


In today’s industry, quick and reliable analytical methods play an important role for quality control. On that account, two emerging techniques, namely direct inlet probe-atmospheric pressure chemical ionization (DIP-APCI) and direct analysis in real time (DART) mass spectrometry, are particularly promising. In case of a DIP-APCI source, small amounts of solid or liquid samples can be studied without sample pre-treatment. A similar system is the DART ion source. In addition to the analysis of solid and liquid samples without pre-separation, this ion source offers the possibility to scan the surface of a sample. A method for industrial sample analysis focusing on the study of delamination of coatings from a panel was developed using DIP-APCI-Q-TOF-MS and DART-Q-TOF-MS, respectively. Comparative studies based on the conventional pyrolysis–GC–MS were carried out.

Graphical abstract


Atmospheric pressure ion source Direct analysis in real time Direct inlet probe Ambient mass spectrometry Analysis of surfaces Material science 



We would like to express our gratitude to both companies SIM GmbH and IonSense/KR-Analytical for providing the necessary equipment, information, and support.


  1. 1.
    Penning FM (1927) Naturwissenschaften 15:818CrossRefGoogle Scholar
  2. 2.
    Cody RB (2009) Anal Chem 81:1101CrossRefGoogle Scholar
  3. 3.
    Gross JH (2014) Anal Bioanal Chem 406:63CrossRefGoogle Scholar
  4. 4.
    Wang C, Zhu H, Cai Z, Song F, Liu Z, Liu S (2013) Anal Bioanal Chem 405:319Google Scholar
  5. 5.
    Roberts ES, Boudreau BA, Brown DW, McQuade KL, Remsen EE (2016) Anal Methods 8:673CrossRefGoogle Scholar
  6. 6.
    Krieger S, von Trotha A, Leung KS, Schmitz OJ (2013) Anal Bioanal Chem 405:1373CrossRefGoogle Scholar
  7. 7.
    Carroll DI, Dzidic I, Stillwell RN, Haegele KD, Horning EC (1975) Anal Chem 47:2369CrossRefGoogle Scholar
  8. 8.
    Krieger S, Schmitz OJ (2014) Rapid Commun Mass Spectrom 28:1862CrossRefGoogle Scholar
  9. 9.
    Davis R, Frearson M (1987) Mass spectrometry—analytical chemistry by open learning. Wiley, Chichester/New YorkGoogle Scholar

Copyright information

© Springer-Verlag Wien 2016

Authors and Affiliations

  1. 1.Institute for Analytical Chemistry, Chemo- and BiosensorsUniversity of RegensburgRegensburgGermany

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