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Ultrasonic-assisted synthesis of carbodiimides from N,N′-disubstituted thioureas and ureas

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Abstract

A facile and efficient sonochemical method for the preparation of carbodiimides from their corresponding thioureas or ureas was described. Using Ph3P–I2 combination in the presence of triethylamine, various diaryl, aryl–alkyl, as well as dialkyl substituted substrates could be converted into carbodiimides in good-to-excellent yields within short reaction times under mild conditions with simple experimental setup.

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Acknowledgments

Financial support from the Thailand Research Fund through the Royal Golden Jubilee Ph.D. Program (Grant No. PHD/0086/2557) to C.D. is gratefully acknowledged.

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Authors and Affiliations

  1. Department of Chemistry, Chiang Mai University, Chiang Mai, Thailand

    Chuthamat Duangkamol, Mookda Pattarawarapan & Wong Phakhodee

Authors
  1. Chuthamat Duangkamol
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  2. Mookda Pattarawarapan
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  3. Wong Phakhodee
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Corresponding author

Correspondence to Wong Phakhodee.

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Duangkamol, C., Pattarawarapan, M. & Phakhodee, W. Ultrasonic-assisted synthesis of carbodiimides from N,N′-disubstituted thioureas and ureas. Monatsh Chem 147, 1945–1949 (2016). https://doi.org/10.1007/s00706-016-1761-3

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  • DOI: https://doi.org/10.1007/s00706-016-1761-3

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